Generating and validating One-time Password based on Hash-based Message Authentication Code (HOTP) and Time Based One-time Password (TOTP) according to RFC 4226 <https://datatracker.ietf.org/doc/html/rfc4226> and RFC 6238 <https://datatracker.ietf.org/doc/html/rfc6238>.

This package provides methods for determining optimum plot size and shape in field experiments using Fairfield-Smith's variance law approach. It will evaluate field variability, determine optimum plot size and shape and study fertility trends across the field.

This package provides a client that grants access to the power of the ohsome API from R. It lets you analyze the rich data source of the OpenStreetMap (OSM) history. You can retrieve the geometry of OSM data at specific points in time, and you can get aggregated statistics on the evolution of OSM elements and specify your own temporal, spatial and/or thematic filters.

Open Location Codes <http://openlocationcode.com/> are a Google-created standard for identifying geographic locations. olctools provides utilities for validating, encoding and decoding entries that follow this standard.

Computes A-, MV-, D- and E-optimal or near-optimal block designs for two-colour cDNA microarray experiments using the linear fixed effects and mixed effects models where the interest is in a comparison of all possible elementary treatment contrasts. The algorithms used in this package are based on the treatment exchange and array exchange algorithms of Debusho, Gemechu and Haines (2018) <doi:10.1080/03610918.2018.1429617>. The package also provides an optional method of using the graphical user interface (GUI) R package tcltk to ensure that it is user friendly.

This package provides tools for processing and analyzing data from the O-GlcNAcAtlas database <https://oglcnac.org/>, as described in Ma (2021) <doi:10.1093/glycob/cwab003>. It integrates UniProt <https://www.uniprot.org/> API calls to retrieve additional information. It is specifically designed for research workflows involving O-GlcNAcAtlas data, providing a flexible and user-friendly interface for customizing and downloading processed results. Interactive elements allow users to easily adjust parameters and handle various biological datasets.

This package provides a unified object-oriented framework for numerical optimizers in R. Allows for both minimization and maximization with any optimizer, optimization over more than one function argument, measuring of computation time, setting a time limit for long optimization tasks.

This package provides an interface to OpenCL, allowing R to leverage computing power of GPUs and other HPC accelerator devices.

Different measures which can be used to quantify similarities between regions. These measures are isonymy, isonymy between, Lasker distance, coefficients of Hedrick and Nei. In addition, it calculates biodiversity indices such as Margalef, Menhinick, Simpson, Shannon, Shannon-Wiener, Sheldon, Heip, Hill Numbers, Geometric Mean and Cressie and Read statistics.

Three-dimensional rendering for grid and ggplot2 graphics using cubes and cuboids drawn with an oblique projection. As a special case also supports primary view orthographic projections. Can be viewed as an extension to the isocubes package <https://github.com/coolbutuseless/isocubes>.

Estimates rates for continuous character evolution under Brownian motion and a new set of Ornstein-Uhlenbeck based Hansen models that allow both the strength of the pull and stochastic motion to vary across selective regimes. Beaulieu et al (2012).

The restricted optimal design method is implemented to optimally allocate a set of items that require calibration to a group of examinees. The optimization process is based on the method described in detail by Ul Hassan and Miller in their works published in (2019) <doi:10.1177/0146621618824854> and (2021) <doi:10.1016/j.csda.2021.107177>. To use the method, preliminary item characteristics must be provided as input. These characteristics can either be expert guesses or based on previous calibration with a small number of examinees. The item characteristics should be described in the form of parameters for an Item Response Theory (IRT) model. These models can include the Rasch model, the 2-parameter logistic model, the 3-parameter logistic model, or a mixture of these models. The output consists of a set of rules for each item that determine which examinees should be assigned to each item. The efficiency or gain achieved through the optimal design is quantified by comparing it to a random allocation. This comparison allows for an assessment of how much improvement or advantage is gained by using the optimal design approach. This work was supported by the Swedish Research Council (Vetenskapsrådet) Grant 2019-02706.

Many treatment effect estimators can be written as weighted outcomes. These weights have established use cases like checking covariate balancing via packages like cobalt'. This package takes the original estimator objects and outputs these outcome weights. It builds on the general framework of Knaus (2024) <doi:10.48550/arXiv.2411.11559>. This version is compatible with the grf package and provides an internal implementation of Double Machine Learning.

The algorithm first identifies a population of individuals from Danish register data with any type of diabetes as individuals with two or more inclusion events. Then, it splits this population into individuals with either type 1 diabetes or type 2 diabetes by identifying individuals with type 1 diabetes and classifying the remainder of the diabetes population as having type 2 diabetes.

R bindings to odiff', a blazing-fast pixel-by-pixel image comparison tool <https://github.com/dmtrKovalenko/odiff>. Supports PNG, JPEG, WEBP, and TIFF with configurable thresholds, antialiasing detection, and region ignoring. Requires system installation of odiff'. Ideal for visual regression testing in automated workflows.

An unofficial wrapper for okx exchange v5 API <https://www.okx.com/docs-v5/en/>, including REST API and WebSocket API.

This package provides a database containing the names of the babies born in Ontario between 1917 and 2018. Counts of fewer than 5 names were suppressed for privacy.

Useful functions for one-sample (individual level data) Mendelian randomization and instrumental variable analyses. The package includes implementations of; the Sanderson and Windmeijer (2016) <doi:10.1016/j.jeconom.2015.06.004> conditional F-statistic, the multiplicative structural mean model Hernán and Robins (2006) <doi:10.1097/01.ede.0000222409.00878.37>, and two-stage predictor substitution and two-stage residual inclusion estimators explained by Terza et al. (2008) <doi:10.1016/j.jhealeco.2007.09.009>.

Functionality to handle and project lat-long coordinates, easily download background maps and add a correct scale bar to OpenStreetMap plots in any map projection.

Interact seamlessly with Open Target GraphQL endpoint to query and retrieve tidy data tables, facilitating the analysis of gene, disease, drug, and genetic data. For more information about the Open Target API (<https://platform.opentargets.org/api>).

The Open University Learning Analytics Dataset (OULAD) is available from Kuzilek et al. (2017) <doi:10.1038/sdata.2017.171>. The ouladFormat package loads, cleans and formats the OULAD for data analysis (each row of the returned data set is an individual student). The packageâ s main function, combined_dataset(), allows the user to choose whether the returned data set includes assessment, demographics, virtual learning environment (VLE), or registration variables etc.

For the problem of indirect treatment comparison with limited subject-level data, this package provides tools for model-based standardisation with several different computation approaches. See Remiroâ Azócar A, Heath A, Baio G (2022) "Parametric Gâ computation for compatible indirect treatment comparisons with limited individual patient data", Res. Synth. Methods, 1â 31. ISSN 1759-2879, <doi:10.1002/jrsm.1565>.

Microarray probe ID is not convenient for further enrichment analysis and target gene selection. The package is created for the rice microarray probe ID conversion. This package can convert microarray probe ID from GPL6864 <https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL6864>, GPL8852 <https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL8852>, and GPL2025 <https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL2025> platforms to RAP-DB ID. RAP-DB "The Rice Annotation Project Database" <https://rapdb.dna.affrc.go.jp> is a well-known database for rice Oryza sativa, and the gene ID in this database is widely used in many areas related to rice research. For multiple probes representing a single gene, This package can merge them by taking the mean, max, or min value of these probes. Or we can keep multiple probes by appending sequence numbers to duplicate the RAP-DB ID.

This package provides a set of standard benchmark optimization functions for R and a common interface to sample them.