This package implements the algorithm described in Barron, M., and Li, J. (Not yet published). This algorithm clusters samples from multiple ordered populations, links the clusters across the conditions and identifies marker genes for these changes. The package was designed for scRNA-Seq data but is also applicable to many other data types, just replace cells with samples and genes with variables. The package also contains functions for estimating the parameters for SparseMDC as outlined in the paper. We recommend that users further select their marker genes using the magnitude of the cluster centers.

Extends the functionality of R serialization by augmenting the built-in reference hook system. This enhanced implementation allows optimal, one-pass integrated serialization that combines R serialization with third-party serialization methods. Facilitates the serialization of even complex R objects, which contain non-system reference objects, such as those accessed via external pointers, for use in parallel and distributed computing.

This package implements the Staggered Synthetic Control (SSC) method for estimating treatment effects in panel data with staggered adoption, as proposed by Cao, Lu, and Wu (2020) <doi:10.48550/arXiv.1912.06320>. Constructs synthetic control weights via constrained quadratic programming, estimates heterogeneous treatment effects and event-time average treatment effects on the treated (ATT), and provides placebo-in-time confidence intervals and p-values.

Efficient regression analysis under general two-phase sampling, where Phase I includes error-prone data and Phase II contains validated data on a subset.

Validate data.frames against schemas to ensure that data matches expectations. Define schemas using tidyselect and predicate functions for type consistency, nullability, and more. Schema failure messages can be tailored for non-technical users and are ideal for user-facing applications such as in shiny or plumber'.

Phenotypic analysis of data coming from high throughput phenotyping (HTP) platforms, including different types of outlier detection, spatial analysis, and parameter estimation. The package is being developed within the EPPN2020 project (<https://cordis.europa.eu/project/id/731013>). Some functions have been created to be used in conjunction with the R package asreml for the ASReml software, which can be obtained upon purchase from VSN international (<https://vsni.co.uk/software/asreml-r/>).

Based on the illness-death model a large number of clinical trials with oncology endpoints progression-free survival (PFS) and overall survival (OS) can be simulated, see Meller, Beyersmann and Rufibach (2019) <doi:10.1002/sim.8295>. The simulation set-up allows for random and event-driven censoring, an arbitrary number of treatment arms, staggered study entry and drop-out. Exponentially, Weibull and piecewise exponentially distributed survival times can be generated. The correlation between PFS and OS can be calculated.

An implementation of ranked sparsity methods, including penalized regression methods such as the sparsity-ranked lasso, its non-convex alternatives, and elastic net, as well as the sparsity-ranked Bayesian Information Criterion. As described in Peterson and Cavanaugh (2022) <doi:10.1007/s10182-021-00431-7>, ranked sparsity is a philosophy with methods primarily useful for variable selection in the presence of prior informational asymmetry, which occurs in the context of trying to perform variable selection in the presence of interactions and/or polynomials. Ultimately, this package attempts to facilitate dealing with cumbersome interactions and polynomials while not avoiding them entirely. Typically, models selected under ranked sparsity principles will also be more transparent, having fewer falsely selected interactions and polynomials than other methods.

Simulation methods to study the effect of management policies on efforts to restore populations back to their original genetic composition. Allows for single-scenario simulation and for optimization of specific chosen scenarios. Further information can be found in Hernandez, Janzen and Lavretsky (2023) <doi:10.1111/1755-0998.13892>.

An analytic framework for the calculation of norm- and criterion-referenced academic growth estimates using large scale, longitudinal education assessment data as developed in Betebenner (2009) <doi:10.1111/j.1745-3992.2009.00161.x>.

This package implements the S-type estimators, novel robust estimators for general linear regression models, addressing challenges such as outlier contamination and leverage points. This package introduces robust regression techniques to provide a robust alternative to classical methods and includes diagnostic tools for assessing model fit and performance. The methodology is based on the study, "Comparison of the Robust Methods in the General Linear Regression Model" by Sazak and Mutlu (2023). This package is designed for statisticians and applied researchers seeking advanced tools for robust regression analysis.

This package provides a reusable shiny module for viewing tabular data with a searchable reactable table and a variable summary sidebar built with bslib'.

An interface to access data from Substack publications via API. Users can fetch the latest, top, search for specific posts, or retrieve a single post by its slug. This functionality is useful for developers and researchers looking to analyze Substack content or integrate it into their applications. For more information, visit the API documentation at <https://substackapi.dev/introduction>.

Data sets and code blocks for the book Statistical Analysis of Network Data with R, 2nd Edition'.

This package provides a set of tools for writing and sharing interactive courses to be used with swirl.

This package provides a simple authentification mechanism for single shiny applications. Authentification and password change functionality are performed calling user provided functions that typically access some database backend. Source code of main applications is protected until authentication is successful.

This package implements two iterative techniques called T3Clus and 3Fkmeans, aimed at simultaneously clustering objects and a factorial dimensionality reduction of variables and occasions on three-mode datasets developed by Vichi et al. (2007) <doi:10.1007/s00357-007-0006-x>. Also, we provide a convex combination of these two simultaneous procedures called CT3Clus and based on a hyperparameter alpha (alpha in [0,1], with 3FKMeans for alpha=0 and T3Clus for alpha= 1) also developed by Vichi et al. (2007) <doi:10.1007/s00357-007-0006-x>. Furthermore, we implemented the traditional tandem procedures of T3Clus (TWCFTA) and 3FKMeans (TWFCTA) for sequential clustering-factorial decomposition (TWCFTA), and vice-versa (TWFCTA) proposed by P. Arabie and L. Hubert (1996) <doi:10.1007/978-3-642-79999-0_1>.

Implement different Item Response Theory (IRT) based procedures for the development of tests from item bank. The procedures are flexible enough to be adopted for the development of short forms of full-length tests. Different procedures are considered (Epifania, Anselmi & Robusto, 2022 <doi:10.1007/978-3-031-27781-8_7> and Epifania & Finos, 2025 <doi:10.1007/978-3-031-95995-0_32>). The main difference between the presented procedures refers to the degree of control that they allow for targeting specific latent trait levels. The simplest procedure, denoted as benchmark procedure, does not allow for any control on the latent trait levels of interest, while the other procedures allow for specifying either discrete latent trait levels for which the information needs to be maximized (theta-target procedure, <doi:10.1007/978-3-031-27781-8_7>) or a target information function that needs to be recreated with the selected items (item selection algorithm -ISA- denoted as Frank in <doi:10.1007/978-3-031-95995-0_32>). Another difference concerns the definition of the number of items to be selected. In the benchmark and theta-target procedures, the number of items must be defined a priori, while in ISA the number of items is determined automatically by the algorithm.

Fitting of non-parametric production frontiers for use in efficiency analysis. Methods are provided for both a smooth analogue of Data Envelopment Analysis (DEA) and a non-parametric analogue of Stochastic Frontier Analysis (SFA). Frontiers are constructed for multiple inputs and a single output using constrained kernel smoothing as in Racine et al. (2009), which allow for the imposition of monotonicity and concavity constraints on the estimated frontier.

Obtains lists of files of remote sensing collections for Southern Ocean surface properties. Commonly used data sources of sea surface temperature, sea ice concentration, and altimetry products such as sea surface height and sea surface currents are cached in object storage on the Pawsey Supercomputing Research Centre facility. Patterns of working to retrieve data from these object storage catalogues are described. The catalogues include complete collections of datasets Reynolds et al. (2008) "NOAA Optimum Interpolation Sea Surface Temperature (OISST) Analysis, Version 2.1" <doi:10.7289/V5SQ8XB5>, Spreen et al. (2008) "Artist Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E) sea ice concentration" <doi:10.1029/2005JC003384>. In future releases helpers will be added to identify particular data collections and target specific dates for earth observation data for reading, as well as helpers to retrieve data set citation and provenance details. This work was supported by resources provided by the Pawsey Supercomputing Research Centre with funding from the Australian Government and the Government of Western Australia. This software was developed by the Integrated Digital East Antarctica program of the Australian Antarctic Division.

The main function is icweib(), which fits a stratified Weibull proportional hazards model for left censored, right censored, interval censored, and non-censored survival data. We parameterize the Weibull regression model so that it allows a stratum-specific baseline hazard function, but where the effects of other covariates are assumed to be constant across strata. Please refer to Xiangdong Gu, David Shapiro, Michael D. Hughes and Raji Balasubramanian (2014) <doi:10.32614/RJ-2014-003> for more details.

This package provides tools for setting up ("design"), conducting, and evaluating large-scale simulation studies with graphics and tables, including parallel computations.

Explains the behavior of a time series by decomposing it into its trend, seasonality and residuals. It is built to perform very well in the presence of significant level shifts. It is designed to play well with any breakpoint algorithm and any smoothing algorithm. Currently defaults to lowess for smoothing and strucchange for breakpoint identification. The package is useful in areas such as trend analysis, time series decomposition, breakpoint identification and anomaly detection.

This package implements a semi-supervised learning framework for finite mixture models under a mixed-missingness mechanism. The approach models both missing completely at random (MCAR) and entropy-based missing at random (MAR) processes using a logisticâ entropy formulation. Estimation is carried out via an Expectationâ -Conditional Maximisation (ECM) algorithm with robust initialisation routines for stable convergence. The methodology relates to the statistical perspective and informative missingness behaviour discussed in Ahfock and McLachlan (2020) <doi:10.1007/s11222-020-09971-5> and Ahfock and McLachlan (2023) <doi:10.1016/j.ecosta.2022.03.007>. The package provides functions for data simulation, model estimation, prediction, and theoretical Bayes error evaluation for analysing partially labelled data under a mixed-missingness mechanism.