This package provides tools for processing and evaluating seasonal weather forecasts, with an emphasis on tercile forecasts. We follow the World Meteorological Organization's "Guidance on Verification of Operational Seasonal Climate Forecasts", S.J.Mason (2018, ISBN: 978-92-63-11220-0, URL: <https://library.wmo.int/idurl/4/56227>). The development was supported by the European Unionâ s Horizon 2020 research and innovation programme under grant agreement no. 869730 (CONFER). A comprehensive online tutorial is available at <https://seasonalforecastingengine.github.io/SeaValDoc/>.

Estimation of robust estimators for multi-group and spatial data including the casewise robust Spatially Smoothed Minimum Regularized Determinant (ssMRCD) estimator and its usage for local outlier detection as described in Puchhammer and Filzmoser (2023) <doi:10.1080/10618600.2023.2277875> as well as for sparse robust PCA for multi-source data described in Puchhammer, Wilms and Filzmoser (2024) <doi:10.48550/arXiv.2407.16299>. Moreover, a cellwise robust multi-group Gaussian mixture model (MG-GMM) is implemented as described in Puchhammer, Wilms and Filzmoser (2024) <doi:10.48550/arXiv.2504.02547>. Included are also complementary visualization and parameter tuning tools.

Sequences sampled at different time points can be used to infer molecular phylogenies on natural time scales, but if the sequences records inaccurate sampling times, that are not the actual sampling times, then it will affect the molecular phylogenetic analysis. This shiny application helps exploring temporal characteristics of the evolutionary trees through linear regression analysis and with the ability to identify and remove incorrect labels. The method was extended to support exploring other phylogenetic signals under strict and relaxed models.

Generally, soil functionality is characterized by its capability to sustain microbial activity, nutritional element supply, structural stability and aid for crop production. Since soil functions can be linked to 80% of ecosystem services, conservation of degraded land should strive to restore not only the capacity of soil to sustain flora but also ecosystem provisions. The primary ecosystem services of soil are carbon sequestration, food or biomass production, provision of microbial habitat, nutrient recycling. However, the actual magnitude of soil functions provided by agricultural land uses has never been quantified. Nutrient supply capacity (NSC) is a measure of nutrient dynamics in restored land uses. Carbon accumulation proficiency (CAP) is a measure of ecosystem carbon sequestration. Biological activity index (BAI) is the average of responses of all enzyme activities in treated land over control/reference land. The CAP parameter investigates how land uses may affect carbon flows, retention, and sequestration. The CAP provides a signal for C cycles, flows, and the systems relative operational supremacy.

Implementation of the structural model for variances in order to detect differentially expressed genes from gene expression data.

This package provides a collection of functions that enable easy access and updating of a database of data over time. More specifically, the package facilitates type-2 history for data-warehouses and provides a number of Quality of life improvements for working on SQL databases with R. For reference see Ralph Kimball and Margy Ross (2013, ISBN 9781118530801).

Estimate the parameters of multivariate endogenous switching and sample selection models using methods described in Newey (2009) <doi:10.1111/j.1368-423X.2008.00263.x>, E. Kossova, B. Potanin (2018) <https://ideas.repec.org/a/ris/apltrx/0346.html>, E. Kossova, L. Kupriianova, B. Potanin (2020) <https://ideas.repec.org/a/ris/apltrx/0391.html> and E. Kossova, B. Potanin (2022) <https://ideas.repec.org/a/ris/apltrx/0455.html>.

Inspired by space-time regressions often performed to assess the expansion of the Neolithic from the Near East to Europe (Pinhasi et al. 2005 <doi:10.1371/journal.pbio.0030410>). Test for significant correlations between the (earliest) radiocarbon dates of archaeological sites and their respective distances from a hypothetical center of origin. Both ordinary least squares (OLS) and reduced major axis (RMA) methods are supported (Russell et al. 2014 <doi:10.1371/journal.pone.0087854>). It is also possible to iterate over many sites to identify the most likely origin.

This package provides functionality to fit and simulate from stationary vine copula models for time series, see Nagler et al. (2022) <doi:10.1016/j.jeconom.2021.11.015>.

This package provides estimates for the bivariate and trivariate distribution functions and bivariate and trivariate survival functions for censored gap times. Two approaches, using existing methodologies, are considered: (i) the Lin's estimator, which is based on the extension the Kaplan-Meier estimator of the distribution function for the first event time and the Inverse Probability of Censoring Weights for the second time (Lin DY, Sun W, Ying Z (1999) <doi:10.1093/biomet/86.1.59> and (ii) another estimator based on Kaplan-Meier weights (Una-Alvarez J, Meira-Machado L (2008) <https://w3.math.uminho.pt/~lmachado/Biometria_conference.pdf>). The proposed methods are the landmark estimators based on subsampling approach, and the estimator based on weighted cumulative hazard estimator. The package also provides nonparametric estimator conditional to a given continuous covariate. All these methods have been submitted to be published.

Collection of functions to connect the structure of the data with the information on the samples. Three types of associations are covered: 1. linear model of principal components. 2. hierarchical clustering analysis. 3. distribution of features-sample annotation associations. Additionally, the inter-relation between sample annotations can be analyzed. Simple methods are provided for the correction of batch effects and removal of principal components.

Universal and robust algorithm for solving the total alkalinity-pH equation presented in G. Munhoven (2013) <doi:10.5194/gmd-6-1367-2013> and G. Munhoven (2021) <doi:10.5194/gmd-2020-447>. The total alkalinity-pH equation relates total alkalinity and pH for a given set of acid-base concentrations in a given water sample, among which carbonic acid. This package is particularly useful in marine chemistry involving dissolved inorganic carbon. Original package in Fortran can be found at <doi:10.5281/zenodo.4328965>.

Quantifies clustering quality by measuring both cohesion within clusters and separation between clusters. Implements advanced silhouette width computations for diverse clustering structures, including: simplified silhouette (Van der Laan et al., 2003) <doi:10.1080/0094965031000136012>, Probability of Alternative Cluster normalization methods (Raymaekers & Rousseeuw, 2022) <doi:10.1080/10618600.2022.2050249>, fuzzy clustering and silhouette diagnostics using membership probabilities (Campello & Hruschka, 2006; Menardi, 2011; Bhat & Kiruthika, 2024) <doi:10.1016/j.fss.2006.07.006>, <doi:10.1007/s11222-010-9169-0>, <doi:10.1080/23737484.2024.2408534>, and multi-way clustering extensions such as block and tensor clustering (Schepers et al., 2008; Bhat & Kiruthika, 2025) <doi:10.1007/s00357-008-9005-9>, <doi:10.21203/rs.3.rs-6973596/v1>. Provides tools for computation and visualization (Rousseeuw, 1987) <doi:10.1016/0377-0427(87)90125-7> to support robust and reproducible cluster diagnostics across standard, soft, and multi-way clustering settings.

This package performs cluster analysis of mixed-type data using Spectral Clustering, see F. Mbuga and, C. Tortora (2022) <doi:10.3390/stats5010001>.

This package provides a computational framework for identification of B cell clones from Adaptive Immune Receptor Repertoire sequencing (AIRR-Seq) data. Three main functions are included (identicalClones, hierarchicalClones, and spectralClones) that perform clustering among sequences of BCRs/IGs (B cell receptors/immunoglobulins) which share the same V gene, J gene and junction length. Nouri N and Kleinstein SH (2018) <doi: 10.1093/bioinformatics/bty235>. Nouri N and Kleinstein SH (2019) <doi: 10.1101/788620>. Gupta NT, et al. (2017) <doi: 10.4049/jimmunol.1601850>.

This package provides tools for smoothing and tidying spatial features (i.e. lines and polygons) to make them more aesthetically pleasing. Smooth curves, fill holes, and remove small fragments from lines and polygons.

Supports eigenvalue block-averaging p-values (Foldnes, Grønneberg, 2018) <doi:10.1080/10705511.2017.1373021>, penalized eigenvalue block-averaging p-values (Foldnes, Moss, Grønneberg, 2024) <doi:10.1080/10705511.2024.2372028>, penalized regression p-values (Foldnes, Moss, Grønneberg, 2024) <doi:10.1080/10705511.2024.2372028>, as well as traditional p-values such as Satorra-Bentler. All p-values can be calculated using unbiased or biased gamma estimates (Du, Bentler, 2022) <doi:10.1080/10705511.2022.2063870> and two choices of chi square statistics.

Estimate morphometric and gonadal size at sexual maturity for organisms, usually fish and invertebrates. It includes methods for classification based on relative growth (using principal components analysis, hierarchical clustering, discriminant analysis), logistic regression (Frequentist or Bayes), parameters estimation and some basic plots.

Single cell resolution data has been valuable in learning about tissue microenvironments and interactions between cells or spots. This package allows for the simulation of this level of data, be it single cell or â spotsâ , in both a univariate (single metric or cell type) and bivariate (2 or more metrics or cell types) ways. As more technologies come to marker, more methods will be developed to derive spatial metrics from the data which will require a way to benchmark methods against each other. Additionally, as the field currently stands, there is not a gold standard method to be compared against. We set out to develop an R package that will allow users to simulate point patterns that can be biologically informed from different tissue domains, holes, and varying degrees of clustering/colocalization. The data can be exported as spatial files and a summary file (like HALO'). <https://github.com/FridleyLab/scSpatialSIM/>.

This package implements a sequential imputation framework using Bayesian Mixed-Effects Trees ('SBMTrees') for handling missing data in longitudinal studies. The package supports a variety of models, including non-linear relationships and non-normal random effects and residuals, leveraging Dirichlet Process priors for increased flexibility. Key features include handling Missing at Random (MAR) longitudinal data, imputation of both covariates and outcomes, and generating posterior predictive samples for further analysis. The methodology is designed for applications in epidemiology, biostatistics, and other fields requiring robust handling of missing data in longitudinal settings.

An ADMM implementation of SDP-1, a semidefinite programming relaxation of the maximum likelihood estimator for fitting a block model. SDP-1 has a tendency to produce equal-sized blocks and is ideal for producing a form of network histogram approximating a nonparametric graphon model. Alternatively, it can be used for community detection. (This is experimental code, proceed with caution.).

Support for reading/writing simple feature ('sf') spatial objects from/to Parquet files. Parquet files are an open-source, column-oriented data storage format from Apache (<https://parquet.apache.org/>), now popular across programming languages. This implementation converts simple feature list geometries into well-known binary format for use by arrow', and coordinate reference system information is maintained in a standard metadata format.

This package provides a set of functions to create SQL tables of gene and SNP information and compose them into a SNP Set, for example to export to a PLINK set.

Procedure to optimally split a dataset for training and testing. SPlit is based on the method of support points, which is independent of modeling methods. Please see Joseph and Vakayil (2021) <doi:10.1080/00401706.2021.1921037> for details. This work is supported by U.S. National Science Foundation grant DMREF-1921873.