Fits gastric emptying time series from MRI or scintigraphic measurements using nonlinear mixed-model population fits with nlme and Bayesian methods with Stan; computes derived parameters such as t50 and AUC.

This package performs end-to-end analysis of gene clustersâ such as photosynthesis, carbon/nitrogen/sulfur cycling, carotenoid, antibiotic, or viral marker genes (e.g., capsid, polymerase, integrase)â from genomes and metagenomes. It parses Basic Local Alignment Search Tool (BLAST) results in tab-delimited format produced by tools like NCBI BLAST+ and Diamond BLASTp, filters Open Reading Frames (ORFs) by length, detects contiguous clusters of reference genes, optionally extracts genomic coordinates, merges functional annotations, and generates publication-ready arrow plots. The package works seamlessly with or without the coding sequences input and skips plotting when no functional groups are found. For more details see Li et al. (2023) <doi:10.1038/s41467-023-42193-7>.

Estimation and inference using the Generalized Maximum Entropy (GME) and Generalized Cross Entropy (GCE) framework, a flexible method for solving ill-posed inverse problems and parameter estimation under uncertainty (Golan, Judge, and Miller (1996, ISBN:978-0471145925) "Maximum Entropy Econometrics: Robust Estimation with Limited Data"). The package includes routines for generalized cross entropy estimation of linear models including the implementation of a GME-GCE two steps approach. Diagnostic tools, and options to incorporate prior information through support and prior distributions are available (Macedo, Cabral, Afreixo, Macedo and Angelelli (2025) <doi:10.1007/978-3-031-97589-9_21>). In particular, support spaces can be defined by the user or be internally computed based on the ridge trace or on the distribution of standardized regression coefficients. Different optimization methods for the objective function can be used. An adaptation of the normalized entropy aggregation (Macedo and Costa (2019) <doi:10.1007/978-3-030-26036-1_2> "Normalized entropy aggregation for inhomogeneous large-scale data") and a two-stage maximum entropy approach for time series regression (Macedo (2022) <doi:10.1080/03610918.2022.2057540>) are also available. Suitable for applications in econometrics, health, signal processing, and other fields requiring robust estimation under data constraints.

Fits a generalized linear density ratio model (GLDRM). A GLDRM is a semiparametric generalized linear model. In contrast to a GLM, which assumes a particular exponential family distribution, the GLDRM uses a semiparametric likelihood to estimate the reference distribution. The reference distribution may be any discrete, continuous, or mixed exponential family distribution. The model parameters, which include both the regression coefficients and the cdf of the unspecified reference distribution, are estimated by maximizing a semiparametric likelihood. Regression coefficients are estimated with no loss of efficiency, i.e. the asymptotic variance is the same as if the true exponential family distribution were known. Huang (2014) <doi:10.1080/01621459.2013.824892>. Huang and Rathouz (2012) <doi:10.1093/biomet/asr075>. Rathouz and Gao (2008) <doi:10.1093/biostatistics/kxn030>.

Introduces a Copilot'-like completion experience, but it knows how to talk to the objects in your R environment. ellmer chats are integrated directly into your RStudio and Positron sessions, automatically incorporating relevant context from surrounding lines of code and your global environment (like data frame columns and types). Open the package dialog box with a keyboard shortcut, type your request, and the assistant will stream its response directly into your documents.

This package provides ggplot2 equivalents of fixest::coefplot() and fixest::iplot(), for producing nice coefficient plots and interaction plots. Enables some additional functionality and convenience features, including grouped multi-'fixest object faceting and programmatic updates to existing plots (e.g., themes and aesthetics).

The geographic dimension plays a fundamental role in multidimensional systems. To define a geographic dimension in a star schema, we need a table with attributes corresponding to the levels of the dimension. Additionally, we will also need one or more geographic layers to represent the data using this dimension. The goal of this package is to support the definition of geographic dimensions from layers of geographic information related to each other. It makes it easy to define relationships between layers and obtain the necessary data from them.

This package provides stat_isotonic() to add weighted univariate isotonic regression curves.

The goal of this package is to translate between different languages without any Google API authentication which is pain and you must pay for the key, This package is free and lightweight.

This package contains the implementation of a binary large margin classifier based on Gabriel Graph. References for this method can be found in L.C.B. Torres et al. (2015) <doi:10.1049/el.2015.1644>.

Data sets included here are for use with package GEOmap. These include world map, USA map, Coso map, Japan Map.

This package provides a series of aliases to commonly used but difficult to remember ggplot2 sequences.

This package provides functions for obtaining the probability of detection, for grab samples selection by using two different methods such as systematic or random based on two-state Markov chain model. For detection probability calculation, we used results from Bhat, U. and Lal, R. (1988) <doi:10.2307/1427041>.

Estimates the parameters and nonparametric functions of an ARCH-m(X) model with exogenous covariates, estimates the parameters and nonparametric functions of an Additive ARCH-m(X) model with exogenous covariates, estimates the parameters of a GARCH-X model with exogenous covariates, performs hypothesis tests for the covariates returning the p-values, and performs stepwise variable selection on the exogenous covariates, and uses False Discovery Rate p-value corrections to select the exogenous variables.

Individual-based simulations forward in time, simulating how patterns in ancestry along the genome change after admixture. Full description can be found in Janzen (2021) <doi:10.1111/2041-210X.13612>.

This package provides Gaussian process (GP) regression tools for social science inference problems. GPs combine flexible nonparametric regression with principled uncertainty quantification: rather than committing to a single model fit, the posterior reflects lesser knowledge at the edge of or beyond the observed data, where other approaches become highly model-dependent. The package reduces user-chosen hyperparameters from three to zero and supplies convenience functions for regression discontinuity (gp_rdd()), interrupted time-series (gp_its()), and general GP fitting (gpss(), gp_train(), gp_predict()). Methods are described in Cho, Kim, and Hazlett (2026) <doi:10.1017/pan.2026.10032>.

Interfaces GAMS data (*.gdx) files with data.table's using the GAMS R package gdxrrw'. The gdxrrw package is available on the GAMS wiki: <https://support.gams.com/doku.php?id=gdxrrw:interfacing_gams_and_r>.

This package provides one-liner functions for common legend and guide operations in ggplot2'. Simplifies legend positioning, styling, wrapping, and collection across multi-panel plots created with patchwork or cowplot'.

Visualise overlapping time series lines as a heatmap of line density. Provides a ggplot2 statistic implementing the DenseLines algorithm, which "normalizes time series by the arc length to compute accurate densities" (Moritz and Fisher, 2018) <doi:10.48550/arXiv.1808.06019>.

Package for Genetic Epidemiologic Methods Developed at MSKCC. It contains functions to calculate haplotype specific odds ratio and the power of two stage design for GWAS studies.

This package provides a framework to detect Differential Item Functioning (DIF) in Generalized Partial Credit Models (GPCM) and special cases of the GPCM as proposed by Schauberger and Mair (2019) <doi:10.3758/s13428-019-01224-2>. A joint model is set up where DIF is explicitly parametrized and penalized likelihood estimation is used for parameter selection. The big advantage of the method called GPCMlasso is that several variables can be treated simultaneously and that both continuous and categorical variables can be used to detect DIF.

Estimate Gaussian graphical models with nonconvex penalties, including methods described by Williams (2020) <doi:10.31234/osf.io/ad57p>. Penalties include atan (Wang and Zhu, 2016) <doi:10.1155/2016/6495417>, seamless L0 (Dicker, Huang and Lin, 2013) <doi:10.5705/ss.2011.074>, exponential (Wang, Fan and Zhu, 2018) <doi:10.1007/s10463-016-0588-3>, smooth integration of counting and absolute deviation (Lv and Fan, 2009) <doi:10.1214/09-AOS683>, logarithm (Mazumder, Friedman and Hastie, 2011) <doi:10.1198/jasa.2011.tm09738>, Lq, smoothly clipped absolute deviation (Fan and Li, 2001) <doi:10.1198/016214501753382273>, and minimax concave penalty (Zhang, 2010) <doi:10.1214/09-AOS729>. The package also provides extensions for variable inclusion probabilities, multiple regression coefficients, and statistical inference (Janková and van de Geer, 2015) <doi:10.1214/15-EJS1031>.

This package provides a simple way to translate text elements in ggplot2 plots using a dictionary-based approach.

Model and estimate the model parameters for the spatial model of individual-level infectious disease transmission in Susceptible-Infected-Recovered (SIR) framework.