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Estimation of model parameters for marked Hawkes process. Accounts for missing data in the estimation of the parameters. Technical details found in (Tucker et al., 2019 <DOI:10.1016/j.spasta.2018.12.004>).
This package provides functions for sample size estimation and simulation in clinical trials. Includes methods for selecting the best group using the Indifference-zone approach, as well as designs for non-inferiority, equivalence, and negative binomial models. For the sample size calculation for non-inferiority of vaccines, the approach is based on Fleming, Powers, and Huang (2021) <doi:10.1177/1740774520988244>. The Indifference-zone approach is based on Sobel and Huyett (1957) <doi:10.1002/j.1538-7305.1957.tb02411.x> and Bechhofer, Santner, and Goldsman (1995, ISBN:978-0-471-57427-9).
User-friendly functions which parse output of command line programs used to query Slurm. Morris A. Jette and Tim Wickberg (2023) <doi:10.1007/978-3-031-43943-8_1> describe Slurm in detail.
This package provides a computational framework for identification of B cell clones from Adaptive Immune Receptor Repertoire sequencing (AIRR-Seq) data. Three main functions are included (identicalClones, hierarchicalClones, and spectralClones) that perform clustering among sequences of BCRs/IGs (B cell receptors/immunoglobulins) which share the same V gene, J gene and junction length. Nouri N and Kleinstein SH (2018) <doi: 10.1093/bioinformatics/bty235>. Nouri N and Kleinstein SH (2019) <doi: 10.1101/788620>. Gupta NT, et al. (2017) <doi: 10.4049/jimmunol.1601850>.
This package provides tools for calculating disclosure risk measures for microdata, including record-level and file-level measures. The record-level disclosure risk is estimated primarily using exhaustive tabulation. The file-level disclosure risk is estimated by fitting loglinear models on the observed sample counts in cells formed by key variables and their interactions. Funded by the National Center for Education Statistics. See Skinner and Shlomo (2008) <doi:10.1198/016214507000001328> for a description of the file-level risk measures and the loglinear model approach.
Deals with Young tableaux (field of combinatorics). For standard Young tabeaux, performs enumeration, counting, random generation, the Robinson-Schensted correspondence, and conversion to and from paths on the Young lattice. Also performs enumeration and counting of semistandard Young tableaux, enumeration of skew semistandard Young tableaux, enumeration of Gelfand-Tsetlin patterns, and computation of Kostka numbers.
Enables drag-and-drop behaviour in Shiny apps, by exposing the functionality of the SortableJS <https://sortablejs.github.io/Sortable/> JavaScript library as an htmlwidget'. You can use this in Shiny apps and widgets, learnr tutorials as well as R Markdown. In addition, provides a custom learnr question type - question_rank() - that allows ranking questions with drag-and-drop.
This package provides a user-friendly wrapper for web automation, using either chromote or selenium'. Provides a simple and consistent API to make web scraping and testing scripts easy to write and understand. Elements are lazy, and automatically wait for the website to be valid, resulting in reliable and reproducible code, with no visible impact on the experience of the programmer.
An updated and extended version of spm package, by introducing some further novel functions for modern statistical methods (i.e., generalised linear models, glmnet, generalised least squares), thin plate splines, support vector machine, kriging methods (i.e., simple kriging, universal kriging, block kriging, kriging with an external drift), and novel hybrid methods (228 hybrids plus numerous variants) of modern statistical methods or machine learning methods with mathematical and/or univariate geostatistical methods for spatial predictive modelling. For each method, two functions are provided, with one function for assessing the predictive errors and accuracy of the method based on cross-validation, and the other for generating spatial predictions. It also contains a couple of functions for data preparation and predictive accuracy assessment.
Sample size calculation to detect dynamic treatment regime (DTR) effects based on change in clinical attachment level (CAL) outcomes from a non-surgical chronic periodontitis treatments study. The experiment is performed under a Sequential Multiple Assignment Randomized Trial (SMART) design. The clustered tooth (sub-unit) level CAL outcomes are skewed, spatially-referenced, and non-randomly missing. The implemented algorithm is available in Xu et al. (2019+) <arXiv:1902.09386>.
This package provides a major challenge in estimating treatment decision rules from a randomized clinical trial dataset with covariates measured at baseline lies in detecting relatively small treatment effect modification-related variability (i.e., the treatment-by-covariates interaction effects on treatment outcomes) against a relatively large non-treatment-related variability (i.e., the main effects of covariates on treatment outcomes). The class of Single-Index Models with Multiple-Links is a novel single-index model specifically designed to estimate a single-index (a linear combination) of the covariates associated with the treatment effect modification-related variability, while allowing a nonlinear association with the treatment outcomes via flexible link functions. The models provide a flexible regression approach to developing treatment decision rules based on patients data measured at baseline. We refer to Park, Petkova, Tarpey, and Ogden (2020) <doi:10.1016/j.jspi.2019.05.008> and Park, Petkova, Tarpey, and Ogden (2020) <doi:10.1111/biom.13320> (that allows an unspecified X main effect) for detail of the method. The main function of this package is simml().
Read SubRip <https://sourceforge.net/projects/subrip/> subtitle files as data frames for easy text analysis or manipulation. Easily shift numeric timings and export subtitles back into valid SubRip timestamp format to sync subtitles and audio.
This package implements stochastic metafrontier analysis for productivity and performance benchmarking across firms operating under different technologies. Contains routines for the deterministic metafrontier envelope of O'Donnell et al. (2008) <doi:10.1007/s00181-007-0119-4> via linear and quadratic programming, and the stochastic metafrontier of Huang et al. (2014) <doi:10.1007/s11123-014-0402-2>. Also supports latent class stochastic metafrontier analysis and sample selection correction stochastic metafrontier models. Depends on the sfaR package by Dakpo et al. (2023) <https://CRAN.R-project.org/package=sfaR>.
This package provides an implementation of Secretary Bird Optimization for general-purpose continuous optimization, benchmark optimization, and training single-hidden-layer feed-forward neural network models. The implemented optimizer is based on the Secretary Bird Optimization Algorithm proposed by Fu et al. (2024) <doi:10.1007/s10462-024-10729-y>. The neural network training functionality is based on Dilber and à zdemir (2026) <doi:10.1007/s00521-026-11874-x>.
This package provides a modification of the preventive vaccine efficacy trial design of Gilbert, Grove et al. (2011, Statistical Communications in Infectious Diseases) is implemented, with application generally to individual-randomized clinical trials with multiple active treatment groups and a shared control group, and a study endpoint that is a time-to-event endpoint subject to right-censoring. The design accounts for the issues that the efficacy of the treatment/vaccine groups may take time to accrue while the multiple treatment administrations/vaccinations are given; there is interest in assessing the durability of treatment efficacy over time; and group sequential monitoring of each treatment group for potential harm, non-efficacy/efficacy futility, and high efficacy is warranted. The design divides the trial into two stages of time periods, where each treatment is first evaluated for efficacy in the first stage of follow-up, and, if and only if it shows significant treatment efficacy in stage one, it is evaluated for longer-term durability of efficacy in stage two. The package produces plots and tables describing operating characteristics of a specified design including an unconditional power for intention-to-treat and per-protocol/as-treated analyses; trial duration; probabilities of the different possible trial monitoring outcomes (e.g., stopping early for non-efficacy); unconditional power for comparing treatment efficacies; and distributions of numbers of endpoint events occurring after the treatments/vaccinations are given, useful as input parameters for the design of studies of the association of biomarkers with a clinical outcome (surrogate endpoint problem). The code can be used for a single active treatment versus control design and for a single-stage design.
Generates and evaluates D, I, A, Alias, E, T, and G optimal designs. Supports generation and evaluation of blocked and split/split-split/.../N-split plot designs. Includes parametric and Monte Carlo power evaluation functions, and supports calculating power for censored responses. Provides a framework to evaluate power using functions provided in other packages or written by the user. Includes a Shiny graphical user interface that displays the underlying code used to create and evaluate the design to improve ease-of-use and make analyses more reproducible. For details, see Morgan-Wall et al. (2021) <doi:10.18637/jss.v099.i01>.
Validate data.frames against schemas to ensure that data matches expectations. Define schemas using tidyselect and predicate functions for type consistency, nullability, and more. Schema failure messages can be tailored for non-technical users and are ideal for user-facing applications such as in shiny or plumber'.
Given a list of substance compositions, a list of substances involved in a process, and a list of constraints in addition to mass conservation of elementary constituents, the package contains functions to build the substance composition matrix, to analyze the uniqueness of process stoichiometry, and to calculate stoichiometric coefficients if process stoichiometry is unique. (See Reichert, P. and Schuwirth, N., A generic framework for deriving process stoichiometry in enviromental models, Environmental Modelling and Software 25, 1241-1251, 2010 for more details.).
This package provides tools to decompose (transformed) spatial connectivity matrices and perform supervised or unsupervised semiparametric spatial filtering in a regression framework. The package supports unsupervised spatial filtering in standard linear as well as some generalized linear regression models.
Stores the data associated with your amplicon sequence analysis. This includes nucleotide sequences, abundance, sample and treatment assignments, taxonomic classifications, asv, otu and phylotype clusters, metadata, trees and various reports. It is designed to facilitate data analysis across multiple R packages with utility functions to read / write from mothur', qiime2', dada2', and phyloseq'.
This package provides a complete analysis pipeline for the WHO STEPwise Approach to NCD Risk Factor Surveillance (STEPS) as described in Riley et al. (2016) <doi:10.2105/AJPH.2015.302962>. Imports raw survey data ('CSV', Excel', Stata', SPSS'), applies WHO-standard cleaning and recoding, sets up complex survey designs, computes all standard NCD indicators (tobacco, alcohol, diet, physical activity, anthropometry, blood pressure, biochemical), and generates publication-ready tables, visualisations, and Word'/'HTML reports (fact sheet, data book, country report).
Regression inference for multiple populations by integrating summary-level data using stacked imputations. Gu, T., Taylor, J.M.G. and Mukherjee, B. (2021) A synthetic data integration framework to leverage external summary-level information from heterogeneous populations <arXiv:2106.06835>.
This package provides functionality to extract reactive expressions from a shiny application and convert them into stand-alone R scripts. This enables users to reproduce tables and visualisations outside the interactive UI, facilitating integration into static reports or automated workflows without requiring access to the original application source code.
This package provides a lightweight tool that provides a reproducible workflow for selecting and executing appropriate statistical analysis in one-way or two-way experimental designs. The package automatically checks for data normality, conducts parametric (ANOVA) or non-parametric (Kruskal-Wallis) tests, performs post-hoc comparisons with Compact Letter Displays (CLD), and generates publication-ready boxplots, faceted plots, and heatmaps. It is designed for researchers seeking fast, automated statistical summaries and visualization. Based on established statistical methods including Shapiro and Wilk (1965) <doi:10.2307/2333709>, Kruskal and Wallis (1952) <doi:10.1080/01621459.1952.10483441>, Tukey (1949) <doi:10.2307/3001913>, Fisher (1925) <ISBN:0050021702>, and Wickham (2016) <ISBN:978-3-319-24277-4>.