This package provides datasets and functions for the class "Modelling and Data Analysis for Pharmaceutical Sciences". The datasets can be used to present various methods of data analysis and statistical modeling. Functions for data visualization are also implemented.

Methodology for subgroup selection in the context of isotonic regression including methods for sub-Gaussian errors, classification, homoscedastic Gaussian errors and quantile regression. See the documentation of ISS(). Details can be found in the paper by Müller, Reeve, Cannings and Samworth (2023) <arXiv:2305.04852v2>.

This function predicts item response probabilities and item responses using the item-focused tree model. The item-focused tree model combines logistic regression with recursive partitioning to detect Differential Item Functioning in dichotomous items. The model applies partitioning rules to the data, splitting it into homogeneous subgroups, and uses logistic regression within each subgroup to explain the data. Differential Item Functioning detection is achieved by examining potential group differences in item response patterns. This method is useful for understanding how different predictors, such as demographic or psychological factors, influence item responses across subgroups.

High resolution mass spectrometry yields often large data sets of spectra from compounds which are not present in available libraries. These spectra need to be annotated and interpreted. InterpretMSSpectrum provides a set of functions to perform such tasks for Electrospray-Ionization and Atmospheric-Pressure-Chemical-Ionization derived data in positive and negative ionization mode.

This package provides functionality to perform a likelihood-free method for estimating the parameters of complex models that results in a simulated sample from the posterior distribution of model parameters given targets. The method begins with a accept/reject approximate bayes computation (ABC) step applied to a sample of points from the prior distribution of model parameters. Accepted points result in model predictions that are within the initially specified tolerance intervals around the target points. The sample is iteratively updated by drawing additional points from a mixture of multivariate normal distributions, accepting points within tolerance intervals. As the algorithm proceeds, the acceptance intervals are narrowed. The algorithm returns a set of points and sampling weights that account for the adaptive sampling scheme. For more details see Rutter, Ozik, DeYoreo, and Collier (2018) <arXiv:1804.02090>.

This package provides a collection of functions for working with time series data, including functions for drawing, decomposing, and forecasting. Includes capabilities to compare multiple series and fit both additive and multiplicative models. Used by iNZight', a graphical user interface providing easy exploration and visualisation of data for students of statistics, available in both desktop and online versions. Holt (1957) <doi:10.1016/j.ijforecast.2003.09.015>, Winters (1960) <doi:10.1287/mnsc.6.3.324>, Cleveland, Cleveland, & Terpenning (1990) "STL: A Seasonal-Trend Decomposition Procedure Based on Loess".

Read data from LimeSurvey (<https://www.limesurvey.org/>) in a comfortable way. Heavily inspired by limer (<https://github.com/cloudyr/limer/>), which lacked a few comfort features for me.

Compute missing values on a training data set and impute them on a new data set. Current available options are median/mode and random forest.

This package implements the conditional inference forest approach to modeling interval-censored survival data. It also provides functions to tune the parameters and evaluate the model fit. See Yao et al. (2019) <arXiv:1901.04599>.

Know which loop iteration the code execution is up to by including a single, convenient function call inside the loop.

API wrapper that contains functions to retrieve data from the IsoMemo partnership databases. Web services for API: <https://isomemodb.com/api/v1/iso-data>.

This package provides tools to extract information from the Intergovernmental Organizations ('IGO') Database (v3), provided by the Correlates of War Project <https://correlatesofwar.org/>. See also Pevehouse, J. C. et al. (2020) <doi:10.1177/0022343319881175>.

Get open statistical data and metadata disseminated by the National Statistics Institute of Spain (INE). The functions return data frames with the requested information thanks to calls to the INE API <https://www.ine.es/dyngs/DAB/index.htm?cid=1100>.

Fit a full or subsampling bagging survival tree on a mixture of population (susceptible and nonsusceptible) using either a pseudo R2 criterion or an adjusted Logrank criterion. The predictor is evaluated using the Out Of Bag Integrated Brier Score (IBS) and several scores of importance are computed for variable selection. The thresholds values for variable selection are computed using a nonparametric permutation test. See Cyprien Mbogning and Philippe Broet (2016)<doi:10.1186/s12859-016-1090-x> for an overview about the methods implemented in this package.

Deconvolution of mixed tumour profiles into normal and cancer for each patient, using the ISOpure algorithm in Quon et al. Genome Medicine, 2013 5:29. Deconvolution requires mixed tumour profiles and a set of unmatched "basis" normal profiles.

When you want to install R package or download file from GitHub, but you can't access GitHub, this package helps you install R packages or download file from GitHub via the proxy website <https://gh-proxy.com/> or <https://ghfast.top/>, which is in real-time sync with GitHub.

This package provides utility functions to deal with Italian fiscal code ('codice fiscale').

An implementation of the correction methods proposed by Shu and Yi (2017) <doi:10.1177/0962280217743777> for the inverse probability weighted (IPW) estimation of average treatment effect (ATE) with misclassified binary outcomes. Logistic regression model is assumed for treatment model for all implemented correction methods, and is assumed for the outcome model for the implemented doubly robust correction method. Misclassification probability given a true value of the outcome is assumed to be the same for all individuals.

In view of the analysis of the structural characteristics of the tripartite network has been complete, however, there is still a lack of a unified operation that can quickly obtain the corresponding characteristics of the tripartite network. To solve this insufficiency, ILSM was designed for supporting calculating such metrics of tripartite networks by functions of this R package.

This package implements a variety of nonparametric and parametric methods that are commonly used when the data set is a mixture of paired observations and independent samples. The package also calculates and returns values of different tests with their corresponding p-values. Bhoj, D. S. (1991) <doi:10.1002/bimj.4710330108> "Testing equality of means in the presence of correlation and missing data". Dubnicka, S. R., Blair, R. C., and Hettmansperger, T. P. (2002) <doi:10.22237/jmasm/1020254460> "Rank-based procedures for mixed paired and two-sample designs". Einsporn, R. L. and Habtzghi, D. (2013) <https://pdfs.semanticscholar.org/89a3/90bafeb2bc41ed4414533cfd5ab84a6b54b6.pdf> "Combining paired and two-sample data using a permutation test". Ekbohm, G. (1976) <doi:10.1093/biomet/63.2.299> "On comparing means in the paired case with incomplete data on both responses". Lin, P. E. and Stivers, L. E. (1974) <doi:10.1093/biomet/61.2.325> On difference of means with incomplete data". Maritz, J. S. (1995) <doi:10.1111/j.1467-842x.1995.tb00649.x> "A permutation paired test allowing for missing values".

Import and export data from the most common statistical formats by using R functions that guarantee the least loss of the data information, giving special attention to the date variables and the labelled ones.

This package provides function to read data from the Igor Pro data analysis program by Wavemetrics'. The data formats supported are Igor packed experiment format ('pxp') and Igor binary wave ('ibw'). See: <https://www.wavemetrics.com/> for details. Also includes functions to load special pxp files produced by the Igor Pro Neuromatic and Nclamp packages for recording and analysing neuronal data. See <https://github.com/SilverLabUCL/NeuroMatic> for details.

Carries out instrumental variable estimation of causal effects, including power analysis, sensitivity analysis, and diagnostics. See Kang, Jiang, Zhao, and Small (2020) <http://pages.cs.wisc.edu/~hyunseung/> for details.

This package implements an algorithm for fitting a generative model with an intractable likelihood using only box constraints on the parameters. The implemented algorithm consists of two phases. The first phase (global search) aims to identify the region containing the best solution, while the second phase (local search) refines this solution using a trust-region version of the Fisher scoring method to solve a quasi-likelihood equation. See Guido Masarotto (2025) <doi:10.48550/arXiv.2511.08180> for the details of the algorithm and supporting results.