Utility functions for the handling, analysis and visualisation of data from portable emissions measurement systems ('PEMS') and other similar mobile activity monitoring devices. The package includes a dedicated pems data class that manages many of the quality control, unit handling and data archiving issues that can hinder efforts to standardise PEMS research.

This extension of the poems pattern-oriented modeling (POM) framework provides a collection of modules and functions customized for paleontological time-scales, and optimized for single-generation transitions and large populations, across multiple generations.

Conduct a priori power analyses via Monte-Carlo style data simulation for linear and generalized linear mixed-effects models (LMMs/GLMMs). Provides a user-friendly workflow with helper functions to easily define fixed and random effects as well as diagnostic functions to evaluate the adequacy of the results of the power analysis.

This package implements fast, safe, and customizable assertions routines, which can be used in place of base::stopifnot().

This package provides a network-based systems biology tool for flexible identification of phenotype-specific subpathways in the cancer gene expression data with multiple categories (such as multiple subtype or developmental stages of cancer). Subtype Set Enrichment Analysis (SubSEA) and Dynamic Changed Subpathway Analysis (DCSA) are developed to flexible identify subtype specific and dynamic changed subpathways respectively. The operation modes include extraction of subpathways from biological pathways, inference of subpathway activities in the context of gene expression data, identification of subtype specific subpathways with SubSEA, identification of dynamic changed subpathways associated with the cancer developmental stage with DCSA, and visualization of the activities of resulting subpathways by using box plots and heat maps. Its capabilities render the tool could find the specific abnormal subpathways in the cancer dataset with multi-phenotype samples.

Automate pharmacokinetic/pharmacodynamic bioanalytical procedures based on best practices and regulatory recommendations. The package impose regulatory constrains and sanity checking for common bioanalytical procedures. Additionally, PKbioanalysis provides a relational infrastructure for plate management and injection sequence.

Tokenizers break text into pieces that are more usable by machine learning models. Many tokenizers share some preparation steps. This package provides those shared steps, along with a simple tokenizer.

We fit causal models using proxies. We implement two stage proximal least squares estimator. E.J. Tchetgen Tchetgen, A. Ying, Y. Cui, X. Shi, and W. Miao. (2020). An Introduction to Proximal Causal Learning. arXiv e-prints, arXiv-2009 <arXiv:2009.10982>.

It includes functions to download and process the Planet NICFI (Norway's International Climate and Forest Initiative) Satellite Imagery utilizing the Planet Mosaics API <https://developers.planet.com/docs/basemaps/reference/#tag/Basemaps-and-Mosaics>. GDAL (library for raster and vector geospatial data formats) and aria2c (paralleled download utility) must be installed and configured in the user's Operating System.

Bundles the datasets and functions used in the textbook by Philip Pollock and Barry Edwards, an R Companion to Essentials of Political Analysis, Second Edition.

This package provides programmatic access to GitHub API with a focus on project management. Key functionality includes setting up issues and milestones from R objects or YAML configurations, querying outstanding or completed tasks, and generating progress updates in tables, charts, and RMarkdown reports. Useful for those using GitHub in personal, professional, or academic settings with an emphasis on streamlining the workflow of data analysis projects.

This package provides various styles of function chaining methods: Pipe operator, Pipe object, and pipeline function, each representing a distinct pipeline model yet sharing almost a common set of features: A value can be piped to the first unnamed argument of a function and to dot symbol in an enclosed expression. The syntax is designed to make the pipeline more readable and friendly to a wide range of operations.

This package provides a collection of methods for commonly undertaken analytical tasks, primarily developed for Public Health Scotland (PHS) analysts, but the package is also generally useful to others working in the healthcare space, particularly since it has functions for working with Community Health Index (CHI) numbers. The package can help to make data manipulation and analysis more efficient and reproducible.

This package implements Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints and longitudinal efficacy measure from multiple treatment cycles. The package provides flags to fit a variety of model-based phase I design, including 1 stage models with or without individualized dose modification, 3-stage models with or without individualized dose modification, etc. Functions are provided to recommend dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) <doi:10.1002/sim.7134>.

This package provides a Shiny Web Application to predict and visualize concentrations of pharmaceuticals in the aqueous environment. Jagadeesan K., Barden R. and Kasprzyk-Hordern B. (2022) <https://www.ssrn.com/abstract=4306129>.

This package implements permutation tests for any test statistic and randomization scheme and constructs associated confidence intervals as described in Glazer and Stark (2024) <doi:10.48550/arXiv.2405.05238>.

This package provides a toolbox for making R functions and capabilities more accessible to students and professionals from Epidemiology and Public Health related disciplines. Includes a function to report coefficients and confidence intervals from models using robust standard errors (when available), functions that expand ggplot2 plots and functions relevant for introductory papers in Epidemiology or Public Health. Please note that use of the provided data sets is for educational purposes only.

This package provides a suite of functions that fit models that use PPM type priors for partitions. Models include hierarchical Gaussian and probit ordinal models with a (covariate dependent) PPM. If a covariate dependent product partition model is selected, then all the options detailed in Page, G.L.; Quintana, F.A. (2018) <doi:10.1007/s11222-017-9777-z> are available. If covariate values are missing, then the approach detailed in Page, G.L.; Quintana, F.A.; Mueller, P (2020) <doi:10.1080/10618600.2021.1999824> is employed. Also included in the package is a function that fits a Gaussian likelihood spatial product partition model that is detailed in Page, G.L.; Quintana, F.A. (2016) <doi:10.1214/15-BA971>, and multivariate PPM change point models that are detailed in Quinlan, J.J.; Page, G.L.; Castro, L.M. (2023) <doi:10.1214/22-BA1344>. In addition, a function that fits a univariate or bivariate functional data model that employs a PPM or a PPMx to cluster curves based on B-spline coefficients is provided.

This package provides a set of functions to efficiently recognize and clean the continuous dorsal pattern of a female brown anole lizard (Anolis sagrei) traced from ImageJ', an open platform for scientific image analysis (see <https://imagej.net> for more information), and extract common features such as the pattern sinuosity indices, coefficient of variation, and max-min width.

This package implements the methodology of Huling, Smith, and Chen (2020) <doi:10.1080/01621459.2020.1801449>, which allows for subgroup identification for semi-continuous outcomes by estimating individualized treatment rules. It uses a two-part modeling framework to handle semi-continuous data by separately modeling the positive part of the outcome and an indicator of whether each outcome is positive, but still results in a single treatment rule. High dimensional data is handled with a cooperative lasso penalty, which encourages the coefficients in the two models to have the same sign.

Estimate commonly used population genomic statistics and generate publication quality figures. PopGenHelpR uses vcf, geno (012), and csv files to generate output.

This package provides a graphical user interface for viewing and designing various types of graphs of the data. The graphs can be saved in different formats of an image.

This package provides a comprehensive set of tools to simulate, evaluate, and compare model-assisted designs for early-phase (Phase I/II) clinical trials, including: - BOIN12 (Bayesian optimal interval phase 1/11 trial design; Lin et al. (2020) <doi:10.1200/PO.20.00257>), - BOIN-ET (Takeda, K., Taguri, M., & Morita, S. (2018) <doi:10.1002/pst.1864>), - EffTox (Thall, P. F., & Cook, J. D. (2004) <doi:10.1111/j.0006-341X.2004.00218.x>), - Ji3+3 (Joint i3+3 design; Lin, X., & Ji, Y. (2020) <doi:10.1080/10543406.2020.1818250>), - PRINTE (probability intervals of toxicity and efficacy design; Lin, X., & Ji, Y. (2021) <doi:10.1177/0962280220977009>), - STEIN (simple toxicity and efficacy interval design; Lin, R., & Yin, G. (2017) <doi:10.1002/sim.7428>), - TEPI (toxicity and efficacy probability interval design; Li, D. H., Whitmore, J. B., Guo, W., & Ji, Y. (2017) <doi:10.1158/1078-0432.CCR-16-1125>), - uTPI (utility-based toxicity Probability interval design; Shi, H., Lin, R., & Lin, X. (2024) <doi:10.1002/sim.8922>). Includes flexible simulation parameters that allow researchers to efficiently compute operating characteristics under various fixed and random trial scenarios and export the results.

This package provides functions to perform Bayesian inference on absorption time data for Phase-type distributions. The methods of Bladt et al (2003) <doi:10.1080/03461230110106435> and Aslett (2012) <https://www.louisaslett.com/PhD_Thesis.pdf> are provided.