This package provides tools to visualize the results of a classification or a regression. The graphical displays include stacked plots, silhouette plots, quasi residual plots, class maps, predictions plots, and predictions correlation plots. Implements the techniques described and illustrated in Raymaekers J., Rousseeuw P.J., Hubert M. (2022). Class maps for visualizing classification results. \emphTechnometrics, 64(2), 151â 165. <doi:10.1080/00401706.2021.1927849> (open access), Raymaekers J., Rousseeuw P.J.(2022). Silhouettes and quasi residual plots for neural nets and tree-based classifiers. \emphJournal of Computational and Graphical Statistics, 31(4), 1332â 1343. <doi:10.1080/10618600.2022.2050249>, and Rousseeuw, P.J. (2026). Explainable Linear and Generalized Linear Models by the Predictions Plot. The American Statistician, 80, 157-163, <doi:10.1080/00031305.2025.2539235> (open access), and Montalcini, C., Rousseeuw, P.J. (2025). The bixplot: A variation on the boxplot suited for bimodal data, <doi:10.48550/arXiv.2510.09276> (open access). Examples can be found in the vignettes: "Discriminant_analysis_examples","K_nearest_neighbors_examples", "Support_vector_machine_examples", "Rpart_examples", "Random_forest_examples", "Neural_net_examples", "predsplot_examples", and "bixplot_examples".

Calculation of consensus values for atomic weights, isotope amount ratios, and isotopic abundances with the associated uncertainties using multivariate meta-regression approach for consensus building.

Fits a constrained regression model for an ordinal response with ordinal predictors and possibly others, Espinosa and Hennig (2019) <DOI:10.1007/s11222-018-9842-2>. The parameter estimates associated with an ordinal predictor are constrained to be monotonic. If a monotonicity direction (isotonic or antitonic) is not specified for an ordinal predictor by the user, then one of the available methods will either establish it or drop the monotonicity assumption. Two monotonicity tests are also available to test the null hypothesis of monotonicity over a set of parameters associated with an ordinal predictor.

Computes confidence intervals for the positive predictive value (PPV) and negative predictive value (NPV) based on varied scenarios. In situations where the proportion of diseased subjects does not correspond to the disease prevalence (e.g. case-control studies), this package provides two types of solutions: 1) five methods for estimating confidence intervals for PPV and NPV via ratio of two binomial proportions including Gart & Nam (1988), Walter (1975), MOVER-J (Laud, 2017), Fieller (1954), and Bootstrap (Efron, 1979); 2) three direct methods that compute the confidence intervals including Pepe (2003), Zhou (2007), and Delta. In prospective studies where the proportion of diseased subjects is an unbiased estimate of the disease prevalence, this package provides several methods for calculating the confidence intervals for PPV and NPV including Clopper-Pearson, Wald, Wilson, Agresti-Coull, and Beta. See the Details and References sections in the corresponding functions.

An R implementation of the Critical Path Method (CPM). CPM is a method used to estimate the minimum project duration and determine the amount of scheduling flexibility on the logical network paths within the schedule model. The flexibility is in terms of early start, early finish, late start, late finish, total float and free float. Beside, it permits to quantify the complexity of network diagram through the analysis of topological indicators. Finally, it permits to change the activities duration to perform what-if scenario analysis. The package was built based on following references: To make topological sorting and other graph operation, we use Csardi, G. & Nepusz, T. (2005) <https://www.researchgate.net/publication/221995787_The_Igraph_Software_Package_for_Complex_Network_Research>; For schedule concept, the reference was Project Management Institute (2017) <https://www.pmi.org/pmbok-guide-standards/foundational/pmbok>; For standards terms, we use Project Management Institute (2017) <https://www.pmi.org/pmbok-guide-standards/lexicon>; For algorithms on Critical Path Method development, we use Vanhoucke, M. (2013) <doi:10.1007/978-3-642-40438-2> and Vanhoucke, M. (2014) <doi:10.1007/978-3-319-04331-9>; And, finally, for topological definitions, we use Vanhoucke, M. (2009) <doi:10.1007/978-1-4419-1014-1>.

The Clinical Trials Network (CTN) of the U.S. National Institute of Drug Abuse sponsored the CTN-0094 research team to harmonize data sets from three nationally-representative clinical trials for opioid use disorder (OUD). The CTN-0094 team herein provides a coded collection of trial outcomes and endpoints used in various OUD clinical trials over the past 50 years. These coded outcome functions are used to contrast and cluster different clinical outcome functions based on daily or weekly patient urine screenings. Note that we abbreviate urine drug screen as "UDS" and urine opioid screen as "UOS". For the example data sets (based on clinical trials data harmonized by the CTN-0094 research team), UDS and UOS are largely interchangeable.

This package provides tools for the analysis, visualization, and manipulation of dynamical, social (Saqr et al. (2024) <doi:10.1007/978-3-031-54464-4_10>) and complex networks (Saqr et al. (2025) <doi:10.1145/3706468.3706513>). The package supports multiple network formats and offers flexible tools for heterogeneous, multi-layer, and hierarchical network analysis with simple syntax and extensive toolset.

This package provides functions to assess complex heterogeneity in the strength of a surrogate marker with respect to multiple baseline covariates, in either a randomized treatment setting or observational setting. For a randomized treatment setting, the functions assess and test for heterogeneity using both a parametric model and a semiparametric two-step model. More details for the randomized setting are available in: Knowlton, R., Tian, L., & Parast, L. (2025). "A General Framework to Assess Complex Heterogeneity in the Strength of a Surrogate Marker," Statistics in Medicine, 44(5), e70001 <doi:10.1002/sim.70001>. For an observational setting, functions in this package assess complex heterogeneity in the strength of a surrogate marker using meta-learners, with options for different base learners. More details for the observational setting will be available in the future in: Knowlton, R., Parast, L. (2025) "Assessing Surrogate Heterogeneity in Real World Data Using Meta-Learners." A tutorial for this package can be found at <https://www.laylaparast.com/cohetsurr>.

High dimensional discriminant analysis with compositional data is performed. The compositional data are first transformed using the alpha-transformation of Tsagris M., Preston S. and Wood A.T.A. (2011) <doi:10.48550/arXiv.1106.1451>, and then the High Dimensional Discriminant Analysis (HDDA) algorithm of Bouveyron C. Girard S. and Schmid C. (2007) <doi:10.1080/03610920701271095> is applied.

Cases are matched to controls in an efficient, optimal and computationally flexible way. It uses the idea of sub-sampling in the level of the case, by creating pseudo-observations of controls. The user can select between replacement and without replacement, the number of controls, and several covariates to match upon. See Mamouris (2021) <doi:10.1186/s12874-021-01256-3> for an overview.

Method for identifying the instar of Curculionid larvae from the observed distribution of the headcapsule size of mature larvae.

Computer algebra via the SymPy library (<https://www.sympy.org/>). This makes it possible to solve equations symbolically, find symbolic integrals, symbolic sums and other important quantities.

Enables creation of visualizations using the CanvasXpress framework in R. CanvasXpress is a standalone JavaScript library for reproducible research with complete tracking of data and end-user modifications stored in a single PNG image that can be played back. See <https://www.canvasxpress.org> for more information.

This package provides functions to construct finite-sample calibrated predictive intervals for Bayesian models, following the approach in Barber et al. (2021) <doi:10.1214/20-AOS1965>. These intervals are calculated efficiently using importance sampling for the leave-one-out residuals. By default, the intervals will also reflect the relative uncertainty in the Bayesian model, using the locally-weighted conformal methods of Lei et al. (2018) <doi:10.1080/01621459.2017.1307116>.

Enable seamless interaction with Consibio Cloud <https://consibio.cloud> API <https://api.v2.consibio.com/api-docs/>. This package provides tools to query data from resources like projects, elements, devices, and datalogs.

This package contains functions to detect and visualise periods of climate sensitivity (climate windows) for a given biological response. Please see van de Pol et al. (2016) <doi:10.1111/2041-210X.12590> and Bailey and van de Pol (2016) <doi:10.1371/journal.pone.0167980> for details.

Although discrete choice (choice-based conjoint) analysis has become a widely used technique for the elicitation of consumer preferences and hence a foundation for product design, to the best of our knowledge, there exists neither free and open-source nor commercial software that covers the game-theoretic simulation of competitive reactions among firms based on discrete choice models to improve decision making beyond traditional product (line) optimization. The package does not only provide functions to fill this gap but comprises an entire simulation pipeline including the upstream processes of discrete choice analysis itself. It ranges from preference generation, choice design, design assessment, error and response simulation, through hierarchical Bayesian estimation of mixed logit models as well as convergence and model assessment, to Nash equilibrium computation. Doing so, it partly draws from established packages concerned with discrete choice analysis. While its structure generally aims towards end-to-end simulation as well as simulation of competitive dynamics based on real data, all its key elements mentioned above may be of use independently of each other. For implementation and application details, see Dressler et al. (2026) <doi:10.48550/arXiv.2606.15593>.

This package implements the instruments for complex-valued modelling, including time series analysis and forecasting. This is based on the monograph by Svetunkov & Svetunkov (2024) <doi: 10.1007/978-3-031-62608-1>.

Fits a variety of cure models using excess hazard modeling methodology such as the mixture model proposed by Phillips et al. (2002) <doi:10.1002/sim.1101> The Weibull distribution is used to represent the survival function of the uncured patients; Fits also non-mixture cure model such as the time-to-null excess hazard model proposed by Boussari et al. (2020) <doi:10.1111/biom.13361>.

Given a patient-sharing network, calculate either the classic care density as proposed by Pollack et al. (2013) <doi:10.1007/s11606-012-2104-7> or the fragmented care density as proposed by Engels et al. (2024) <doi:10.1186/s12874-023-02106-0>. By utilizing the igraph and data.table packages, the provided functions scale well for very large graphs.

Execute Nonlinear Mixed Effects (NLME) models for pharmacometrics using a shiny interface. Specify engine parameters and select from different run options, including simple estimation, stepwise covariate search, bootstrapping, simulation, visual predictive check, and more. Models are executed using the Certara.RsNLME package.

Implementation of the Coarsened Exact Matching algorithm discussed along with its properties in Iacus, King, Porro (2011) <DOI:10.1198/jasa.2011.tm09599>; Iacus, King, Porro (2012) <DOI:10.1093/pan/mpr013> and Iacus, King, Porro (2019) <DOI:10.1017/pan.2018.29>.

This package provides a unified toolkit for cointegration testing including Fourier-based cointegration tests (FADL, FEG, FEG2, Tsong) that accommodate smooth structural breaks via flexible Fourier terms, and panel CADF cointegration tests with structural breaks using the Common Correlated Effects (CCE) estimator following Banerjee, Arcabic and Lee (2017) <doi:10.1016/j.econmod.2017.03.004>, Tsong, Lee, Tsai and Hu (2016) <doi:10.1007/s00181-015-1028-6>, and Banerjee and Carrion-i-Silvestre (2025) <doi:10.1080/07350015.2024.2327844>.

Reads and writes CSV with selected conventions. Uses the same generic function for reading and writing to promote consistent formats.