This package provides a big data version for fitting cumulative probability models using the orm() function from the rms package. See Liu et al. (2017) <DOI:10.1002/sim.7433> for details.

Data personally collected about the spread of COVID-19 (SARS-COV-2) in Tunisia <https://github.com/MounaBelaid/covid19datatunisia>.

Light weight implementation of the standard distribution functions for the chi distribution, wrapping those for the chi-squared distribution in the stats package.

Calculates daily climate water balance for irrigation purposes and also calculates the reference evapotranspiration (ET) using three methods, Penman and Monteith (Allen et al. 1998, ISBN:92-5-104219-5); Priestley and Taylor (1972) <doi:10/cr3qwn>; or Hargreaves and Samani (1985) <doi:10.13031/2013.26773>. Users may specify a management allowed depletion (MAD), which is used to suggest when to irrigate. The functionality allows for the use of crop and water stress coefficients as well.

Includes several classifications such as International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD10), Anatomical Therapeutic Chemical (ATC) Classification, The International Classification of Diseases for Oncology (ICD-O-3), and International Classification of Primary Care (ICPC). Includes function that adds descriptive label to code value. Depending on classification following languages are available: English, Finnish, Swedish, and Latin.

This package provides functions and command-line user interface to generate allocation sequence by covariate-adaptive randomization for clinical trials. The package currently supports six covariate-adaptive randomization procedures. Three hypothesis testing methods that are valid and robust under covariate-adaptive randomization are also available in the package to facilitate the inference for treatment effect under the included randomization procedures. Additionally, the package provides comprehensive and efficient tools to allow one to evaluate and compare the performance of randomization procedures and tests based on various criteria. See Ma W, Ye X, Tu F, and Hu F (2023) <doi: 10.18637/jss.v107.i02> for details.

This package provides tools for estimation and clustering of spherical data, seamlessly integrated with the flexmix package. Includes the necessary M-step implementations for both Poisson Kernel-Based Distribution (PKBD) and spherical Cauchy distribution. Additionally, the package provides random number generators for PKBD and spherical Cauchy distribution. Methods are based on Golzy M., Markatou M. (2020) <doi:10.1080/10618600.2020.1740713>, Kato S., McCullagh P. (2020) <doi:10.3150/20-bej1222> and Sablica L., Hornik K., Leydold J. (2023) <doi:10.1214/23-ejs2149>.

Manipulate and view coronavirus data and other societally relevant data at a basic level.

Create data summaries for quality control, extensive reports for exploring data, as well as publication-ready univariate or bivariate tables in several formats (plain text, HTML,LaTeX, PDF, Word or Excel. Create figures to quickly visualise the distribution of your data (boxplots, barplots, normality-plots, etc.). Display statistics (mean, median, frequencies, incidences, etc.). Perform the appropriate tests (t-test, Analysis of variance, Kruskal-Wallis, Fisher, log-rank, ...) depending on the nature of the described variable (normal, non-normal or qualitative). Summarize genetic data (Single Nucleotide Polymorphisms) data displaying Allele Frequencies and performing Hardy-Weinberg Equilibrium tests among other typical statistics and tests for these kind of data.

Load and analyze updated time series worldwide data of reported cases for the Novel Coronavirus Disease (COVID-19) from different sources, including the Johns Hopkins University Center for Systems Science and Engineering (JHU CSSE) data repository <https://github.com/CSSEGISandData/COVID-19>, "Our World in Data" <https://github.com/owid/> among several others. The datasets reporting the COVID-19 cases are available in two main modalities, as a time series sequences and aggregated data for the last day with greater spatial resolution. Several analysis, visualization and modelling functions are available in the package that will allow the user to compute and visualize total number of cases, total number of changes and growth rate globally or for an specific geographical location, while at the same time generating models using these trends; generate interactive visualizations and generate Susceptible-Infected-Recovered (SIR) model for the disease spread.

The c060 package provides additional functions to perform stability selection, model validation and parameter tuning for glmnet models.

Create an addin in Rstudio to do fill-in-the-middle (FIM) and chat with latest Mistral AI models for coding, Codestral and Codestral Mamba'. For more details about Mistral AI API': <https://docs.mistral.ai/getting-started/quickstart/> and <https://docs.mistral.ai/api/>. For more details about Codestral model: <https://mistral.ai/news/codestral>; about Codestral Mamba': <https://mistral.ai/news/codestral-mamba>.

Exploits dynamical seasonal forecasts in order to provide information relevant to stakeholders at the seasonal timescale. The package contains process-based methods for forecast calibration, bias correction, statistical and stochastic downscaling, optimal forecast combination and multivariate verification, as well as basic and advanced tools to obtain tailored products. This package was developed in the context of the ERA4CS project MEDSCOPE and the H2020 S2S4E project and includes contributions from ArticXchange project founded by EU-PolarNet 2. Implements methods described in Pérez-Zanón et al. (2022) <doi:10.5194/gmd-15-6115-2022>, Doblas-Reyes et al. (2005) <doi:10.1111/j.1600-0870.2005.00104.x>, Mishra et al. (2018) <doi:10.1007/s00382-018-4404-z>, Sanchez-Garcia et al. (2019) <doi:10.5194/asr-16-165-2019>, Straus et al. (2007) <doi:10.1175/JCLI4070.1>, Terzago et al. (2018) <doi:10.5194/nhess-18-2825-2018>, Torralba et al. (2017) <doi:10.1175/JAMC-D-16-0204.1>, D'Onofrio et al. (2014) <doi:10.1175/JHM-D-13-096.1>, Verfaillie et al. (2017) <doi:10.5194/gmd-10-4257-2017>, Van Schaeybroeck et al. (2019) <doi:10.1016/B978-0-12-812372-0.00010-8>, Yiou et al. (2013) <doi:10.1007/s00382-012-1626-3>.

This model fitting tool incorporates cyclic coordinate descent and majorization-minimization approaches to fit a variety of regression models found in large-scale observational healthcare data. Implementations focus on computational optimization and fine-scale parallelization to yield efficient inference in massive datasets. Please see: Suchard, Simpson, Zorych, Ryan and Madigan (2013) <doi:10.1145/2414416.2414791>.

Deconvolution of bulk RNA-Sequencing data into proportions of cells based on a reference single-cell RNA-Sequencing dataset using high-dimensional geometric methodology.

Puzzle game that can be played in the R console. Help the alien to find the ship.

This package provides a suite of computer model test functions that can be used to test and evaluate algorithms for Bayesian (also known as sequential) optimization. Some of the functions have known functional forms, however, most are intended to serve as black-box functions where evaluation requires running computer code that reveals little about the functional forms of the objective and/or constraints. The primary goal of the package is to provide users (especially those who do not have access to real computer models) a source of reproducible and shareable examples that can be used for benchmarking algorithms. The package is a living repository, and so more functions will be added over time. For function suggestions, please do contact the author of the package.

This package provides a simple way to assess the stability of candidate housekeeping genes is implemented in this package.

Eases the use of ecotoxicological effect models. Can simulate common toxicokinetic-toxicodynamic (TK/TD) models such as General Unified Threshold models of Survival (GUTS) and Lemna. It can derive effects and effect profiles (EPx) from scenarios. It supports the use of tidyr workflows employing the pipe symbol. Time-consuming tasks can be parallelized.

This package provides a set of functions for applying a restricted linear algebra to the analysis of count-based data. See the accompanying preprint manuscript: "Normalizing need not be the norm: count-based math for analyzing single-cell data" Church et al (2022) <doi:10.1101/2022.06.01.494334> This tool is specifically designed to analyze count matrices from single cell RNA sequencing assays. The tools implement several count-based approaches for standard steps in single-cell RNA-seq analysis, including scoring genes and cells, comparing cells and clustering, calculating differential gene expression, and several methods for rank reduction. There are many opportunities for further optimization that may prove useful in the analysis of other data. We provide the source code freely available at <https://github.com/shchurch/countland> and encourage users and developers to fork the code for their own purposes.

This package provides a toolkit for computing and visualizing CAPL-2 (Canadian Assessment of Physical Literacy, Second Edition; <https://www.capl-eclp.ca>) scores and interpretations from raw data.

Download imagery tiles to a standard cache and load the data into raster objects. Facilities for AWS terrain <https://registry.opendata.aws/terrain-tiles/> terrain and Mapbox <https://www.mapbox.com/> servers are provided.

Account for uncertainty when working with ranks. Estimate standard errors consistently in linear regression with ranked variables. Construct confidence sets of various kinds for positions of populations in a ranking based on values of a certain feature and their estimation errors. Theory based on Mogstad, Romano, Shaikh, and Wilhelm (2023)<doi:10.1093/restud/rdad006> and Chetverikov and Wilhelm (2023) <doi:10.48550/arXiv.2310.15512>.

Implementation of the Cluster Estimated Standard Errors (CESE) proposed in Jackson (2020) <DOI:10.1017/pan.2019.38> to compute clustered standard errors of linear coefficients in regression models with grouped data.