This package provides Partial least squares Regression and various regular, sparse or kernel, techniques for fitting Cox models in high dimensional settings <doi:10.1093/bioinformatics/btu660>, Bastien, P., Bertrand, F., Meyer N., Maumy-Bertrand, M. (2015), Deviance residuals-based sparse PLS and sparse kernel PLS regression for censored data, Bioinformatics, 31(3):397-404. Cross validation criteria were studied in <doi:10.48550/arXiv.1810.02962>, Bertrand, F., Bastien, Ph. and Maumy-Bertrand, M. (2018), Cross validating extensions of kernel, sparse or regular partial least squares regression models to censored data.

Fast estimation of binomial spatial probit regression models with spatial autocorrelation for big datasets.

This package provides a testing workbench to evaluate tools that calculate precision-recall curves. Saito and Rehmsmeier (2015) <doi:10.1371/journal.pone.0118432>.

Implementations of algorithms from Learning Sparse Penalties for Change-point Detection using Max Margin Interval Regression, by Hocking, Rigaill, Vert, Bach <http://proceedings.mlr.press/v28/hocking13.html> published in proceedings of ICML2013.

Following Sommer (2022) <https://mediatum.ub.tum.de/1658240> portfolio level risk estimates (e.g. Value at Risk, Expected Shortfall) are estimated by modeling each asset univariately by an ARMA-GARCH model and then their cross dependence via a Vine Copula model in a rolling window fashion. One can even condition on variables/time series at certain quantile levels to stress test the risk measure estimates.

This package provides an interface to the GenderAPI.io Phone Number Validation & Formatter API (<https://www.genderapi.io>) for validating international phone numbers, detecting number type (mobile, landline, Voice over Internet Protocol (VoIP)), retrieving region and country metadata, and formatting numbers to E.164 or national format. Designed to simplify integration into R workflows for data validation, Customer Relationship Management (CRM) data cleaning, and analytics tasks. Full documentation is available at <https://www.genderapi.io/docs-phone-validation-formatter-api>.

This package implements the primePCA algorithm, developed and analysed in Zhu, Z., Wang, T. and Samworth, R. J. (2019) High-dimensional principal component analysis with heterogeneous missingness. <arXiv:1906.12125>.

This package provides a multiway method to decompose a tensor (array) of any order, as a generalisation of SVD also supporting non-identity metrics and penalisations. 2-way SVD with these extensions is also available. The package includes also some other multiway methods: PCAn (Tucker-n) and PARAFAC/CANDECOMP with these extensions.

Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via MERLIN (Abecasis et al. (2002) <doi:10.1038/ng786>), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. paramlink2 is part of the pedsuite package ecosystem, presented in Pedigree Analysis in R (Vigeland, 2021, ISBN:9780128244302).

This package provides Partial least squares Regression for (weighted) beta regression models (Bertrand 2013, <https://ojs-test.apps.ocp.math.cnrs.fr/index.php/J-SFdS/article/view/215>) and k-fold cross-validation of such models using various criteria. It allows for missing data in the explanatory variables. Bootstrap confidence intervals constructions are also available.

This package implements estimation and testing procedures for evaluating an intermediate biomarker response as a principal surrogate of a clinical response to treatment (i.e., principal stratification effect modification analysis), as described in Juraska M, Huang Y, and Gilbert PB (2020), Inference on treatment effect modification by biomarker response in a three-phase sampling design, Biostatistics, 21(3): 545-560 <doi:10.1093/biostatistics/kxy074>. The methods avoid the restrictive placebo structural risk modeling assumption common to past methods and further improve robustness by the use of nonparametric kernel smoothing for biomarker density estimation. A randomized controlled two-group clinical efficacy trial is assumed with an ordered categorical or continuous univariate biomarker response measured at a fixed timepoint post-randomization and with a univariate baseline surrogate measure allowed to be observed in only a subset of trial participants with an observed biomarker response (see the flexible three-phase sampling design in the paper for details). Bootstrap-based procedures are available for pointwise and simultaneous confidence intervals and testing of four relevant hypotheses. Summary and plotting functions are provided for estimation results.

This package provides a collection of functions to process digital images, depict greenness index trajectories and extract relevant phenological stages.

This provides utilities for creating classed error and warning conditions based on where the error originated.

Parsimonious Ultrametric Gaussian Mixture Models via grouped coordinate ascent (equivalent to EM) algorithm characterized by the inspection of hierarchical relationships among variables via parsimonious extended ultrametric covariance structures. The methodologies are described in Cavicchia, Vichi, Zaccaria (2024) <doi:10.1007/s11222-024-10405-9>, (2022) <doi:10.1007/s11634-021-00488-x> and (2020) <doi:10.1007/s11634-020-00400-z>.

PROMETHEE (Preference Ranking Organisation METHod for Enrichment of Evaluations) based method assesses alternatives to obtain partial and complete rankings. The package also provides the GLNF (Global Local Net Flow) sorting algorithm to classify alternatives into ordered categories, as well as an index function to measure the classification quality. Barrera, F., Segura, M., & Maroto, C. (2023) <doi:10.1111/itor.13288>. Brans, J.P.; De Smet, Y., (2016) <doi:10.1007/978-1-4939-3094-4_6>.

This package provides functions to simulate point prevalence studies (PPSs) of healthcare-associated infections (HAIs) and to convert prevalence to incidence in steady state setups. Companion package to the preprint Willrich et al., From prevalence to incidence - a new approach in the hospital setting; <doi:10.1101/554725> , where methods are explained in detail.

This package provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.

Translates beliefs into prior information in the form of Beta and Gamma distributions. It can be used for the generation of priors on the prevalence of disease and the sensitivity/specificity of diagnostic tests and any other binomial experiment.

Convert Chinese characters into Pinyin (the official romanization system for Standard Chinese in mainland China, Malaysia, Singapore, and Taiwan. See <https://en.wikipedia.org/wiki/Pinyin> for details), Sijiao (four or five numerical digits per character. See <https://en.wikipedia.org/wiki/Four-Corner_Method>.), Wubi (an input method with five strokes. See <https://en.wikipedia.org/wiki/Wubi_method>) or user-defined codes.

Implementation of the exact, normal approximation, and simulation-based methods for computing the probability mass function (pmf) and cumulative distribution function (cdf) of the Poisson-Multinomial distribution, together with a random number generator for the distribution. The exact method is based on multi-dimensional fast Fourier transformation (FFT) of the characteristic function of the Poisson-Multinomial distribution. The normal approximation method uses a multivariate normal distribution to approximate the pmf of the distribution based on central limit theorem. The simulation method is based on the law of large numbers. Details about the methods are available in Lin, Wang, and Hong (2022) <DOI:10.1007/s00180-022-01299-0>.

This utility eases the debugging of literate documents ('noweb files) by patching the synchronization information (the .synctex(.gz) file) produced by pdflatex with concordance information produced by Sweave or knitr and Sweave or knitr ; this allows for bilateral communication between a text editor (visualizing the noweb source) and a viewer (visualizing the resultant PDF'), thus bypassing the intermediate TeX file.

Computes penalized regression calibration (PRC), a statistical method for the dynamic prediction of survival when many longitudinal predictors are available. See Signorelli (2024) <doi:10.32614/RJ-2024-014> and Signorelli et al. (2021) <doi:10.1002/sim.9178> for details.

This package provides a new metric named dependency heaviness is proposed that measures the number of additional dependency packages that a parent package brings to its child package and are unique to the dependency packages imported by all other parents. The dependency heaviness analysis is visualized by a customized heatmap. The package is described in <doi:10.1093/bioinformatics/btac449>. We have also performed the dependency heaviness analysis on the CRAN/Bioconductor package ecosystem and the results are implemented as a web-based database which provides comprehensive tools for querying dependencies of individual R packages. The systematic analysis on the CRAN/Bioconductor ecosystem is described in <doi:10.1016/j.jss.2023.111610>. From pkgndep version 2.0.0, the heaviness database includes snapshots of the CRAN/Bioconductor ecosystems for many old R versions.

The package solves linear system of equations Ax=b by using Preconditioned Conjugate Gradient Algorithm where A is real symmetric positive definite matrix. A suitable preconditioner matrix may be provided by user. This can also be used to minimize quadratic function (x'Ax)/2-bx for unknown x.