This package provides tools for spatially explicit capture-recapture analysis of animal populations in linear habitats, extending package secr'.

Include interactive sparkline charts <http://omnipotent.net/jquery.sparkline> in all R contexts with the convenience of htmlwidgets'.

Translates antibody levels measured in cross-sectional population samples into estimates of the frequency with which seroconversions (infections) occur in the sampled populations. Replaces the previous `seroincidence` package.

This package provides a toolbox that allows the user to implement accessibility related concepts.

Manage a collection/library of R source packages. Discover, document, load, test source packages. Enable to use those packages as if they were actually installed. Quickly reload only what is needed on source code change. Run tests and checks in parallel.

This package provides utilities to create or suppress start-up messages.

Generates cell-level cytokine activity estimates using relevant information from gene sets constructed with the CytoSig and the Reactome databases and scored using the modified Variance-adjusted Mahalanobis (VAM) framework for single-cell RNA-sequencing (scRNA-seq) data. CytoSig database is described in: Jiang at al., (2021) <doi:10.1038/s41592-021-01274-5>. Reactome database is described in: Gillespie et al., (2021) <doi:10.1093/nar/gkab1028>. The VAM method is outlined in: Frost (2020) <doi:10.1093/nar/gkaa582>.

The SPARRA risk score (Scottish Patients At Risk of admission and Re-Admission) estimates yearly risk of emergency hospital admission using electronic health records on a monthly basis for most of the Scottish population. This package implements a suite of functions used to analyse the behaviour and performance of the score, focusing particularly on differential performance over demographically-defined groups. It includes useful utility functions to plot receiver-operator-characteristic, precision-recall and calibration curves, draw stock human figures, estimate counterfactual quantities without the need to re-compute risk scores, to simulate a semi-realistic dataset. Our manuscript can be found at: <doi:10.1371/journal.pdig.0000675>.

This package provides a group of functions that support the sf package, focused primarily on repairing polygons that break when re-projected.

This package implements the Stable Balancing Weights by Zubizarreta (2015) <DOI:10.1080/01621459.2015.1023805>. These are the weights of minimum variance that approximately balance the empirical distribution of the observed covariates. For an overview, see Chattopadhyay, Hase and Zubizarreta (2020) <DOI:10.1002/sim.8659>. To solve the optimization problem in sbw', the default solver is quadprog', which is readily available through CRAN. The solver osqp is also posted on CRAN. To enhance the performance of sbw', users are encouraged to install other solvers such as gurobi and Rmosek', which require special installation. For the installation of gurobi and pogs, please follow the instructions at <https://docs.gurobi.com/projects/optimizer/en/current/reference/r.html> and <http://foges.github.io/pogs/stp/r>.

Sometimes it is useful to serve up alternative shiny UIs depending on information passed in the request object, such as the value of a cookie or a query parameter. This packages facilitates such switches.

This package provides a tool for simulating rhythmic data: transcriptome data using Gaussian or negative binomial distributions, and behavioral activity data using Bernoulli or Poisson distributions. See Singer et al. (2019) <doi:10.7717/peerj.6985>.

The saemix package implements the Stochastic Approximation EM algorithm for parameter estimation in (non)linear mixed effects models. It (i) computes the maximum likelihood estimator of the population parameters, without any approximation of the model (linearisation, quadrature approximation,...), using the Stochastic Approximation Expectation Maximization (SAEM) algorithm, (ii) provides standard errors for the maximum likelihood estimator (iii) estimates the conditional modes, the conditional means and the conditional standard deviations of the individual parameters, using the Hastings-Metropolis algorithm (see Comets et al. (2017) <doi:10.18637/jss.v080.i03>). Many applications of SAEM in agronomy, animal breeding and PKPD analysis have been published by members of the Monolix group. The full PDF documentation for the package including references about the algorithm and examples can be downloaded on the github of the IAME research institute for saemix': <https://github.com/iame-researchCenter/saemix/blob/7638e1b09ccb01cdff173068e01c266e906f76eb/docsaem.pdf>.

Estimates the restricted mean survival time (RMST) with the time window [0, tau], where tau is adaptively selected from the procedure, proposed by Horiguchi et al. (2018) <doi:10.1002/sim.7661>. It also estimates the RMST with the time window [tau1, tau2], where tau1 is adaptively selected from the procedure, proposed by Horiguchi et al. (2023) <doi:10.1002/sim.9662>.

The sparse online principal component can not only process the online data set, but also obtain a sparse solution of the online data set. The philosophy of the package is described in Guo G. (2022) <doi:10.1007/s00180-022-01270-z>.

The fossil record is a joint expression of ecological, taphonomic, evolutionary, and stratigraphic processes (Holland and Patzkowsky, 2012, ISBN:978-0226649382). This package allowing to simulate biological processes in the time domain (e.g., trait evolution, fossil abundance, phylogenetic trees), and examine how their expression in the rock record (stratigraphic domain) is influenced based on age-depth models, ecological niche models, and taphonomic effects. Functions simulating common processes used in modeling trait evolution, biostratigraphy or event type data such as first/last occurrences are provided and can be used standalone or as part of a pipeline. The package comes with example data sets and tutorials in several vignettes, which can be used as a template to set up one's own simulation.

This package provides tools to efficiently analyze and visualize laboratory data from aqueous static adsorption experiments. The package provides functions to plot Langmuir, Freundlich, and Temkin isotherms and functions to determine the statistical conformity of data points to the Langmuir, Freundlich, and Temkin adsorption models through statistical characterization of the isothermic least squares regressions lines. Scientific Reference: Dada, A.O, Olalekan, A., Olatunya, A. (2012) <doi:10.9790/5736-0313845>.

This package creates 3D animated, interactive visualizations that can be viewed in a web browser.

This package implements sparse Bayesian learning method for QTL mapping and genome-wide association studies.

Forms queries to submit to the Cleveland Federal Reserve Bank web site's financial stress index data site. Provides query functions for both the composite stress index and the components data. By default the download includes daily time series data starting September 25, 1991. The functions return a class of either type easing or cfsi which contain a list of items related to the query and its graphical presentation. The list includes the time series data as an xts object. The package provides four lattice time series plots to render the time series data in a manner similar to the bank's own presentation.

Aggregates large single-cell data into metacell dataset by merging together gene expression of very similar cells. SuperCell uses velocyto.R <doi:10.1038/s41586-018-0414-6> <https://github.com/velocyto-team/velocyto.R> for RNA velocity. We also recommend installing scater Bioconductor package <doi:10.18129/B9.bioc.scater> <https://bioconductor.org/packages/release/bioc/html/scater.html>.

Computation of sparse eigenvectors of a matrix (aka sparse PCA) with running time 2-3 orders of magnitude lower than existing methods and better final performance in terms of recovery of sparsity pattern and estimation of numerical values. Can handle covariance matrices as well as data matrices with real or complex-valued entries. Different levels of sparsity can be specified for each individual ordered eigenvector and the method is robust in parameter selection. See vignette for a detailed documentation and comparison, with several illustrative examples. The package is based on the paper: K. Benidis, Y. Sun, P. Babu, and D. P. Palomar (2016). "Orthogonal Sparse PCA and Covariance Estimation via Procrustes Reformulation," IEEE Transactions on Signal Processing <doi:10.1109/TSP.2016.2605073>.

This package provides a database-independent JDBC interface.

Conduct asymptotic and empirical power and sample size calculations for Single-Nucleotide Polymorphism (SNP) association studies with right censored time to event outcomes.