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Generalized Odds Rate Mixture Cure (GORMC) model is a flexible model of fitting survival data with a cure fraction, including the Proportional Hazards Mixture Cure (PHMC) model and the Proportional Odds Mixture Cure Model as special cases. This package fit the GORMC model with interval censored data.
Implementation of routines of the author's PhD thesis on gradient-free Gradient Boosting (Werner, Tino (2020) "Gradient-Free Gradient Boosting", URL <https://oops.uni-oldenburg.de/id/eprint/4290>').
Computes probabilities related to group sequential designs for normally distributed test statistics. Enables to derive critical boundaries, power, drift, and confidence intervals of such designs. Supports the alpha spending approach by Lan-DeMets (1994) <doi:10.1002/sim.4780131308>.
This package provides functions to load and analyze three open Electronic Health Records (EHRs) datasets of patients diagnosed with glioblastoma, previously released under the Creative Common Attribution 4.0 International (CC BY 4.0) license. Users can generate basic descriptive statistics, frequency tables and save descriptive summary tables, as well as create and export univariate or bivariate plots. The package is designed to work with the included datasets and to facilitate quick exploratory data analysis and reporting. More information about these three datasets of EHRs of patients with glioblastoma can be found in this article: Gabriel Cerono, Ombretta Melaiu, and Davide Chicco, Clinical feature ranking based on ensemble machine learning reveals top survival factors for glioblastoma multiforme', Journal of Healthcare Informatics Research 8, 1-18 (March 2024). <doi:10.1007/s41666-023-00138-1>.
An interactive document on the topic of goodness of fit analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://predanalyticssessions1.shinyapps.io/ChiSquareGOF/>.
Facilitates the citation of R packages used in analysis projects. Scans project for packages used, gets their citations, and produces a document with citations in the preferred bibliography format, ready to be pasted into reports or manuscripts. Alternatively, grateful can be used directly within an R Markdown or Quarto document.
An implementation of SPRE (standardised predicted random-effects) statistics in R to explore heterogeneity in genetic association meta- analyses, as described by Magosi et al. (2019) <doi:10.1093/bioinformatics/btz590>. SPRE statistics are precision weighted residuals that indicate the direction and extent with which individual study-effects in a meta-analysis deviate from the average genetic effect. Overly influential positive outliers have the potential to inflate average genetic effects in a meta-analysis whilst negative outliers might lower or change the direction of effect. See the getspres website for documentation and examples <https://magosil86.github.io/getspres/>.
Modern Parallel Coordinate Plots have been introduced in the 1980s as a way to visualize arbitrarily many numeric variables. This Grammar of Graphics implementation also incorporates categorical variables into the plots in a principled manner. By separating the data managing part from the visual rendering, we give full access to the users while keeping the number of parameters manageably low.
GitHub apps provide a powerful way to manage fine grained programmatic access to specific git repositories, without having to create dummy users, and which are safer than a personal access token for automated tasks. This package extends the gh package to let you authenticate and interact with GitHub <https://docs.github.com/en/rest/overview> in R as an app.
This package provides a ggplot2 extension that enables visualization of IP (Internet Protocol) addresses and networks. The address space is mapped onto the Cartesian coordinate system using a space-filling curve. Offers full support for both IPv4 and IPv6 (Internet Protocol versions 4 and 6) address spaces.
Gaussian processes are flexible distributions to model functional data. Whilst theoretically appealing, they are computationally cumbersome except for small datasets. This package implements two methods for scaling Gaussian process inference in Stan'. First, a sparse approximation of the likelihood that is generally applicable and, second, an exact method for regularly spaced data modeled by stationary kernels using fast Fourier methods. Utility functions are provided to compile and fit Stan models using the cmdstanr interface. References: Hoffmann and Onnela (2025) <doi:10.18637/jss.v112.i02>.
This is a wrapper for the command line tool googler', which can be found at the following URL: <https://github.com/jarun/googler>.
This package provides methods for fitting macroevolutionary models to phylogenetic trees Pennell (2014) <doi:10.1093/bioinformatics/btu181>.
This package implements cost-benefit analysis primitives from HM Treasury Green Book guidance (HM Treasury, 2022, 2026): the kinked Social Time Preference Rate ('STPR'), discount factors, net present value ('NPV'), equivalent annual cost, and real-terms rebasing using the GDP deflator. Designed for UK central government appraisal and evaluation. Bundled parameter tables carry vintage metadata for reproducibility.
This package provides classes and methods for handling networks or graphs whose nodes are geographical (i.e. locations in the globe). The functionality includes the creation of objects of class geonetwork as a graph with node coordinates, the computation of network measures, the support of spatial operations (projection to different Coordinate Reference Systems, handling of bounding boxes, etc.) and the plotting of the geonetwork object combined with supplementary cartography for spatial representation.
An extension of ggplot2 for creating complex genomic maps. It builds on the power of ggplot2 and tidyverse adding new ggplot2'-style geoms & positions and dplyr'-style verbs to manipulate the underlying data. It implements a layout concept inspired by ggraph and introduces tracks to bring tidiness to the mess that is genomics data.
This package provides a variable selection approach for generalized linear mixed models by L1-penalized estimation is provided, see Groll and Tutz (2014) <doi:10.1007/s11222-012-9359-z>. See also Groll and Tutz (2017) <doi:10.1007/s10985-016-9359-y> for discrete survival models including heterogeneity.
Aligns peak based on peak retention times and matches homologous peaks across samples. The underlying alignment procedure comprises three sequential steps. (1) Full alignment of samples by linear transformation of retention times to maximise similarity among homologous peaks (2) Partial alignment of peaks within a user-defined retention time window to cluster homologous peaks (3) Merging rows that are likely representing homologous substances (i.e. no sample shows peaks in both rows and the rows have similar retention time means). The algorithm is described in detail in Ottensmann et al., 2018 <doi:10.1371/journal.pone.0198311>.
Generalized promotion time cure model (GPTCM) via Bayesian hierarchical modeling for multiscale data integration (Zhao et al. (2025) <doi:10.48550/arXiv.2509.01001>). The Bayesian GPTCMs are applicable for both low- and high-dimensional data.
Efficient algorithms for fitting the regularization path of linear regression, GLM, and Cox regression models with grouped penalties. This includes group selection methods such as group lasso, group MCP, and group SCAD as well as bi-level selection methods such as the group exponential lasso, the composite MCP, and the group bridge. For more information, see Breheny and Huang (2009) <doi:10.4310/sii.2009.v2.n3.a10>, Huang, Breheny, and Ma (2012) <doi:10.1214/12-sts392>, Breheny and Huang (2015) <doi:10.1007/s11222-013-9424-2>, and Breheny (2015) <doi:10.1111/biom.12300>, or visit the package homepage <https://pbreheny.github.io/grpreg/>.
This package provides a framework to assist creation of marine ecosystem models, generating either R or C++ code which can then be optimised using the TMB package and standard R tools. Principally designed to reproduce gadget2 models in TMB', but can be extended beyond gadget2's capabilities. Kasper Kristensen, Anders Nielsen, Casper W. Berg, Hans Skaug, Bradley M. Bell (2016) <doi:10.18637/jss.v070.i05> "TMB: Automatic Differentiation and Laplace Approximation.". Begley, J., & Howell, D. (2004) <https://files01.core.ac.uk/download/pdf/225936648.pdf> "An overview of Gadget, the globally applicable area-disaggregated general ecosystem toolbox. ICES.".
Accurate and computationally efficient p-value calculation methods for a general family of Fisher type statistics (GFisher). The GFisher covers Fisher's combination, Good's statistic, Lancaster's statistic, weighted Z-score combination, etc. It allows a flexible weighting scheme, as well as an omnibus procedure that automatically adapts proper weights and degrees of freedom to a given data. The new p-value calculation methods are based on novel ideas of moment-ratio matching and joint-distribution approximation. The technical details can be found in Hong Zhang and Zheyang Wu (2020) <arXiv:2003.01286>.
Network meta-analyses (mixed treatment comparisons) in the Bayesian framework using JAGS. Includes methods to assess heterogeneity and inconsistency, and a number of standard visualizations. van Valkenhoef et al. (2012) <doi:10.1002/jrsm.1054>; van Valkenhoef et al. (2015) <doi:10.1002/jrsm.1167>.
Reference datasets commonly used in the geosciences. These include standard atomic weights of the elements, a periodic table, a list of minerals including their abbreviations and chemistry, geochemical data of reservoirs (primitive mantle, continental crust, mantle, basalts, etc.), decay constants and isotopic ratios frequently used in geochronology, color codes of the chronostratigraphic chart. In addition, the package provides functions for basic queries of atomic weights, the list of minerals, and chronostratigraphic chart colors. All datasets are fully referenced, and a BibTeX file containing the references is included.