This package provides functions to install SciViews additions to R, and more tools.

In a clinical trial with repeated measures designs, outcomes are often taken from subjects at fixed time-points. The focus of the trial may be to compare the mean outcome in two or more groups at some pre-specified time after enrollment. In the presence of missing data auxiliary assumptions are necessary to perform such comparisons. One commonly employed assumption is the missing at random assumption (MAR). The samon package allows the user to perform a (parameterized) sensitivity analysis of this assumption. In particular it can be used to examine the sensitivity of tests in the difference in outcomes to violations of the MAR assumption. The sensitivity analysis can be performed under two scenarios, a) where the data exhibit a monotone missing data pattern (see the samon() function), and, b) where in addition to a monotone missing data pattern the data exhibit intermittent missing values (see the samonIM() function).

Latent space models for multivariate networks (multiplex) estimated via MCMC algorithm. See D Angelo et al. (2018) <arXiv:1803.07166> and D Angelo et al. (2018) <arXiv:1807.03874>.

An updated and extended version of spm package, by introducing some further novel functions for modern statistical methods (i.e., generalised linear models, glmnet, generalised least squares), thin plate splines, support vector machine, kriging methods (i.e., simple kriging, universal kriging, block kriging, kriging with an external drift), and novel hybrid methods (228 hybrids plus numerous variants) of modern statistical methods or machine learning methods with mathematical and/or univariate geostatistical methods for spatial predictive modelling. For each method, two functions are provided, with one function for assessing the predictive errors and accuracy of the method based on cross-validation, and the other for generating spatial predictions. It also contains a couple of functions for data preparation and predictive accuracy assessment.

The single cell mapper (scMappR) R package contains a suite of bioinformatic tools that provide experimentally relevant cell-type specific information to a list of differentially expressed genes (DEG). The function "scMappR_and_pathway_analysis" reranks DEGs to generate cell-type specificity scores called cell-weighted fold-changes. Users input a list of DEGs, normalized counts, and a signature matrix into this function. scMappR then re-weights bulk DEGs by cell-type specific expression from the signature matrix, cell-type proportions from RNA-seq deconvolution and the ratio of cell-type proportions between the two conditions to account for changes in cell-type proportion. With cwFold-changes calculated, scMappR uses two approaches to utilize cwFold-changes to complete cell-type specific pathway analysis. The "process_dgTMatrix_lists" function in the scMappR package contains an automated scRNA-seq processing pipeline where users input scRNA-seq count data, which is made compatible for scMappR and other R packages that analyze scRNA-seq data. We further used this to store hundreds up regularly updating signature matrices. The functions "tissue_by_celltype_enrichment", "tissue_scMappR_internal", and "tissue_scMappR_custom" combine these consistently processed scRNAseq count data with gene-set enrichment tools to allow for cell-type marker enrichment of a generic gene list (e.g. GWAS hits). Reference: Sokolowski,D.J., Faykoo-Martinez,M., Erdman,L., Hou,H., Chan,C., Zhu,H., Holmes,M.M., Goldenberg,A. and Wilson,M.D. (2021) Single-cell mapper (scMappR): using scRNA-seq to infer cell-type specificities of differentially expressed genes. NAR Genomics and Bioinformatics. 3(1). Iqab011. <doi:10.1093/nargab/lqab011>.

This package provides a set of functions to create SQL tables of gene and SNP information and compose them into a SNP Set, for example to export to a PLINK set.

The skew logistic distribution is a quantile-defined generalisation of the logistic distribution (van Staden and King 2015). Provides random numbers, quantiles, probabilities, densities and density quantiles for the distribution. It provides Quantile-Quantile plots and method of L-Moments estimation (including asymptotic standard errors) for the distribution.

Effect modification occurs if a treatment effect is larger or more stable in certain subgroups defined by observed covariates. The submax or subgroup-maximum method of Lee et al. (2018) <doi:10.1111/biom.12884> does an overall test and separate tests in subgroups, correcting for multiple testing using the joint distribution.

An efficient implementation of SCCI using Rcpp'. SCCI is short for the Stochastic Complexity-based Conditional Independence criterium (Marx and Vreeken, 2019). SCCI is an asymptotically unbiased and L2 consistent estimator of (conditional) mutual information for discrete data.

Network sparsification with a variety of novel and known network sparsification techniques. All network sparsification techniques reduce the number of edges, not the number of nodes. Network sparsification is sometimes referred to as network dimensionality reduction. This package is based on the work of Spielman, D., Srivastava, N. (2009)<arXiv:0803.0929>. Koutis I., Levin, A., Peng, R. (2013)<arXiv:1209.5821>. Toivonen, H., Mahler, S., Zhou, F. (2010)<doi:10.1007>. Foti, N., Hughes, J., Rockmore, D. (2011)<doi:10.1371>.

This package implements a group-bridge penalized function-on-scalar regression model proposed by Wang et al. (2023) <doi:10.1111/biom.13684>, to simultaneously estimate functional coefficient and recover the local sparsity.

Density, distribution function, quantile function and random generation for the sum of independent non-identical binomial distribution with parameters \codesize and \codeprob.

This package provides a tool for cutting data into intervals. Allows singleton intervals. Always includes the whole range of data by default. Flexible labelling. Convenience functions for cutting by quantiles etc. Handles dates, times, units and other vectors.

Modifies the progress() function from httr package to let it send output to progressBar() function from shinyWidgets package. It is just a tweak at the original functions from httr package to make it smooth for shiny developers.

This package provides functions for tabulating and summarizing categorical, multiple response, ordinal, and continuous variables in R data frames. Makes it easy to create clear, structured summary tables, so you spend less time wrangling data and more time interpreting it.

Conduct various tests for evaluating implicit biases in word embeddings: Word Embedding Association Test (Caliskan et al., 2017), <doi:10.1126/science.aal4230>, Relative Norm Distance (Garg et al., 2018), <doi:10.1073/pnas.1720347115>, Mean Average Cosine Similarity (Mazini et al., 2019) <arXiv:1904.04047>, SemAxis (An et al., 2018) <arXiv:1806.05521>, Relative Negative Sentiment Bias (Sweeney & Najafian, 2019) <doi:10.18653/v1/P19-1162>, and Embedding Coherence Test (Dev & Phillips, 2019) <arXiv:1901.07656>.

Fit design-based linear and logistic elastic nets with complex survey data considering the sampling design when defining training and test sets using replicate weights. Methods implemented in this package are described in: A. Iparragirre, T. Lumley, I. Barrio, I. Arostegui (2024) <doi:10.1002/sta4.578>.

C++ classes for sparse matrix methods including implementation of sparse LDL decomposition of symmetric matrices and solvers described by Timothy A. Davis (2016) <https://fossies.org/linux/SuiteSparse/LDL/Doc/ldl_userguide.pdf>. Provides a set of C++ classes for basic sparse matrix specification and linear algebra, and a class to implement sparse LDL decomposition and solvers. See <https://github.com/samuel-watson/SparseChol> for details.

Fast and regularized version of GWR for large dataset, detailed in Murakami, Tsutsumida, Yoshida, Nakaya, and Lu (2019) <arXiv:1905.00266>.

This package provides wrappers for scclust', a C library for computationally efficient size-constrained clustering with near-optimal performance. See <https://github.com/fsavje/scclust> for more information.

Simulation tools for planning Vitamin D studies. Individual vitamin D status profiles are simulated, modelling population heterogeneity in trial arms. Exposures to infectious agents are generated, with infection depending on vitamin D status.

This package provides crop yield and meteorological data for Ontario, Canada. Includes functions for fitting and predicting data using spatio-temporal models, as well as tools for visualizing the results. The package builds upon existing R packages, including copula (Hofert et al., 2025) <doi:10.32614/CRAN.package.copula>, and bsts (Scott, 2024) <doi:10.32614/CRAN.package.bsts>.

Univariate stratification of survey populations with a generalization of the Lavallee-Hidiroglou method of stratum construction. The generalized method takes into account a discrepancy between the stratification variable and the survey variable. The determination of the optimal boundaries also incorporate, if desired, an anticipated non-response, a take-all stratum for large units, a take-none stratum for small units, and a certainty stratum to ensure that some specific units are in the sample. The well known cumulative root frequency rule of Dalenius and Hodges and the geometric rule of Gunning and Horgan are also implemented.

This package provides a dynamic model of the big-picture, whole ecosystem effects of hydrodynamics, temperature, nutrients, and fishing on continental shelf marine food webs. The package is described in: Heath, M.R., Speirs, D.C., Thurlbeck, I. and Wilson, R.J. (2020) <doi:10.1111/2041-210X.13510> StrathE2E2: An R package for modelling the dynamics of marine food webs and fisheries. 8pp.