Bayesian survival model using Weibull regression on both scale and shape parameters. Dependence of shape parameter on covariates permits deviation from proportional-hazard assumption, leading to dynamic - i.e. non-constant with time - hazard ratios between subjects. Bayesian Lasso shrinkage in the form of two Laplace priors - one for scale and one for shape coefficients - allows for many covariates to be included. Cross-validation helper functions can be used to tune the shrinkage parameters. Monte Carlo Markov Chain (MCMC) sampling using a Gibbs wrapper around Radford Neal's univariate slice sampler (R package MfUSampler) is used for coefficient estimation.

This package provides arithmetic functions for R matrix and big.matrix objects as well as functions for QR factorization, Cholesky factorization, General eigenvalue, and Singular value decomposition (SVD). A method matrix multiplication and an arithmetic method -for matrix addition, matrix difference- allows for mixed type operation -a matrix class object and a big.matrix class object- and pure type operation for two big.matrix class objects.

Provide a sparse matrix format with data stored on disk, to be used in both R and C++. This is intended for more efficient use of sparse data in C++ and also when parallelizing, since data on disk does not need copying. Only a limited number of features will be implemented. For now, conversion can be performed from a dgCMatrix or a dsCMatrix from R package Matrix'. A new compact format is also now available.

This package implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis. Such an interim analysis can either be blinded or unblinded. Code is provided for Normally distributed endpoints with known variance, with a prominent example being the hazard ratio.

This package provides functions are pre-configured to utilize Bootstrap 5 classes and HTML structures to create Bootstrap-styled HTML quickly and easily. Includes functions for creating common Bootstrap elements such as containers, rows, cols, navbars, etc. Intended to be used with the html5 package. Learn more at <https://getbootstrap.com/>.

This package implements Bayesian Lasso regression using efficient Gibbs sampling algorithms, including modified versions of the Hans and Park Casella (PC) samplers. Includes functions for working with the Lasso distribution, such as its density, cumulative distribution, quantile, and random generation functions, along with moment calculations. Also includes a function to compute the Mills ratio. Designed for sparse linear models and suitable for high-dimensional regression problems.

Making probabilistic projections of total fertility rate for all countries of the world, using a Bayesian hierarchical model <doi:10.1007/s13524-011-0040-5> <doi:10.18637/jss.v106.i08>. Subnational probabilistic projections are also supported <doi:10.4054/DemRes.2018.38.60>.

Four methods for mediation analysis with missing data: Listwise deletion, Pairwise deletion, Multiple imputation, and Two Stage Maximum Likelihood algorithm. For MI and TS-ML, auxiliary variables can be included. Bootstrap confidence intervals for mediation effects are obtained. The robust method is also implemented for TS-ML. Since version 1.4, bmem adds the capability to conduct power analysis for mediation models. Details about the methods used can be found in these articles. Zhang and Wang (2003) <doi:10.1007/s11336-012-9301-5>. Zhang (2014) <doi:10.3758/s13428-013-0424-0>.

Selection of informative features like genes, transcripts, RNA seq, etc. using Bootstrap Maximum Relevance and Minimum Redundancy technique from a given high dimensional genomic dataset. Informative gene selection involves identification of relevant genes and removal of redundant genes as much as possible from a large gene space. Main applications in high-dimensional expression data analysis (e.g. microarray data, NGS expression data and other genomics and proteomics applications).

Full implementation of the 28 distributions introduced as benchmarks for nonparametric density estimation by Berlinet and Devroye (1994) <https://hal.science/hal-03659919>. Includes densities, cdfs, quantile functions and generators for samples as well as additional information on features of the densities. Also contains the 4 histogram densities used in Rozenholc/Mildenberger/Gather (2010) <doi:10.1016/j.csda.2010.04.021>.

Efficient simulation of Brownian semistationary (BSS) processes using the hybrid simulation scheme, as described in Bennedsen, Lunde, Pakkannen (2017) <arXiv:1507.03004v4>, as well as functions to fit BSS processes to data, and functions to estimate the stochastic volatility process of a BSS process.

This package provides deterministic two- and three-dimensional boids and swarm simulations for R. The package implements Reynolds-style separation, alignment, and cohesion rules with optional obstacles, attractors, predators, species parameters, and reproducible frame export. Simulation state is renderer-neutral; optional adapters can hand frame data to visualization packages such as ggWebGL'. The model follows Reynolds (1987) <doi:10.1145/37402.37406>.

Includes algorithms to assess alpha and beta diversity in all their dimensions (taxonomic, phylogenetic and functional). It allows performing a number of analyses based on species identities/abundances, phylogenetic/functional distances, trees, convex-hulls or kernel density n-dimensional hypervolumes depicting species relationships. Cardoso et al. (2015) <doi:10.1111/2041-210X.12310>.

Implementation of the Generalized Pairwise Comparisons (GPC) as defined in Buyse (2010) <doi:10.1002/sim.3923> for complete observations, and extended in Peron (2018) <doi:10.1177/0962280216658320> to deal with right-censoring. GPC compare two groups of observations (intervention vs. control group) regarding several prioritized endpoints to estimate the probability that a random observation drawn from one group performs better/worse/equivalently than a random observation drawn from the other group. Summary statistics such as the net treatment benefit, win ratio, or win odds are then deduced from these probabilities. Confidence intervals and p-values are obtained based on asymptotic results (Ozenne 2021 <doi:10.1177/09622802211037067>), non-parametric bootstrap, or permutations. The software enables the use of thresholds of minimal importance difference, stratification, non-prioritized endpoints (O Brien test), and can handle right-censoring and competing-risks.

Fit beta calibration models and obtain calibrated probabilities from them.

Collection of tools to make R more convenient. Includes tools to summarize data using statistics not available with base R and manipulate objects for analyses.

We use a Bayesian approach to run individual patient data meta-analysis and network meta-analysis using JAGS'. The methods incorporate shrinkage methods and calculate patient-specific treatment effects as described in Seo et al. (2021) <DOI:10.1002/sim.8859>. This package also includes user-friendly functions that impute missing data in an individual patient data using mice-related packages.

Generation of samples from a mix of binary, ordinal and continuous random variables with a pre-specified correlation matrix and marginal distributions. The details of the method are explained in Demirtas et al. (2012) <DOI:10.1002/sim.5362>.

Bootstrap resampling methods have been widely studied in the context of survey data. This package implements various bootstrap resampling techniques tailored for survey data, with a focus on stratified simple random sampling and stratified two-stage cluster sampling. It provides tools for precise and consistent bootstrap variance estimation for population totals, means, and quartiles. Additionally, it enables easy generation of bootstrap samples for in-depth analysis.

Some elementary matrix algebra tools are implemented to manage block matrices or partitioned matrix, i.e. "matrix of matrices" (http://en.wikipedia.org/wiki/Block_matrix). The block matrix is here defined as a new S3 object. In this package, some methods for "matrix" object are rewritten for "blockmatrix" object. New methods are implemented. This package was created to solve equation systems with block matrices for the analysis of environmental vector time series . Bugs/comments/questions/collaboration of any kind are warmly welcomed.

This package provides tools for 3D imaging, mostly for biology/microscopy. Read and write TIFF stacks. Functions for segmentation, filtering and analyzing 3D point patterns.

This project aims to enable the method of Path Analysis to infer causalities from data. For this we propose a hybrid approach, which uses Bayesian network structure learning algorithms from data to create the input file for creation of a PA model. The process is performed in a semi-automatic way by our intermediate algorithm, allowing novice researchers to create and evaluate their own PA models from a data set. The references used for this project are: Koller, D., & Friedman, N. (2009). Probabilistic graphical models: principles and techniques. MIT press. <doi:10.1017/S0269888910000275>. Nagarajan, R., Scutari, M., & Lèbre, S. (2013). Bayesian networks in r. Springer, 122, 125-127. Scutari, M., & Denis, J. B. <doi:10.1007/978-1-4614-6446-4>. Scutari M (2010). Bayesian networks: with examples in R. Chapman and Hall/CRC. <doi:10.1201/b17065>. Rosseel, Y. (2012). lavaan: An R Package for Structural Equation Modeling. Journal of Statistical Software, 48(2), 1 - 36. <doi:10.18637/jss.v048.i02>.

This package provides a set of functions to help clinical trial researchers calculate power and sample size for two-arm Bayesian randomized clinical trials that do or do not incorporate historical control data. At some point during the design process, a clinical trial researcher who is designing a basic two-arm Bayesian randomized clinical trial needs to make decisions about power and sample size within the context of hypothesized treatment effects. Through simulation, the simple_sim() function will estimate power and other user specified clinical trial characteristics at user specified sample sizes given user defined scenarios about treatment effect,control group characteristics, and outcome. If the clinical trial researcher has access to historical control data, then the researcher can design a two-arm Bayesian randomized clinical trial that incorporates the historical data. In such a case, the researcher needs to work through the potential consequences of historical and randomized control differences on trial characteristics, in addition to working through issues regarding power in the context of sample size, treatment effect size, and outcome. If a researcher designs a clinical trial that will incorporate historical control data, the researcher needs the randomized controls to be from the same population as the historical controls. What if this is not the case when the designed trial is implemented? During the design phase, the researcher needs to investigate the negative effects of possible historic/randomized control differences on power, type one error, and other trial characteristics. Using this information, the researcher should design the trial to mitigate these negative effects. Through simulation, the historic_sim() function will estimate power and other user specified clinical trial characteristics at user specified sample sizes given user defined scenarios about historical and randomized control differences as well as treatment effects and outcomes. The results from historic_sim() and simple_sim() can be printed with print_table() and graphed with plot_table() methods. Outcomes considered are Gaussian, Poisson, Bernoulli, Lognormal, Weibull, and Piecewise Exponential. The methods are described in Eggleston et al. (2021) <doi:10.18637/jss.v100.i21>.

Fetches monthly financial tables and banking sector data published on the official website of the Banking Regulation and Supervision Agency of Turkey and also enables you to save it as an Excel file. It is a R implementation of the Python package <https://pypi.org/project/bddkdata/>.