Builds a LASSO, Ridge, or Elastic Net model with glmnet or cv.glmnet with bootstrap inference statistics (SE, CI, and p-value) for selected coefficients with no shrinkage applied for them. Model performance can be evaluated on test data and an automated alpha selection is implemented for Elastic Net. Parallelized computation is used to speed up the process. The methods are described in Friedman et al. (2010) <doi:10.18637/jss.v033.i01> and Simon et al. (2011) <doi:10.18637/jss.v039.i05>.

This package provides a comprehensive suite of helper functions designed to facilitate the analysis of genomic annotations from the GENCODE database <https://www.gencodegenes.org/>, supporting both human and mouse genomes. This toolkit enables users to extract, filter, and analyze a wide range of annotation features including genes, transcripts, exons, and introns across different GENCODE releases. It provides functionality for cross-version comparisons, allowing researchers to systematically track annotation updates, structural changes, and feature-level differences between releases. In addition, the package can generate high-quality FASTA files containing donor and acceptor splice site motifs, which are formatted for direct input into the MaxEntScan tool (Yeo and Burge, 2004 <doi:10.1089/1066527041410418>), enabling accurate calculation of splice site strength scores.

This package implements the most common Gaussian process (GP) models using Laplace and expectation propagation (EP) approximations, maximum marginal likelihood (or posterior) inference for the hyperparameters, and sparse approximations for larger datasets.

The program GRNN implements the algorithm proposed by Specht (1991).

This is a set of functions to retrieve information about GIMMS NDVI3g files currently available online; download (and re-arrange, in the case of NDVI3g.v0) the half-monthly data sets; import downloaded files from ENVI binary (NDVI3g.v0) or NetCDF format (NDVI3g.v1) directly into R based on the widespread raster package; conduct quality control; and generate monthly composites (e.g., maximum values) from the half-monthly input data. As a special gimmick, a method is included to conveniently apply the Mann-Kendall trend test upon Raster* images, optionally featuring trend-free pre-whitening to account for lag-1 autocorrelation.

We define generalized multipartite networks as the joint observation of several networks implying some common pre-specified groups of individuals. The aim is to fit an adapted version of the popular stochastic block model to multipartite networks, as described in Bar-hen, Barbillon and Donnet (2020) <arXiv:1807.10138>.

This package provides tools for applying the Bayesian Gower agreement methodology (presented in the package vignette) to nominal or ordinal data. The framework can accommodate any number of units, any number of coders, and missingness; and can handle both one-way and two-way random study designs. Influential units and/or coders can be identified easily using leave-one-out statistics.

Association analysis between categorical variables using the Goodman and Kruskal tau measure. This asymmetric association measure allows the detection of asymmetric relations between categorical variables (e.g., one variable obtained by re-grouping another).

Graceful ggplot'-based graphics and utility functions for working with generalized additive models (GAMs) fitted using the mgcv package. Provides a reimplementation of the plot() method for GAMs that mgcv provides, as well as tidyverse compatible representations of estimated smooths.

The GeneCycle package implements the approaches of Wichert et al. (2004) <doi:10.1093/bioinformatics/btg364>, Ahdesmaki et al. (2005) <doi:10.1186/1471-2105-6-117> and Ahdesmaki et al. (2007) <DOI:10.1186/1471-2105-8-233> for detecting periodically expressed genes from gene expression time series data.

Writes SAS code to get predicted values from every tree of a gbm.object.

This package provides the following types of models: Models for contingency tables (i.e. log-linear models) Graphical Gaussian models for multivariate normal data (i.e. covariance selection models) Mixed interaction models. Documentation about gRim is provided by vignettes included in this package and the book by Højsgaard, Edwards and Lauritzen (2012, <doi:10.1007/978-1-4614-2299-0>); see citation("gRim") for details.

Create network-style visualizations of pairwise relationships using custom edge glyphs built on top of ggplot2'. The package supports both statistical and non-statistical data and allows users to represent directed relationships. This enables clear, publication-ready graphics for exploring and communicating relational structures in a wide range of domains. The method was first used in Abu-Akel et al. (2021) <doi:10.1371/journal.pone.0245100>. Code is released under the MIT License; included datasets are licensed under the Creative Commons Attribution 4.0 International (CC BY 4.0).

Spatial stratified heterogeneity (SSH), referring to the within strata are more similar than the between strata, a model with global parameters would be confounded if input data is SSH. Note that the "spatial" here can be either geospatial or the space in mathematical meaning. Geographical detector is a novel tool to investigate SSH: (1) measure and find SSH of a variable Y; (2) test the power of determinant X of a dependent variable Y according to the consistency between their spatial distributions; and (3) investigate the interaction between two explanatory variables X1 and X2 to a dependent variable Y (Wang et al 2014 <doi:10.1080/13658810802443457>, Wang, Zhang, and Fu 2016 <doi:10.1016/j.ecolind.2016.02.052>).

This package provides a framework to detect Differential Item Functioning (DIF) in Generalized Partial Credit Models (GPCM) and special cases of the GPCM as proposed by Schauberger and Mair (2019) <doi:10.3758/s13428-019-01224-2>. A joint model is set up where DIF is explicitly parametrized and penalized likelihood estimation is used for parameter selection. The big advantage of the method called GPCMlasso is that several variables can be treated simultaneously and that both continuous and categorical variables can be used to detect DIF.

At Novartis, we aimed at standardizing the set of diagnostic plots used for modeling activities in order to reduce the overall effort required for generating such plots. For this, we developed a guidance that proposes an adequate set of diagnostics and a toolbox, called ggPMX to execute them. ggPMX is a toolbox that can generate all diagnostic plots at a quality sufficient for publication and submissions using few lines of code. This package focuses on plots recommended by ISoP <doi:10.1002/psp4.12161>. While not required, you can get/install the R lixoftConnectors package in the Monolix installation, as described at the following url <https://monolixsuite.slp-software.com/r-functions/2024R1/installation-and-initialization>. When lixoftConnectors is available, R can use Monolix directly to create the required Chart Data instead of exporting it from the Monolix gui.

Maps of France in 1830, multivariate datasets from A.-M. Guerry and others, and statistical and graphic methods related to Guerry's "Moral Statistics of France". The goal is to facilitate the exploration and development of statistical and graphic methods for multivariate data in a geospatial context of historical interest.

This General Regression Neural Networks Package uses various distance functions. It was motivated by Specht (1991, ISBN:1045-9227), and updated from previous published paper Li et al. (2016) <doi:10.1016/j.palaeo.2015.11.005>. This package includes various functions, although "euclidean" distance is used traditionally.

Summarises a collection of partitions into a single optimal partition. The objective function is the expected posterior loss, and the minimisation is performed through a greedy algorithm described in Rastelli, R. and Friel, N. (2017) "Optimal Bayesian estimators for latent variable cluster models" <DOI:10.1007/s11222-017-9786-y>.

This package provides functions to assess the goodness of fit of binary, multinomial and ordinal logistic models. Included are the Hosmer-Lemeshow tests (binary, multinomial and ordinal) and the Lipsitz and Pulkstenis-Robinson tests (ordinal).

This package provides classes for GeoJSON to make working with GeoJSON easier. Includes S3 classes for GeoJSON classes with brief summary output, and a few methods such as extracting and adding bounding boxes, properties, and coordinate reference systems; working with newline delimited GeoJSON'; and serializing to/from Geobuf binary GeoJSON format.

This package implements the GALAHAD algorithm (Geometry-Adaptive Lyapunov'-Assured Hybrid Optimizer), combining Riemannian metrics, Lyapunov stability checks, and trust-region methods for stable optimization of mixed-geometry parameters. Designed for biological modeling (germination, dose-response, survival) where rates, concentrations, and unconstrained variables coexist. Developed at the Minnesota Center for Prion Research and Outreach (MNPRO), University of Minnesota. Based on Conn et al. (2000) <doi:10.1137/1.9780898719857>, Amari (1998) <doi:10.1162/089976698300017746>, Beck & Teboulle (2003) <doi:10.1016/S0167-6377(02)00231-6>, Nesterov (2017) <https://www.jstor.org/stable/resrep30722>, and Walne et al. (2020) <doi:10.1002/agg2.20098>.

Estimates the Gini index and computes variances and confidence intervals for finite and infinite populations, using different methods; also computes Gini index for continuous probability distributions, draws samples from continuous probability distributions with Gini indices set by the user; uses Rcpp'. References: Muñoz et al. (2023) <doi:10.1177/00491241231176847>. à lvarez et al. (2021) <doi:10.3390/math9243252>. Giorgi and Gigliarano (2017) <doi:10.1111/joes.12185>. Langel and Tillé (2013) <doi:10.1111/j.1467-985X.2012.01048.x>.

An implementation of SPRE (standardised predicted random-effects) statistics in R to explore heterogeneity in genetic association meta- analyses, as described by Magosi et al. (2019) <doi:10.1093/bioinformatics/btz590>. SPRE statistics are precision weighted residuals that indicate the direction and extent with which individual study-effects in a meta-analysis deviate from the average genetic effect. Overly influential positive outliers have the potential to inflate average genetic effects in a meta-analysis whilst negative outliers might lower or change the direction of effect. See the getspres website for documentation and examples <https://magosil86.github.io/getspres/>.