T (extent of the primary tumor), N (absence or presence and extent of regional lymph node metastasis) and M (absence or presence of distant metastasis) are three components to describe the anatomical tumor extent. TNM stage is important in treatment decision-making and outcome predicting. The existing oropharyngeal Cancer (OPC) TNM stages have not made distinction of the two sub sites of Human papillomavirus positive (HPV+) and Human papillomavirus negative (HPV-) diseases. We developed novel criteria to assess performance of the TNM stage grouping schemes based on parametric modeling adjusting on important clinical factors. These criteria evaluate the TNM stage grouping scheme in five different measures: hazard consistency, hazard discrimination, explained variation, likelihood difference, and balance. The methods are described in Xu, W., et al. (2015) <https://www.austinpublishinggroup.com/biometrics/fulltext/biometrics-v2-id1014.php>.

This package provides functions to perform propensity score matching on rolling entry interventions for which a suitable "entry" date is not observed for nonparticipants. For more details, please reference Witman et al. (2018) <doi:10.1111/1475-6773.13086>.

Use R to interface with the TD Ameritrade API <https://developer.tdameritrade.com/>. Functions include authentication, trading, price requests, account information, and option chains. A user will need a TD brokerage account and TD Ameritrade developer app. See README for authentication process and examples.

Understanding heterogeneous causal effects based on pretreatment covariates is a crucial step in modern empirical work in data science. Building on the recent developments in Calonico et al (2025) <https://rdpackages.github.io/references/Calonico-Cattaneo-Farrell-Palomba-Titiunik_2025_HTERD.pdf>, this package provides tools for estimation and inference of heterogeneous treatment effects in Regression Discontinuity (RD) Designs. The package includes two main commands: rdhte to conduct estimation and robust bias-corrected inference for conditional RD treatment effects (given choice of bandwidth parameter); rdbwhte', which implements automatic bandwidth selection methods; and rdhte_lincom to test linear combinations of parameters.

Simple, native RethinkDB client.

Exploration of pharmacometrics data involves both general tools (transformation and plotting) and specific techniques (non-compartmental analysis). This kind of exploration is generally accomplished by utilizing different packages. The purpose of ruminate is to create a shiny interface to make these tools more broadly available while creating reproducible results.

In order to facilitate parsing of http requests and creating appropriate responses this package provides two classes to handle a lot of the housekeeping involved in working with http exchanges. The infrastructure builds upon the rook specification and is thus well suited to be combined with httpuv based web servers.

This package provides tools for implementing Retrieval-Augmented Generation (RAG) workflows with Large Language Models (LLM). Includes functions for document processing, text chunking, embedding generation, storage management, and content retrieval. Supports various document types and embedding providers ('Ollama', OpenAI'), with DuckDB as the default storage backend. Integrates with the ellmer package to equip chat objects with retrieval capabilities. Designed to offer both sensible defaults and customization options with transparent access to intermediate outputs. For a review of retrieval-augmented generation methods, see Gao et al. (2023) "Retrieval-Augmented Generation for Large Language Models: A Survey" <doi:10.48550/arXiv.2312.10997>.

An interface to iDigBio's search API that allows downloading specimen records. Searches are returned as a data.frame. Other functions such as the metadata end points return lists of information. iDigBio is a US project focused on digitizing and serving museum specimen collections on the web. See <https://www.idigbio.org> for information on iDigBio.

Gather boxscore, play-by-play, and auxiliary data from Major League Volleyball (MLV) <https://provolleyball.com>, League One Volleyball Pro (LOVB Pro) <https://www.lovb.com/pro-league>, and Athletes Unlimited Pro Volleyball <https://auprosports.com/volleyball/> to create a repository of basic and advanced statistics for teams and players.

R interface to the LTP'-Cloud service for Natural Language Processing in Chinese (http://www.ltp-cloud.com/).

Linear regression functions using Huber and bisquare psi functions. Optimal weights are calculated using IRLS algorithm.

Assists in statistical model building to find optimal and semi-optimal higher order interactions and best subsets. Uses the lm(), glm(), and other R functions to fit models generated from a feasible solution algorithm. Discussed in Subset Selection in Regression, A Miller (2002). Applied and explained for least median of squares in Hawkins (1993) <doi:10.1016/0167-9473(93)90246-P>. The feasible solution algorithm comes up with model forms of a specific type that can have fixed variables, higher order interactions and their lower order terms.

This package provides an Rcmdr "plug-in" based on the TeachingDemos package, and is primarily for illustrative purposes.

Leverages the functionality of clipboard.js', a JavaScript library for HMTL5-based copy to clipboard from web pages (see <https://clipboardjs.com> for more information), and provides a reactive copy-to-clipboard UI button component, called rclipButton', and a a reactive copy-to-clipboard UI link component, called rclipLink', for shiny R applications.

Wraps tiny_obj_loader C++ library for reading the Wavefront OBJ 3D file format including both mesh objects and materials files. The resultant R objects are either structured to match the tiny_obj_loader internal data representation or in a form directly compatible with the rgl package.

An HTTP API client for Lemmy (<https://github.com/LemmyNet/lemmy>) in R. Code and documentation are generated from the official JavaScript client source (<https://github.com/LemmyNet/lemmy-js-client>).

Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The VODE and LSODA are in the public domain. The information is available in the inst/COPYRIGHTS.

Data objects in R can be rendered as HTML tables using the JavaScript library ag-grid (typically via R Markdown or Shiny'). The ag-grid library has been included in this R package. The package name RagGrid is an abbreviation of R agGrid'.

Easy-to-use functions for downloading air quality data from the Mexican National Air Quality Information System (SINAICA). Allows you to query pollution and meteorological parameters from more than a hundred monitoring stations located throughout Mexico. See <https://sinaica.inecc.gob.mx> for more information.

Simplified scenario testing and sensitivity analysis, redesigned to use packages future and furrr'. Provides functions for generating function argument sets using one-factor-at-a-time (OFAT) and (sampled) permutations.

Convert one biological ID to another of rice (Oryza sativa). Rice(Oryza sativa) has more than one form gene ID for the genome. The two main gene ID for rice genome are the RAP (The Rice Annotation Project, <https://rapdb.dna.affrc.go.jp/>, and the MSU(The Rice Genome Annotation Project, <http://rice.plantbiology.msu.edu/>. All RAP rice gene IDs are of the form Os##g####### as explained on the website <https://rapdb.dna.affrc.go.jp/>. All MSU rice gene IDs are of the form LOC_Os##g##### as explained on the website <http://rice.plantbiology.msu.edu/analyses_nomenclature.shtml>. All SYMBOL rice gene IDs are the unique name on the NCBI(National Center for Biotechnology Information, <https://www.ncbi.nlm.nih.gov/>. The TRANSCRIPTID, is the transcript id of rice, are of the form Os##t#######. The researchers usually need to converter between various IDs. Such as converter RAP to SYMBOLS for function searching on NCBI. There are a lot of websites with the function for converting RAP to MSU or MSU to RA, such as ID Converter <https://rapdb.dna.affrc.go.jp/tools/converter>. But it is difficult to convert super multiple IDs on these websites. The package can convert all IDs between the three IDs (RAP, MSU and SYMBOL) regardless of the number.

This package provides functions to simulate and analyze data for a regression model with an interval censored covariate, as described in Morrison et al. (2021) <doi:10.1111/biom.13472>.

This package provides a data mining approach for longitudinal and clustered data, which combines the structure of mixed effects model with tree-based estimation methods. See Sela, R.J. and Simonoff, J.S. (2012) RE-EM trees: a data mining approach for longitudinal and clustered data <doi:10.1007/s10994-011-5258-3>.