This package provides tools for road-constrained, least-cost pedestrian evacuation modeling. The package provides reusable functions for preparing hazard zones, generating road-based evacuation origin points, identifying escape/safety points, creating slope-based conductance surfaces, calculating least-cost distance to safety, and converting distance outputs into evacuation-time polygons. It is designed to support workflows like tsunami evacuation modeling while remaining adaptable to other regions and hazards. Tsunami-specific helpers support separate land-only hazard zones, water-combined escape zones, road-aware escape boundaries, and study-area inset cropping for quality assurance and quality control. Methods build on Cordero et al. (2025) <doi:10.1007/s44367-025-00018-y>, Lewis (2021) <doi:10.1007/s10816-021-09522-w>, and Joseph Lewis's leastcostpath package (2023) <https://CRAN.R-project.org/package=leastcostpath>.

Genetic predisposition for complex traits is often manifested through multiple tissues of interest at different time points in the development. As an example, the genetic predisposition for obesity could be manifested through inherited variants that control metabolism through regulation of genes expressed in the brain and/or through the control of fat storage in the adipose tissue by dysregulation of genes expressed in adipose tissue. We present a method eGST (eQTL-based genetic subtyper) that integrates tissue-specific eQTLs with GWAS data for a complex trait to probabilistically assign a tissue of interest to the phenotype of each individual in the study. eGST estimates the posterior probability that an individual's phenotype can be assigned to a tissue based on individual-level genotype data of tissue-specific eQTLs and marginal phenotype data in a genome-wide association study (GWAS) cohort. Under a Bayesian framework of mixture model, eGST employs a maximum a posteriori (MAP) expectation-maximization (EM) algorithm to estimate the tissue-specific posterior probability across individuals. Methodology is available from: A Majumdar, C Giambartolomei, N Cai, MK Freund, T Haldar, T Schwarz, J Flint, B Pasaniuc (2019) <doi:10.1101/674226>.

Testing for and dating periods of explosive dynamics (exuberance) in time series using the univariate and panel recursive unit root tests proposed by Phillips et al. (2015) <doi:10.1111/iere.12132> and Pavlidis et al. (2016) <doi:10.1007/s11146-015-9531-2>.The recursive least-squares algorithm utilizes the matrix inversion lemma to avoid matrix inversion which results in significant speed improvements. Simulation of a variety of periodically-collapsing bubble processes. Details can be found in Vasilopoulos et al. (2022) <doi:10.18637/jss.v103.i10>.

This package contains a collection of examples of evidence factors in observational studies from the book Replication and Evidence Factors in Observational Studies by Paul R. Rosenbaum (2021) <doi:10.1201/9781003039648>.

Tests the equality of two covariance matrices, used in paper "Two sample tests for high dimensional covariance matrices." Li and Chen (2012) <arXiv:1206.0917>.

Calculates 15 different goodness of fit criteria. These are; standard deviation ratio (SDR), coefficient of variation (CV), relative root mean square error (RRMSE), Pearson's correlation coefficients (PC), root mean square error (RMSE), performance index (PI), mean error (ME), global relative approximation error (RAE), mean relative approximation error (MRAE), mean absolute percentage error (MAPE), mean absolute deviation (MAD), coefficient of determination (R-squared), adjusted coefficient of determination (adjusted R-squared), Akaike's information criterion (AIC), corrected Akaike's information criterion (CAIC), Mean Square Error (MSE), Bayesian Information Criterion (BIC) and Normalized Mean Square Error (NMSE).

This package provides a robust and efficient solution for working with Ethiopian dates. It can seamlessly convert to and from Gregorian dates. It is designed to be compatible with the tidyverse data workflow, including plotting with ggplot2'. It ensures lightning-fast computations by integrating high-performance C++ code through Rcpp package.

This package provides an interface to the European Central Bank's Data Portal API, allowing for programmatic retrieval of a vast quantity of statistical data.

An implementation of European Forestry Dynamics Model (EFDM) and an estimation algorithm for the transition probabilities. The EFDM is a large-scale forest model that simulates the development of the forest and estimates volume of wood harvested for any given forested area. This estimate can be broken down by, for example, species, site quality, management regime and ownership category. See Packalen et al. (2015) <doi:10.2788/153990>.

This package provides functions for the echelon analysis proposed by Myers et al. (1997) <doi:10.1023/A:1018518327329>, and the detection of spatial clusters using echelon scan method proposed by Kurihara (2003) <doi:10.20551/jscswabun.15.2_171>.

This package provides a collection of tools for representing epidemiological contact data, composed of case line lists and contacts between cases. Also contains procedures for data handling, interactive graphics, and statistics.

Forecasting univariate time series with different decomposition based Extreme Learning Machine models. For method details see Yu L, Wang S, Lai KK (2008). <doi:10.1016/j.eneco.2008.05.003>, Parida M, Behera MK, Nayak N (2018). <doi:10.1109/ICSESP.2018.8376723>.

Uses data and constants to calculate potential evapotranspiration (PET) and actual evapotranspiration (AET) from 21 different formulations including Penman, Penman-Monteith FAO 56, Priestley-Taylor and Morton formulations.

This package provides a set of functions to solve Erlang-C model. The Erlang C formula was invented by the Danish Mathematician A.K. Erlang and is used to calculate the number of advisors and the service level.

Estimation of production functions by the Olley-Pakes, Levinsohn-Petrin and Wooldridge methodologies. The package aims to reproduce the results obtained with the Stata's user written opreg <http://www.stata-journal.com/article.html?article=st0145> and levpet <http://www.stata-journal.com/article.html?article=st0060> commands. The first was originally proposed by Olley, G.S. and Pakes, A. (1996) <doi:10.2307/2171831>. The second by Levinsohn, J. and Petrin, A. (2003) <doi:10.1111/1467-937X.00246>. And the third by Wooldridge (2009) <doi:10.1016/j.econlet.2009.04.026>.

This new extreme conformal prediction framework provides informative prediction intervals at the high-confidence levels for which classical conformal methods fail. In applications with potentially high-impact events, a very high level of confidence is often required for predictions. If that level is too large relative to the amount of data used for calibration, classical conformal methods provide infinitely wide, thus, uninformative prediction intervals. Our extreme conformal procedure bridges extreme value statistics and conformal prediction to provide reliable and informative prediction intervals with high-confidence coverage, which can be constructed using any black-box extreme quantile regression method. A weighted version of the approach can account for nonstationary data. The methodology was introduced in Pasche, Lam, and Engelke (2026) <doi:10.1007/s10687-026-00536-9>.

This package implements choice models based on economic theory, including estimation using Markov chain Monte Carlo (MCMC), prediction, and more. Its usability is inspired by ideas from tidyverse'. Models include versions of the Hierarchical Multinomial Logit and Multiple Discrete-Continous (Volumetric) models with and without screening. The foundations of these models are described in Allenby, Hardt and Rossi (2019) <doi:10.1016/bs.hem.2019.04.002>. Models with conjunctive screening are described in Kim, Hardt, Kim and Allenby (2022) <doi:10.1016/j.ijresmar.2022.04.001>. Models with set-size variation are described in Hardt and Kurz (2020) <doi:10.2139/ssrn.3418383>.

Process and analyze electronic health record (EHR) data. The EHR package provides modules to perform diverse medication-related studies using data from EHR databases. Especially, the package includes modules to perform pharmacokinetic/pharmacodynamic (PK/PD) analyses using EHRs, as outlined in Choi, Beck, McNeer, Weeks, Williams, James, Niu, Abou-Khalil, Birdwell, Roden, Stein, Bejan, Denny, and Van Driest (2020) <doi:10.1002/cpt.1787>. Additional modules will be added in future. In addition, this package provides various functions useful to perform Phenome Wide Association Study (PheWAS) to explore associations between drug exposure and phenotypes obtained from EHR data, as outlined in Choi, Carroll, Beck, Mosley, Roden, Denny, and Van Driest (2018) <doi:10.1093/bioinformatics/bty306>.

This package contains a set of clustering methods and evaluation metrics to select the best number of the clusters based on clustering stability. Two references describe the methodology: Fahimeh Nezhadmoghadam, and Jose Tamez-Pena (2021)<doi:10.1016/j.compbiomed.2021.104753>, and Fahimeh Nezhadmoghadam, et al.(2021)<doi:10.2174/1567205018666210831145825>.

This package provides methods for data analysis from an entropic perspective. These methods are nonparametric and perform well on non-ordinal data. Currently includes HeatMap() for visualizing distributional characteristics among multiple populations (groups).

This package provides a set of methods to access and parse live filing information from the U.S. Securities and Exchange Commission (SEC - <https://www.sec.gov/>) including company and fund filings along with all associated metadata.

Computes the Road Tolerance Index (RTI) and the Human Footprint Tolerance Index (HFTI) for species occurrence data. It automates data cleaning and integrates spatial data (roads and human footprint) to produce reproducible tolerance metrics for biodiversity and conservation research. The HFTI calculation is based on the global human footprint dataset by Mu et al. (2022) <doi:10.1038/s41597-022-01284-8>. This package is part of a PhD thesis focused on amphibian ecology in Brazil.

Expectile regression is a nice tool for estimating the conditional expectiles of a response variable given a set of covariates. This package implements a regression tree based gradient boosting estimator for nonparametric multiple expectile regression, proposed by Yang, Y., Qian, W. and Zou, H. (2018) <doi:10.1080/00949655.2013.876024>. The code is based on the gbm package originally developed by Greg Ridgeway.

This package performs a compact genetic algorithm search to reduce errors-in-variables bias in linear regression. The algorithm estimates the regression parameters with lower biases and higher variances but mean-square errors (MSEs) are reduced.