The implement of integrative analysis methods based on a two-part penalization, which realizes dimension reduction analysis and mining the heterogeneity and association of multiple studies with compatible designs. The software package provides the integrative analysis methods including integrative sparse principal component analysis (Fang et al., 2018), integrative sparse partial least squares (Liang et al., 2021) and integrative sparse canonical correlation analysis, as well as corresponding individual analysis and meta-analysis versions. References: (1) Fang, K., Fan, X., Zhang, Q., and Ma, S. (2018). Integrative sparse principal component analysis. Journal of Multivariate Analysis, <doi:10.1016/j.jmva.2018.02.002>. (2) Liang, W., Ma, S., Zhang, Q., and Zhu, T. (2021). Integrative sparse partial least squares. Statistics in Medicine, <doi:10.1002/sim.8900>.

This package provides facilities of general to specific model selection for exogenous regressors in 2SLS models. Furthermore, indicator saturation methods can be used to detect outliers and structural breaks in the sample.

Reproducible, programmatic retrieval of datasets from the Inter-university Consortium for Political and Social Research archive.

Interactive dendrogram that enables the user to select and color clusters, to zoom and pan the dendrogram, and to visualize the clustered data not only in a built-in heat map, but also in GGobi interactive plots and user-supplied plots. This is a backport of Qt-based idendro (<https://github.com/tsieger/idendro>) to base R graphics and Tcl/Tk GUI.

Develops stochastic models based on the Theory of Island Biogeography (TIB) of MacArthur and Wilson (1967) <doi:10.1023/A:1016393430551> and extensions. It implements methods to estimate colonization and extinction rates (including environmental variables) given presence-absence data, simulates community assembly, and performs model selection.

This package implements tests for the identifying assumptions of instrumental variable models, the local exclusion restriction and monotonicity conditions required for local average treatment effect identification. Covers Kitagawa (2015) <doi:10.3982/ECTA11974>, Mourifie and Wan (2017) <doi:10.1162/REST_a_00622>, and Frandsen, Lefgren, and Leslie (2023) <doi:10.1257/aer.20201860>. Includes a one-shot wrapper that runs all applicable tests on a fitted instrumental variable model. Dispatches on fixest and ivreg model objects.

This package provides a comprehensive toolkit for clinical Human Leukocyte Antigen (HLA) informatics, built on tidyverse <https://tidyverse.tidyverse.org/> principles and making use of genotype list string (GL string, Mack et al. (2023) <doi:10.1111/tan.15126>) for storing and computing HLA genotype data. Specific functionalities include: coercion of HLA data in tabular format to and from GL string; calculation of matching and mismatching in all directions, with multiple output formats; automatic formatting of HLA data for searching within a GL string; truncation of molecular HLA data to a specific number of fields; and reading HLA genotypes in HML files and extracting the GL string. This library is intended for research use. Any application making use of this package in a clinical setting will need to be independently validated according to local regulations.

This package provides tools for probabilistic taxon assignment with informatic sequence classification trees. See Wilkinson et al (2018) <doi:10.7287/peerj.preprints.26812v1>.

This package provides functions to query the IPGeolocation.io IP Location API (<https://ipgeolocation.io/documentation/ip-location-api.html>). Supports retrieval of IP location, ASN, network, currency, timezone, abuse, and security data. Response filtering is supported using fields and excludes parameters (dot notation supported), and optional objects can be requested via the include parameter. Returns parsed API responses as R objects.

Estimates item parameters of the two-parameter logistic (2PL) model in Item Response Theory (IRT) using the marginal Bayesian modal estimation via the Expectation-Maximization (EM) algorithm. The package calibrates item discrimination and difficulty parameters, yielding results comparable to software like BILOG-MG'.

This package implements the Information Matrix test for regression models following Cameron, A. C., & Trivedi, P. K. (1990) <https://cameron.econ.ucdavis.edu/research/imtest_impliedalternatives_ucdwp372.pdf> Decomposes the test into components for heteroscedasticity, skewness, and kurtosis to diagnose specific forms of misspecification. Provides both overall and component-wise statistics for model assessment.

The initial basic feasible solution (IBFS) is a significant step to achieve the minimal total cost (optimal solution) of the transportation problem. However, the existing methods of IBFS do not always provide a good feasible solution which can reduce the number of iterations to find the optimal solution. This initial basic feasible solution can be obtained by using any of the following methods. a) North West Corner Method. b) Least Cost Method. c) Row Minimum Method. d) Column Minimum Method. e) Vogel's Approximation Method. etc. For more technical details about the algorithms please refer below URLs. <https://theintactone.com/2018/05/24/ds-u2-topic-8-transportation-problems-initial-basic-feasible-solution/>. <https://www.brainkart.com/article/Methods-of-finding-initial-Basic-Feasible-Solutions_39037/>. <https://myhomeworkhelp.com/row-minima-method/>. <https://myhomeworkhelp.com/column-minima-method/>.

Uses data and researcher's beliefs on measurement error and instrumental variable (IV) endogeneity to generate the space of consistent beliefs across measurement error, instrument endogeneity, and instrumental relevance for IV regressions. Package based on DiTraglia and Garcia-Jimeno (2020) <doi:10.1080/07350015.2020.1753528>.

Facilitates the calculation of 40 different insulin sensitivity indices based on fasting, oral glucose tolerance test (OGTT), lipid (adipose), tracer (palmitate and glycerol rate), and DXA (fat mass) measurement values. Enables easy and accurate assessment of insulin sensitivity, critical for understanding and managing metabolic disorders like diabetes and obesity. Indices calculated are described in Gastaldelli (2022) <doi:10.1002/oby.23503>, Suleman (2024) <doi:10.1210/clinem/dgae275>, and Lorenzo (2010) <doi:10.1210/jc.2010-1144>.

The general workflow of most imputation methods is quite similar. The aim of this package is to provide parts of this general workflow to make the implementation of imputation methods easier. The heart of an imputation method is normally the used model. These models can be defined using the parsnip package or customized specifications. The rest of an imputation method are more technical specification e.g. which columns and rows should be used for imputation and in which order. These technical specifications can be set inside the imputation functions.

General purpose TIFF file I/O for R users. Currently the only such package with read and write support for TIFF files with floating point (real-numbered) pixels, and the only package that can correctly import TIFF files that were saved from ImageJ and write TIFF files than can be correctly read by ImageJ <https://imagej.net/ij/>. Also supports text image I/O.

This package contains a number of infix binary operators that may be useful in day to day practices.

The methods in this package adds to the functionality of the intamap package, such as bias correction and network optimization. Pebesma et al (2010) gives an overview of the methods behind and possible usage <doi:10.1016/j.cageo.2010.03.019>.

The Inductive Subgroup Comparison Approach ('ISCA') offers a way to compare groups that are internally differentiated and heterogeneous. It starts by identifying the social structure of a reference group against which a minority or another group is to be compared, yielding empirical subgroups to which minority members are then matched based on how similar they are. The modelling of specific outcomes then occurs within specific subgroups in which majority and minority members are matched. ISCA is characterized by its data-driven, probabilistic, and iterative approach and combines fuzzy clustering, Monte Carlo simulation, and regression analysis. ISCA_random_assignments() assigns subjects probabilistically to subgroups. ISCA_clustertable() provides summary statistics of each cluster across iterations. ISCA_modeling() provides Ordinary Least Squares regression results for each cluster across iterations. For further details please see Drouhot (2021) <doi:10.1086/712804>.

Time parceling method and Bayesian variability modeling methods for modeling within individual variability indicators as predictors.For more details, see <https://github.com/xliu12/IIVpredicitor>.

Distributional regression under stochastic order restrictions for numeric and binary response variables and partially ordered covariates. See Henzi, Ziegel, Gneiting (2020) <arXiv:1909.03725>.

Calculation of informative simultaneous confidence intervals for graphical described multiple test procedures and given information weights. Bretz et al. (2009) <doi:10.1002/sim.3495> and Brannath et al. (2024) <doi:10.48550/arXiv.2402.13719>. Furthermore, exploration of the behavior of the informative bounds in dependence of the information weights. Comparisons with compatible bounds are possible. Strassburger and Bretz (2008) <doi:10.1002/sim.3338>.

Based on large margin principle, this package performs feature selection methods: "IM4E"(Iterative Margin-Maximization under Max-Min Entropy Algorithm); "Immigrate"(Iterative Max-Min Entropy Margin-Maximization with Interaction Terms Algorithm); "BIM"(Boosted version of IMMIGRATE algorithm); "Simba"(Iterative Search Margin Based Algorithm); "LFE"(Local Feature Extraction Algorithm). This package also performs prediction for the above feature selection methods.

Compute onestep and multistep time series forecasts for machine learning models.