Given a protein multiple sequence alignment, it is a daunting task to assess the effects of substitutions along sequence length. The aaSEA package is intended to help researchers to rapidly analyze property changes caused by single, multiple and correlated amino acid substitutions in proteins.

This package provides a collection of functions to create spatial weights matrix objects from polygon contiguities, from point patterns by distance and tessellations, for summarizing these objects, and for permitting their use in spatial data analysis, including regional aggregation by minimum spanning tree.

This package contains various tools for working with and evaluating cross-validated area under the ROC curve (AUC) estimators. The primary functions of the package are ci.cvAUC and ci.pooled.cvAUC, which report cross-validated AUC and compute confidence intervals for cross-validated AUC estimates based on influence curves for i.i.d. and pooled repeated measures data, respectively.

This package provides an implementation of many measures for the assessment of the stability of feature selection. Both simple measures and measures which take into account the similarities between features are available.

This package provides a %dopar% adapter such that any type of futures can be used as backends for the foreach framework.

This package provides miscellaneous functions commonly used in other packages maintained by Yihui Xie.

Visualise complex relations in texts. This is done by providing functionalities for displaying text co-occurrence networks, text correlation networks, dependency relationships as well as text clustering. Feel free to join the effort of providing interesting text visualisations.

Feature Selection with Regularized Random Forest. This package is based on the randomForest package by Andy Liaw. The key difference is the RRF() function that builds a regularized random forest. Fortran original by Leo Breiman and Adele Cutler, R port by Andy Liaw and Matthew Wiener, Regularized random forest for classification by Houtao Deng, Regularized random forest for regression by Xin Guan. Reference: Houtao Deng (2013) <doi:10.48550/arXiv.1306.0237>.

This package provides functions to export graphics drawn with package grid to SVG format. Extra functions provide access to SVG features that are not available in standard R graphics, such as hyperlinks, animation, filters, masks, clipping paths, and gradient and pattern fills.

This package provides an improved heatmap package. It is completely compatible with the original R function heatmap, and provides more powerful and convenient features.

oai provides a general purpose client to work with any Open Archives Initiative Protocol for 'Metadata' Harvesting (OAI-PMH) service. Functions are provided to work with the OAI-PMH verbs: GetRecord, Identify, ListIdentifiers, ListMetadataFormats, ListRecords, and ListSets.

This package provides various methods for MRI tissue classification.

This is a deprecated package for accessing huge amounts of data. Cross-platform alternatives are the following packages: bigmemory (CRAN), ff (CRAN), or BufferedMatrix (Bioconductor). The main usage of it was inside the aroma.affymetrix package.

Create interactive ggplot2 graphics using htmlwidgets.

This package provides an interface to Amazon Web Services machine learning services, including SageMaker managed machine learning service, natural language processing, speech recognition, translation, and more.

This package provides coroutines for R, a family of functions that can be suspended and resumed later on. This includes async functions (which await) and generators (which yield). Async functions are based on the concurrency framework of the promises package. Generators are based on a dependency free iteration protocol defined in coro and are compatible with iterators from the reticulate package.

Algorithms to find arrangements of non-overlapping circles.

This package provides a dependency manager for R projects that allows you to manage the R packages your project depends on in an isolated, portable, and reproducible way.

This package provides counterparts to R string manipulation functions that account for the effects of ANSI text formatting control sequences.

Alternating least squares is often used to resolve components contributing to data with a bilinear structure; the basic technique may be extended to alternating constrained least squares. This package provides an implementation of multivariate curve resolution alternating least squares (MCR-ALS).

Commonly applied constraints include unimodality, non-negativity, and normalization of components. Several data matrices may be decomposed simultaneously by assuming that one of the two matrices in the bilinear decomposition is shared between datasets.

This is a package for curve, surface and function fitting with an emphasis on splines, spatial data and spatial statistics. The major methods include cubic, and thin plate splines, Kriging, and compactly supported covariance functions for large data sets.

This package contains a function that imports data from a CSV file, or uses manually entered data from the format (x, y, weight) and plots the appropriate ACC vs LOI graph and LMA graph. The main function is plotLMA (source file, header) that takes a data set and plots the appropriate LMA and ACC graphs. If no source file (a string) was passed, a manual data entry window is opened. The header parameter indicates by TRUE/FALSE (false by default) if the source CSV file has a header row or not. The dataset should contain only one independent variable (x) and one dependent variable (y) and can contain a weight for each observation.

Fit generalized linear models with binomial responses using either an adjusted-score approach to bias reduction or maximum penalized likelihood where penalization is by Jeffreys invariant prior. These procedures return estimates with improved frequentist properties (bias, mean squared error) that are always finite even in cases where the maximum likelihood estimates are infinite (data separation). Fitting takes place by fitting generalized linear models on iteratively updated pseudo-data. The interface is essentially the same as glm. More flexibility is provided by the fact that custom pseudo-data representations can be specified and used for model fitting. Functions are provided for the construction of confidence intervals for the reduced-bias estimates.

This package provides functions for simple fixed and random effects meta-analysis for two-sample comparisons and cumulative meta-analyses. It draws standard summary plots, funnel plots, and computes summaries and tests for association and heterogeneity.