This package provides functions and a graphical user interface for graphical described multiple test procedures.

Generalized meta-analysis is a technique for estimating parameters associated with a multiple regression model through meta-analysis of studies which may have information only on partial sets of the regressors. It estimates the effects of each variable while fully adjusting for all other variables that are measured in at least one of the studies. Using algebraic relationships between regression parameters in different dimensions, a set of moment equations is specified for estimating the parameters of a maximal model through information available on sets of parameter estimates from a series of reduced models available from the different studies. The specification of the equations requires a reference dataset to estimate the joint distribution of the covariates. These equations are solved using the generalized method of moments approach, with the optimal weighting of the equations taking into account uncertainty associated with estimates of the parameters of the reduced models. The proposed framework is implemented using iterated reweighted least squares algorithm for fitting generalized linear regression models. For more details about the method, please see pre-print version of the manuscript on generalized meta-analysis by Prosenjit Kundu, Runlong Tang and Nilanjan Chatterjee (2018) <doi:10.1093/biomet/asz030>.The current version (0.2.0) is updated to address some of the stability issues in the previous version (0.1).

Data sets and scripts used in the book Generalized Additive Models: An Introduction with R', Wood (2006,2017) CRC.

Generalized promotion time cure model (GPTCM) via Bayesian hierarchical modeling for multiscale data integration (Zhao et al. (2025) <doi:10.48550/arXiv.2509.01001>). The Bayesian GPTCMs are applicable for both low- and high-dimensional data.

Implementation of various inference and simulation tools to apply generalized additive models to bivariate dependence structures and non-simplified vine copulas.

Implementation of several goodness-of-fit tests for functional data. Currently, mostly related with the functional linear model with functional/scalar response and functional/scalar predictor. The package allows for the replication of the data applications considered in Garcà a-Portugués, à lvarez-Liébana, à lvarez-Pérez and González-Manteiga (2021) <doi:10.1111/sjos.12486>.

Read data files readable by gnumeric into R'. Can read whole sheet or a range, from several file formats, including the native format of gnumeric'. Reading is done by using ssconvert (a file converter utility included in the gnumeric distribution <http://www.gnumeric.org>) to convert the requested part to CSV. From gnumeric files (but not other formats) can list sheet names and sheet sizes or read all sheets.

Computational representations of glycan compositions and structures, including details such as linkages, anomers, and substituents. Supports varying levels of monosaccharide specificity (e.g., "Hex" or "Gal") and ambiguous linkages. Provides robust parsing and generation of IUPAC-condensed structure strings. Optimized for vectorized operations on glycan structures, with efficient handling of duplications. As the cornerstone of the glycoverse ecosystem, this package delivers the foundational data structures that power glycomics and glycoproteomics analysis workflows.

This package provides tools and methods to apply the model Geospatial Regression Equation for European Nutrient losses (GREEN); Grizzetti et al. (2005) <doi:10.1016/j.jhydrol.2004.07.036>; Grizzetti et al. (2008); Grizzetti et al. (2012) <doi:10.1111/j.1365-2486.2011.02576.x>; Grizzetti et al. (2021) <doi:10.1016/j.gloenvcha.2021.102281>.

Gene-Ranking Analysis of Pathway Expression (GRAPE) is a tool for summarizing the consensus behavior of biological pathways in the form of a template, and for quantifying the extent to which individual samples deviate from the template. GRAPE templates are based only on the relative rankings of the genes within the pathway and can be used for classification of tissue types or disease subtypes. GRAPE can be used to represent gene-expression samples as vectors of pathway scores, where each pathway score indicates the departure from a given collection of reference samples. The resulting pathway- space representation can be used as the feature set for various applications, including survival analysis and drug-response prediction. Users of GRAPE should use the following citation: Klein MI, Stern DF, and Zhao H. GRAPE: A pathway template method to characterize tissue-specific functionality from gene expression profiles. BMC Bioinformatics, 18:317 (June 2017).

This package provides a set of high efficient functions to decode identifiers of National Football League players.

Allows get address and port of the free proxy server, from one of two services <http://gimmeproxy.com/> or <https://getproxylist.com/>. And it's easy to redirect your Internet connection through a proxy server.

This package contains all the data and functions used in Generalized Linear Models, 2nd edition, by Jeff Gill and Michelle Torres. Examples to create all models, tables, and plots are included for each data set.

The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

Implementation of spatial graph-theoretic genetic gravity models. The model framework is applicable for other types of spatial flow questions. Includes functions for constructing spatial graphs, sampling and summarizing associated raster variables and building unconstrained and singly constrained gravity models.

Estimation of the cutpoint defined by the Generalized Symmetry point in a binary classification setting based on a continuous diagnostic test or marker. Two methods have been implemented to construct confidence intervals for this optimal cutpoint, one based on the Generalized Pivotal Quantity and the other based on Empirical Likelihood. Numerical and graphical outputs for these two methods are easily obtained.

An R package that allows for combining tree-boosting with Gaussian process and mixed effects models. It also allows for independently doing tree-boosting as well as inference and prediction for Gaussian process and mixed effects models. See <https://github.com/fabsig/GPBoost> for more information on the software and Sigrist (2022, JMLR) <https://www.jmlr.org/papers/v23/20-322.html> and Sigrist (2023, TPAMI) <doi:10.1109/TPAMI.2022.3168152> for more information on the methodology.

This package provides a novel PRS model is introduced to enhance the prediction accuracy by utilising GxE effects. This package performs Genome Wide Association Studies (GWAS) and Genome Wide Environment Interaction Studies (GWEIS) using a discovery dataset. The package has the ability to obtain polygenic risk scores (PRSs) for a target sample. Finally it predicts the risk values of each individual in the target sample. Users have the choice of using existing models (Li et al., 2015) <doi:10.1093/annonc/mdu565>, (Pandis et al., 2013) <doi:10.1093/ejo/cjt054>, (Peyrot et al., 2018) <doi:10.1016/j.biopsych.2017.09.009> and (Song et al., 2022) <doi:10.1038/s41467-022-32407-9>, as well as newly proposed models for genomic risk prediction (refer to the URL for more details).

This package provides functions for matching student-answers to teacher answers for a variety of data types.

Generating, evaluating, and selecting initialization strategies for Gaussian Mixture Models (GMMs), along with functions to run the Expectation-Maximization (EM) algorithm. Initialization methods are compared using log-likelihood, and the best-fitting model can be selected using BIC. Methods build on initialization strategies for finite mixture models described in Michael and Melnykov (2016) <doi:10.1007/s11634-016-0264-8> and Biernacki et al. (2003) <doi:10.1016/S0167-9473(02)00163-9>, and on the EM algorithm of Dempster et al. (1977) <doi:10.1111/j.2517-6161.1977.tb01600.x>. Background on model-based clustering includes Fraley and Raftery (2002) <doi:10.1198/016214502760047131> and McLachlan and Peel (2000, ISBN:9780471006268).

Local structure in genomic data often induces dependence between observations taken at different genomic locations. Ignoring this dependence leads to underestimation of the standard error of parameter estimates. This package uses block bootstrapping to estimate asymptotically correct standard errors of parameters from any standard generalised linear model that may be fit by the glm() function.

To calculate the relative risk (RR) for the generalized additive model.

Spatial data plus the power of the ggplot2 framework means easier mapping when input data are already in the form of spatial objects.

Convert GDP time series data from one unit to another. All common GDP units are included, i.e. current and constant local currency units, US$ via market exchange rates and international dollars via purchasing power parities.