This package implements maximum likelihood methods for evaluating the durability of vaccine efficacy in a randomized, placebo-controlled clinical trial with staggered enrollment of participants and potential crossover of placebo recipients before the end of the trial. Lin, D. Y., Zeng, D., and Gilbert, P. B. (2021) <doi:10.1093/cid/ciab226> and Lin, D. Y., Gu, Y., Zeng, D., Janes, H. E., and Gilbert, P. B. (2021) <doi:10.1093/cid/ciab630>.

This package provides fast, in-memory reading of DATASUS DBC files using native C code, along with a catalog of public health data sources, FTP file discovery, caching downloads, and a high-level datasus_fetch() function that lists, downloads, and reads files in a single call. Bundles the blast decompressor from zlib contrib/blast to decode PKWare DCL compressed DBC files and parses DBF records directly for efficient import into tibbles. See the DATASUS file transfer site <https://datasus.saude.gov.br> and Adler (2003) <https://github.com/madler/zlib/tree/master/contrib/blast> for details on the underlying data and compression format.

This package provides a tidyverse'-friendly interface to DuckLake <https://ducklake.select/>, the DuckDB lakehouse format. Attach versioned data lakes from R and work with them using familiar dplyr verbs, with support for ACID transactions, time travel queries, snapshot audit trails, data inlining, encrypted storage, multiple catalog backends ('DuckDB', PostgreSQL', SQLite', MySQL'), and remote access over the Quack protocol from DuckDB'.

This package contains a single function dclust() for divisive hierarchical clustering based on recursive k-means partitioning (k = 2). Useful for clustering large datasets where computation of a n x n distance matrix is not feasible (e.g. n > 10,000 records). For further information see Steinbach, Karypis and Kumar (2000) <http://glaros.dtc.umn.edu/gkhome/fetch/papers/docclusterKDDTMW00.pdf>.

S4-distribution classes based on package distr for distributions from packages fBasics and fGarch'.

This package provides functions are provided to fit temporal lag models to dynamic networks. The models are build on top of exponential random graph models (ERGM) framework. There are functions for simulating or forecasting networks for future time points. Abhirup Mallik & Zack W. Almquist (2019) Stable Multiple Time Step Simulation/Prediction From Lagged Dynamic Network Regression Models, Journal of Computational and Graphical Statistics, 28:4, 967-979, <DOI: 10.1080/10618600.2019.1594834>.

Abstract of Manuscript. Differential gene expression analysis using RNA sequencing (RNA-seq) data is a standard approach for making biological discoveries. Ongoing large-scale efforts to process and normalize publicly available gene expression data enable rapid and systematic reanalysis. While several powerful tools systematically process RNA-seq data, enabling their reanalysis, few resources systematically recompute differentially expressed genes (DEGs) generated from individual studies. We developed a robust differential expression analysis pipeline to recompute 3162 human DEG lists from The Cancer Genome Atlas, Genotype-Tissue Expression Consortium, and 142 studies within the Sequence Read Archive. After measuring the accuracy of the recomputed DEG lists, we built the Differential Expression Enrichment Tool (DEET), which enables users to interact with the recomputed DEG lists. DEET, available through CRAN and RShiny, systematically queries which of the recomputed DEG lists share similar genes, pathways, and TF targets to their own gene lists. DEET identifies relevant studies based on shared results with the userâ s gene lists, aiding in hypothesis generation and data-driven literature review. Sokolowski, Dustin J., et al. "Differential Expression Enrichment Tool (DEET): an interactive atlas of human differential gene expression." Nucleic Acids Research Genomics and Bioinformatics (2023).

Draws stylized choropleth maps -- hexagonal maps and triangular multiclass hex maps -- for New Zealand District Health Boards and Regional Council areas. These allow faceted, coloured displays of quantitative information for comparison across District Health Boards or Regional Councils. The preprint Lumley (2019) <arXiv:1912.04435> is based on the methods in this package.

Given count data from two conditions, it determines which transcripts are differentially expressed across the two conditions using Bayesian inference of the parameters of a bottom-up model for PCR amplification. This model is developed in Ndifon Wilfred, Hilah Gal, Eric Shifrut, Rina Aharoni, Nissan Yissachar, Nir Waysbort, Shlomit Reich Zeliger, Ruth Arnon, and Nir Friedman (2012), <http://www.pnas.org/content/109/39/15865.full>, and results in a distribution for the counts that is a superposition of the binomial and negative binomial distribution.

Profiles a data frame with minimal input: column type inference, missing-value analysis, distributional summary statistics (including skewness and kurtosis), normality tests, outlier detection, correlation and categorical-association analysis, date-column profiling, grouped comparisons and an overall data-quality score, alongside a set of ggplot2 visualisations. A single entry point, profile_data(), returns a structured S3 object holding metadata, statistics, diagnostics and plots, with print(), summary() and plot() methods, and report() renders the whole profile to a self-contained HTML file. Statistical methods include the Shapiro-Wilk normality test as implemented by Royston (1995) <doi:10.2307/2986146> and the Anderson-Darling test following Stephens (1974) <doi:10.1080/01621459.1974.10480196>, with power comparisons of these tests in Yap and Sim (2011) <doi:10.1080/00949655.2010.520163>, and the categorical association measure of Cramer (1946, ISBN:9780691080048).

This package implements the dynamic panel models described by Allison, Williams, and Moral-Benito (2017 <doi:10.1177/2378023117710578>) in R. This class of models uses structural equation modeling to specify dynamic (lagged dependent variable) models with fixed effects for panel data. Additionally, models may have predictors that are only weakly exogenous, i.e., are affected by prior values of the dependent variable. Options also allow for random effects, dropping the lagged dependent variable, and a number of other specification choices.

Prediction methods where explanatory information is coded as a matrix of distances between individuals. Distances can either be directly input as a distances matrix, a squared distances matrix, an inner-products matrix or computed from observed predictors.

Estimates Two-way Fixed Effects difference-in-differences/event-study models using the imputation-based approach proposed by Borusyak, Jaravel, and Spiess (2021).

This package provides density, distribution function, quantile function and random generation for the split normal and split-t distributions, and computes their mean, variance, skewness and kurtosis for the two distributions (Li, F, Villani, M. and Kohn, R. (2010) <doi:10.1016/j.jspi.2010.04.031>).

This package provides robustness checks to align estimands with the identification that they require. Given a dagitty object and a model specification, DAGassist classifies variables by causal roles, recovers a target estimand, and generates a report comparing the original model with DAG-derived adjustment sets. Exports publication-grade reports in LaTeX', Word', Excel', dotwhisker', or plain text/'markdown'. DAGassist is built on dagitty', an R package that uses the DAGitty web tool (<https://dagitty.net/>) for creating and analyzing DAGs. Methods draw on Pearl (2009) <doi:10.1017/CBO9780511803161> and Textor et al. (2016) <doi:10.1093/ije/dyw341>.

Dynamic slicing is a method designed for dependency detection between a categorical variable and a continuous variable. It could be applied for non-parametric hypothesis testing and gene set enrichment analysis.

Programmatic interface to the Daymet web services (<http://daymet.ornl.gov>). Allows for easy downloads of Daymet climate data directly to your R workspace or your computer. Routines for both single pixel data downloads and gridded (netCDF) data are provided.

This hosts the findRFM function which generates RFM scores on a 1-5 point scale for customer transaction data. The function consumes a data frame with Transaction Number, Customer ID, Date of Purchase (in date format) and Amount of Purchase as the attributes. The function returns a data frame with RFM data for the sales information.

Estimates the local average treatment effect (LATE) and the local average treatment effect on the treated (LATT) using observational data with a binary instrument, implementing the complete estimator suite of Sloczynski, Uysal, and Wooldridge: the doubly robust estimators of Sloczynski, Uysal, and Wooldridge (2022) <doi:10.48550/arXiv.2208.01300> -- inverse probability weighted regression adjustment (IPWRA), inverse probability weighting (IPW), augmented inverse probability weighting (AIPW), and regression adjustment (RA) -- and the Abadie-kappa weighting estimators of Sloczynski, Uysal, and Wooldridge (2025) <doi:10.1080/07350015.2024.2332763>. Supports linear, logistic, probit, Poisson, and fractional (fractional-logit and fractional-probit) outcome and treatment models, and instrument propensity scores estimated by maximum likelihood, covariate balancing (CBPS), or inverse probability tilting (IPT). Standard errors are computed jointly for all estimation stages by stacking the moment conditions of every model into a single M-estimation system; weak-instrument-robust Fieller confidence sets, cluster-aware bootstrap inference, design diagnostics, and a doubly robust Hausman-type test of unconfoundedness are included. Estimates and standard errors are validated against the authors Stata commands drlate (Statistical Software Components S459708) and kappalate (S459257).

This package provides functionality for users who are learning R or the techniques of data analysis. Written as a collection of wrapper functions, the DTwrapper package facilitates many core operations of data processing. This is achieved with relatively few requirements about the order of the processing steps or knowledge of specialized syntax. DTwrappers creates coding results along with translations to data.table's code. This enables users to benefit from the speed and efficiency of data.table's calculations. Furthermore, the package also provides the translated code for educational purposes so that users can review working examples of coding syntax and calculations.

Estimates latent variables of public opinion cross-nationally and over time from sparse and incomparable survey data. DCPO uses a population-level graded response model with country-specific item bias terms. Sampling is conducted with Stan'. References: Solt (2020) <doi:10.31235/osf.io/d5n9p>.

Fit a Poisson regression to carcass distance data and integrate over the searched area at a wind farm to estimate the fraction of carcasses falling in the searched area and format the output for use as the dwp parameter in the GenEst or eoa package for estimating bird and bat mortality, following Dalthorp, et al. (2024) <doi:10.3133/tm7A3>.

This package provides an R interface for downloading and standardizing election data to support research workflows. Election results are published by states through heterogeneous and often dynamic web interfaces that are not consistently accessible through existing R packages or APIs. To address this, the package wraps state-specific Python web scrapers through the reticulate package, enabling access to dynamic content while exposing consistent R functions for querying election availability and results across jurisdictions. The package is intended for responsible use and relies on publicly accessible election result pages.

This package provides landscape genomic functions to analyse SNP (single nuclear polymorphism) data, such as least cost path analysis and isolation by distance. Therefore each sample needs to have coordinate data attached (lat/lon) to be able to run most of the functions. dartR.spatial is a package that belongs to the dartRverse suit of packages and depends on dartR.base and dartR.data'.