Automatic generation of finite state machine models of dynamic decision-making that both have strong predictive power and are interpretable in human terms. We use an efficient model representation and a genetic algorithm-based estimation process to generate simple deterministic approximations that explain most of the structure of complex stochastic processes. We have applied the software to empirical data, and demonstrated it's ability to recover known data-generating processes by simulating data with agent-based models and correctly deriving the underlying decision models for multiple agent models and degrees of stochasticity.

Dynamic stochastic block model that combines a stochastic block model (SBM) for its static part with independent Markov chains for the evolution of the nodes groups through time, developed in Matias and Miele (2016) <doi:10.1111/rssb.12200>.

Individual gene expression patterns are encoded into a series of eigenvector patterns ('WGCNA package). Using the framework of linear model-based differential expression comparisons ('limma package), time-course expression patterns for genes in different conditions are compared and analyzed for significant pattern changes. For reference, see: Greenham K, Sartor RC, Zorich S, Lou P, Mockler TC and McClung CR. eLife. 2020 Sep 30;9(4). <doi:10.7554/eLife.58993>.

Set of functions for Data Envelopment Analysis, including classical, fuzzy, cross-efficiency, bootstrapping, and Malmquist models. See: Banker, R.; Charnes, A.; Cooper, W.W. (1984). <doi:10.1287/mnsc.30.9.1078>, Charnes, A.; Cooper, W.W.; Rhodes, E. (1978). <doi:10.1016/0377-2217(78)90138-8> and Charnes, A.; Cooper, W.W.; Rhodes, E. (1981). <doi:10.1287/mnsc.27.6.668>.

This package implements a Bayesian Optimal Phase II design (DTE-BOP2) for trials with delayed treatment effects, particularly relevant to immunotherapy studies where treatment benefits may emerge after a delay. The method builds upon the BOP2 framework and incorporates uncertainty in the delay timepoint through a truncated gamma prior, informed by expert knowledge or default settings. Supports two-arm trial designs with functionality for sample size determination, interim and final analyses, and comprehensive simulation under various delay and design scenarios. Ensures rigorous type I and II error control while improving trial efficiency and power when the delay effect is present. A manuscript describing the methodology is under development and will be formally referenced upon publication.

Implement some deep learning architectures and neural network algorithms, including BP,RBM,DBN,Deep autoencoder and so on.

As a distributed imputation strategy, the Distributed full information Multiple Imputation method is developed to impute missing response variables in distributed linear regression. The philosophy of the package is described in Guo (2025) <doi:10.1038/s41598-025-93333-6>.

The goal of dynamicpv is to provide a simple way to calculate (net) present values and outputs from health economic models (especially cost-effectiveness and budget impact) in discrete time that reflect dynamic pricing and dynamic uptake. Dynamic pricing is also known as life cycle pricing; dynamic uptake is also known as multiple or stacked cohorts, or dynamic disease prevalence. Shafrin (2024) <doi:10.1515/fhep-2024-0014> provides an explanation of dynamic value elements, in the context of Generalized Cost Effectiveness Analysis, and Puls (2024) <doi:10.1016/j.jval.2024.03.006> reviews challenges of incorporating such dynamic value elements. This package aims to reduce those challenges.

Access and manage the application programming interface (API) of the United Nations Office for the Coordination of Humanitarian Affairs (OCHA) ReliefWeb disaster events at <https://reliefweb.int/disasters>. The package requires a minimal number of dependencies. It offers functionality to retrieve a user-defined sample of disaster events from ReliefWeb, providing an easy alternative to scraping the ReliefWeb website. It enables a seamless integration of regular data updates into the research work flow.

This R function implements the nonstationary Kriging model proposed by Tuo, Wu and Yu (2014) <DOI:10.1080/00401706.2013.842935> for analyzing multi-fidelity computer outputs. This function computes the maximum likelihood estimates for the model parameters as well as the predictive means and variances of the exact solution.

Differential geometric least angle regression method for fitting sparse generalized linear models. In this version of the package, the user can fit models specifying Gaussian, Poisson, Binomial, Gamma and Inverse Gaussian family. Furthermore, several link functions can be used to model the relationship between the conditional expected value of the response variable and the linear predictor. The solution curve can be computed using an efficient predictor-corrector or a cyclic coordinate descent algorithm, as described in the paper linked to via the URL below.

Computes a new measure, DNSL betweenness, via the creation of a new graph from an existing one, duplicating nodes with self-loops. This betweenness centrality does not drop this essential information. Implements Merelo & Molinari (2024) <doi:10.1007/s42001-023-00245-4>.

Model cell type heterogeneity of bulk renal cell carcinoma. The observed gene expression in bulk tumor sample is modeled by a log-normal distribution with the location parameter structured as a linear combination of the component-specific gene expressions.

An R DataBase Interface ('DBI') compatible interface to various database platforms ('PostgreSQL', Oracle', Microsoft SQL Server', Amazon Redshift', Microsoft Parallel Database Warehouse', IBM Netezza', Apache Impala', Google BigQuery', Snowflake', Spark', SQLite', and InterSystems IRIS'). Also includes support for fetching data as Andromeda objects. Uses either Java Database Connectivity ('JDBC') or other DBI drivers to connect to databases.

Compares the fit of alternative models of continuous trait differentiation between sister species and other paired lineages. Differences in trait means between two lineages arise as they diverge from a common ancestor, and alternative processes of evolutionary divergence are expected to leave unique signatures in the distribution of trait differentiation in datasets comprised of many lineage pairs. Models include approximations of divergent selection, drift, and stabilizing selection. A variety of model extensions facilitate the testing of process-to-pattern hypotheses. Users supply trait data and divergence times for each lineage pair. The fit of alternative models is compared in a likelihood framework.

Utilities for handling dates and times, such as selecting particular days of the week or month, formatting timestamps as required by RSS feeds, or converting timestamp representations of other software (such as MATLAB and Excel') to R. The package is lightweight (no dependencies, pure R implementations) and relies only on R's standard classes to represent dates and times ('Date and POSIXt'); it aims to provide efficient implementations, through vectorisation and the use of R's native numeric representations of timestamps where possible.

Traditional phasing programs are limited to diploid organisms. Our method modifies Li and Stephens algorithm with Markov chain Monte Carlo (MCMC) approaches, and builds a generic framework that allows haplotype searches in a multiple infection setting. This package is primarily developed as part of the Pf3k project, which is a global collaboration using the latest sequencing technologies to provide a high-resolution view of natural variation in the malaria parasite Plasmodium falciparum. Parasite DNA are extracted from patient blood sample, which often contains more than one parasite strain, with unknown proportions. This package is used for deconvoluting mixed haplotypes, and reporting the mixture proportions from each sample.

Displays a terrible joke, the kind only dads crack.

Parse, format, and validate international phone numbers using Google's libphonenumber java library, <https://github.com/google/libphonenumber>.

This package contains one main function deduped() which speeds up slow, vectorized functions by only performing computations on the unique values of the input and expanding the results at the end.

This package performs Diffusion Non-Additive (DNA) model proposed by Heo, Boutelet, and Sung (2025+) <doi:10.48550/arXiv.2506.08328> for multi-fidelity computer experiments with tuning parameters. The DNA model captures nonlinear dependencies across fidelity levels using Gaussian process priors and is particularly effective when simulations at different fidelity levels are nonlinearly correlated. The DNA model targets not only interpolation across given fidelity levels but also extrapolation to smaller tuning parameters including the exact solution corresponding to a zero-valued tuning parameter, leveraging a nonseparable covariance kernel structure that models interactions between the tuning parameter and input variables. Closed-form expressions for the predictive mean and variance enable efficient inference and uncertainty quantification. Hyperparameters in the model are estimated via maximum likelihood estimation.

This package contains data organized by topics: categorical data, regression model, means comparisons, independent and repeated measures ANOVA, mixed ANOVA and ANCOVA.

An implementation of the differentiable lasso (dlasso) and SCAD (dSCAD) using iterative ridge algorithm. This package allows selecting the tuning parameter by AIC, BIC, GIC and GIC.

This package provides a collection of functions for directional data (including massive data, with millions of observations) analysis. Hypothesis testing, discriminant and regression analysis, MLE of distributions and more are included. The standard textbook for such data is the "Directional Statistics" by Mardia, K. V. and Jupp, P. E. (2000). Other references include: a) Paine J.P., Preston S.P., Tsagris M. and Wood A.T.A. (2018). "An elliptically symmetric angular Gaussian distribution". Statistics and Computing 28(3): 689-697. <doi:10.1007/s11222-017-9756-4>. b) Tsagris M. and Alenazi A. (2019). "Comparison of discriminant analysis methods on the sphere". Communications in Statistics: Case Studies, Data Analysis and Applications 5(4):467--491. <doi:10.1080/23737484.2019.1684854>. c) Paine J.P., Preston S.P., Tsagris M. and Wood A.T.A. (2020). "Spherical regression models with general covariates and anisotropic errors". Statistics and Computing 30(1): 153--165. <doi:10.1007/s11222-019-09872-2>. d) Tsagris M. and Alenazi A. (2024). "An investigation of hypothesis testing procedures for circular and spherical mean vectors". Communications in Statistics-Simulation and Computation, 53(3): 1387--1408. <doi:10.1080/03610918.2022.2045499>. e) Yu Z. and Huang X. (2024). A new parameterization for elliptically symmetric angular Gaussian distributions of arbitrary dimension. Electronic Journal of Statistics, 18(1): 301--334. <doi:10.1214/23-EJS2210>. f) Tsagris M. and Alzeley O. (2025). "Circular and spherical projected Cauchy distributions: A Novel Framework for Circular and Directional Data Modeling". Australian & New Zealand Journal of Statistics, 67(1): 77--103. <doi:10.1111/anzs.12434>. g) Tsagris M., Papastamoulis P. and Kato S. (2025). "Directional data analysis: spherical Cauchy or Poisson kernel-based distribution". Statistics and Computing, 35:51. <doi:10.1007/s11222-025-10583-0>.