Collection of functions to compute within-study covariances for different effect sizes, data visualization, and single and multiple imputations for missing data. Effect sizes include correlation (r), mean difference (MD), standardized mean difference (SMD), log odds ratio (logOR), log risk ratio (logRR), and risk difference (RD).

The primary aim of MasterBayes is to use Markov chain Monte Carlo (MCMC) techniques to integrate over uncertainty in pedigree configurations estimated from molecular markers and phenotypic data (Hadfield et al. (2006) <doi:10.1111/j.1365-294X.2006.03050.x>). Emphasis is put on the marginal distribution of parameters that relate the phenotypic data to the pedigree. All simulation is done in compiled C++ for efficiency.

This package provides a new method to implement clustering from multiple modality data of certain samples, the function M2SMjF() jointly factorizes multiple similarity matrices into a shared sub-matrix and several modality private sub-matrices, which is further used for clustering. Along with this method, we also provide function to calculate the similarity matrix and function to evaluate the best cluster number from the original data.

Encodes several methods for performing Mendelian randomization analyses with summarized data. Summarized data on genetic associations with the exposure and with the outcome can be obtained from large consortia. These data can be used for obtaining causal estimates using instrumental variable methods.

Implemented are the one-sided and two-sided multiple-direction logrank test for two-sample right censored data. In addition to the statistics p-values are calculated: 1. For the one-sided testing problem one p-value based on a wild bootstrap approach is determined. 2. In the two-sided case one p-value based on a chi-squared approximation and a second p-values based on a permutation approach are calculated. Ditzhaus, M. and Friedrich, S. (2018) <arXiv:1807.05504>. Ditzhaus, M. and Pauly, M. (2018) <arXiv:1808.05627>.

Basic Setup for Projects in R for Monterey County Office of Education. It contains functions often used in the analysis of education data in the county office including seeing if an item is not in a list, rounding in the manner the general public expects, including logos for districts, switching between district names and their county-district-school codes, accessing the local SQL table and making thematically consistent graphs.

Facilitate tasks typically encountered during metabolomics data analysis including data import, filtering, missing value imputation (Stacklies et al. (2007) <doi:10.1093/bioinformatics/btm069>, Stekhoven et al. (2012) <doi:10.1093/bioinformatics/btr597>, Tibshirani et al. (2017) <doi:10.18129/B9.BIOC.IMPUTE>, Troyanskaya et al. (2001) <doi:10.1093/bioinformatics/17.6.520>), normalization (Bolstad et al. (2003) <doi:10.1093/bioinformatics/19.2.185>, Dieterle et al. (2006) <doi:10.1021/ac051632c>, Zhao et al. (2020) <doi:10.1038/s41598-020-72664-6>) transformation, centering and scaling (Van Den Berg et al. (2006) <doi:10.1186/1471-2164-7-142>) as well as statistical tests and plotting. metamorphr introduces a tidy (Wickham et al. (2019) <doi:10.21105/joss.01686>) format for metabolomics data and is designed to make it easier to build elaborate analysis workflows and to integrate them with tidyverse packages including dplyr and ggplot2'.

This package provides a test of multivariate normality of an unknown sample that does not require estimation of the nuisance parameters, the mean and covariance matrix. Rather, a sequence of transformations removes these nuisance parameters and results in a set of sample matrices that are positive definite. These matrices are uniformly distributed on the space of positive definite matrices in the unit hyper-rectangle if and only if the original data is multivariate normal (Fairweather, 1973, Doctoral dissertation, University of Washington). The package performs a goodness of fit test of this hypothesis. In addition to the test, functions in the package give visualizations of the support region of positive definite matrices for bivariate samples.

This package implements Multi-Calibration Boosting (2018) <https://proceedings.mlr.press/v80/hebert-johnson18a.html> and Multi-Accuracy Boosting (2019) <doi:10.48550/arXiv.1805.12317> for the multi-calibration of a machine learning model's prediction. MCBoost updates predictions for sub-groups in an iterative fashion in order to mitigate biases like poor calibration or large accuracy differences across subgroups. Multi-Calibration works best in scenarios where the underlying data & labels are unbiased, but resulting models are. This is often the case, e.g. when an algorithm fits a majority population while ignoring or under-fitting minority populations.

This package implements Multi-Group Sparse Discriminant Analysis proposal of I.Gaynanova, J.Booth and M.Wells (2016), Simultaneous sparse estimation of canonical vectors in the p>>N setting, JASA <doi:10.1080/01621459.2015.1034318>.

Overcomes one of the major challenges in mobile (passive) sensing, namely being able to pre-process the raw data that comes from a mobile sensing app, specifically m-Path Sense <https://m-path.io>. The main task of mpathsenser is therefore to read m-Path Sense JSON files into a database and provide several convenience functions to aid in data processing.

This package provides functions to collapse a tidy data frame into matrices in a data frame and expand a data frame of matrices into a tidy data frame.

Sentiment analysis is a popular technique in text mining that attempts to determine the emotional state of some text. We provide a new implementation of a common method for computing sentiment, whereby words are scored as positive or negative according to a dictionary lookup. Then the sum of those scores is returned for the document. We use the Hu and Liu sentiment dictionary ('Hu and Liu', 2004) <doi:10.1145/1014052.1014073> for determining sentiment. The scoring function is vectorized by document, and scores for multiple documents are computed in parallel via OpenMP'.

This package provides a glycolipid mass spectrometry technology has the potential to accurately identify individual bacterial species from polymicrobial samples. To develop bacterial identification algorithms (e.g. machine learning) using this glycolipid technology, it is necessary to generate a large number of various in-silico polymicrobial mass spectra that are similar to real mass spectra. MGMS2 (Membrane Glycolipid Mass Spectrum Simulator) generates such in-silico mass spectra, considering errors in m/z (mass-to-charge ratio) and variances of intensity values, occasions of missing signature ions, and noise peaks. It estimates summary statistics of monomicrobial mass spectra for each strain or species and simulates polymicrobial glycolipid mass spectra using the summary statistics of monomicrobial mass spectra. References: Ryu, S.Y., Wendt, G.A., Chandler, C.E., Ernst, R.K. and Goodlett, D.R. (2019) <doi:10.1021/acs.analchem.9b03340> "Model-based Spectral Library Approach for Bacterial Identification via Membrane Glycolipids." Gibb, S. and Strimmer, K. (2012) <doi:10.1093/bioinformatics/bts447> "MALDIquant: a versatile R package for the analysis of mass spectrometry data.".

Extends the mlr3 package with a connector to the package batchtools'. This allows to run large-scale benchmark experiments on scheduled high-performance computing clusters.

This package creates a spectroscopy guideline with a highly accurate prediction model for soil properties using machine learning or deep learning algorithms such as LASSO, Random Forest, Cubist, etc., and decide which algorithm generates the best model for different soil types.

Implementation of Multiple Comparison Procedures with Modeling (MCP-Mod) procedure with bias-corrected estimators and second-order covariance matrices as described in Diniz, Gallardo and Magalhaes (2023) <doi:10.1002/pst.2303>.

Interactions between different biological entities are crucial for the function of biological systems. In such networks, nodes represent biological elements, such as genes, proteins and microbes, and their interactions can be defined by edges, which can be either binary or weighted. The dysregulation of these networks can be associated with different clinical conditions such as diseases and response to treatments. However, such variations often occur locally and do not concern the whole network. To capture local variations of such networks, we propose multiplex network differential analysis (MNDA). MNDA allows to quantify the variations in the local neighborhood of each node (e.g. gene) between the two given clinical states, and to test for statistical significance of such variation. Yousefi et al. (2023) <doi:10.1101/2023.01.22.525058>.

Data sets from a variety of biological sample matrices, analysed using a number of mass spectrometry based metabolomic analytical techniques. The example data sets are stored remotely using GitHub releases <https://github.com/aberHRML/metaboData/releases> which can be accessed from R using the package. The package also includes the abr1 FIE-MS data set from the FIEmspro package <https://users.aber.ac.uk/jhd/> <doi:10.1038/nprot.2007.511>.

An RStudio Addin wrapper for the mergen package. This package employs artificial intelligence to convert data analysis questions into executable code, explanations, and algorithms. This package makes it easier to use Large Language Models in your development environment by providing a chat-like interface, while also allowing you to inspect and execute the returned code.

This package provides tools to perform interrupted-time series through a generalised least squares (GLS) framework on linear outcomes. Allows for multiple interventions and a control with ARMA (autoregressive and moving-average) correction. For more details see Lopez Bernal, Cummins, and Gasparrini (2017) <doi:10.1093/ije/dyw098>.

This package provides tools for systematic comparison of data frames, offering functionality to identify, quantify, and extract differences. Provides functions with user-friendly and interactive console output for immediate analysis, while also offering options to export differences as structured data frames that can be easily integrated into existing workflows.

Generic functions to produce area/bar/box/line plots of data following IAMC (Integrated Assessment Modeling Consortium) submission format.

This package offers three important components: (1) to construct a use-defined linear mixed model, (2) to employ one of linear mixed model approaches: minimum norm quadratic unbiased estimation (MINQUE) (Rao, 1971) for variance component estimation and random effect prediction; and (3) to employ a jackknife resampling technique to conduct various statistical tests. In addition, this package provides the function for model or data evaluations.This R package offers fast computations for large data sets analyses for various irregular data structures.