Designed to create interactive and visually compelling network maps using R Shiny. It allows users to quickly analyze CSV files and visualize complex relationships, structures, and connections within data by leveraging powerful network analysis libraries and dynamic web interfaces.

This package provides a number of statistical tests have been proposed to compare two survival curves, including the difference in (or ratio of) t-year survival, difference in (or ratio of) p-th percentile survival, difference in (or ratio of) restricted mean survival time, and the weighted log-rank test. Despite the multitude of options, the convention in survival studies is to assume proportional hazards and to use the unweighted log-rank test for design and analysis. This package provides sample size and power calculation for all of the above statistical tests with allowance for flexible accrual, censoring, and survival (eg. Weibull, piecewise-exponential, mixture cure). It is the companion R package to the paper by Yung and Liu (2020) <doi:10.1111/biom.13196>. Specific to the weighted log-rank test, users may specify which approximations they wish to use to estimate the large-sample mean and variance. The default option has been shown to provide substantial improvement over the conventional sample size and power equations based on Schoenfeld (1981) <doi:10.1093/biomet/68.1.316>.

This package provides streamlined installation for packages from the natverse', a suite of R packages for computational neuroanatomy built on top of the nat NeuroAnatomy Toolbox package. Installation of the complete natverse suite requires a GitHub user account and personal access token GITHUB_PAT'. natmanager will help the end user set this up if necessary.

Fits non-homogeneous Markov multistate models and misclassification-type hidden Markov models in continuous time to intermittently observed data. Implements the methods in Titman (2011) <doi:10.1111/j.1541-0420.2010.01550.x>. Uses direct numerical solution of the Kolmogorov forward equations to calculate the transition probabilities.

Datasets and functions to benchmark (convergence, speed, ease of use) R packages dedicated to regression with neural networks (no classification in this version). The templates for the tested packages are available in the R, R Markdown and HTML formats at <https://github.com/pkR-pkR/NNbenchmarkTemplates> and <https://theairbend3r.github.io/NNbenchmarkWeb/index.html>. The submitted article to the R-Journal can be read at <https://www.inmodelia.com/gsoc2020.html>.

Create and manipulate numeric list ('nlist') objects. An nlist is an S3 list of uniquely named numeric objects. An numeric object is an integer or double vector, matrix or array. An nlists object is a S3 class list of nlist objects with the same names, dimensionalities and typeofs. Numeric list objects are of interest because they are the raw data inputs for analytic engines such as JAGS', STAN and TMB'. Numeric lists objects, which are useful for storing multiple realizations of of simulated data sets, can be converted to coda::mcmc and coda::mcmc.list objects.

This package provides tools for estimating Receiver Operating Characteristic (ROC) curves, building confidence bands, comparing several curves both for dependent and independent data, estimating the cumulative-dynamic ROC curve in presence of censored data, and performing meta-analysis studies, among others.

Offers a rich and diverse collection of datasets focused on the brain, nervous system, and related disorders. The package includes clinical, experimental, neuroimaging, behavioral, cognitive, and simulated data on conditions such as Parkinson's disease, Alzheimer's, epilepsy, schizophrenia, gliomas, and mental health. Datasets cover structural and functional brain data, neurotransmission, gene expression, cognitive performance, and treatment outcomes. Designed for researchers, neuroscientists, clinicians, psychologists, data scientists, and students, this package facilitates exploratory data analysis, statistical modeling, and hypothesis testing in neuroscience and neuroepidemiology.

Plot, process, and analyze NPO files produced by Nonpareil <http://enve-omics.ce.gatech.edu/nonpareil/>.

Assist novice developers when preparing a single package or a set of integrated packages to submit to CRAN. Automate the following individual or batch processing: check local source packages; build local .tar.gz source files; install packages from local .tar.gz files; detect conflicts between function names in the environment.

This package provides functions for revealing what happens when effect size estimates from previous studies are taken into account when evaluating each new dataset in a study sequence. The analyses can be conducted for cumulative meta-analyses and for Bayesian data analyses. The package contains sample data for a wide selection of research topics. Jointly considering previous findings along with new data is more likely to result in correct conclusions than does the traditional practice of not incorporating previous findings, which often results in a back and forth ping-pong of conclusions when evaluating a sequence of studies. O'Connor & Ermacora (2021, <doi:10.1037/cbs0000259>).

In empirical studies, instrumental variable (IV) regression is the signature method to solve the endogeneity problem. If we enforce the exogeneity condition of the IV, it is likely that we end up with a large set of IVs without knowing which ones are good. Also, one could face the model uncertainty for structural equation, as large micro dataset is commonly available nowadays. This package uses adaptive group lasso and B-spline methods to select the nonparametric components of the IV function, with the linear function being a special case (naivereg). The package also incorporates two stage least squares estimator (2SLS), generalized method of moment (GMM), generalized empirical likelihood (GEL) methods post instrument selection, logistic-regression instrumental variables estimator (LIVE, for dummy endogenous variable problem), double-selection plus instrumental variable estimator (DS-IV) and double selection plus logistic regression instrumental variable estimator (DS-LIVE), where the double selection methods are useful for high-dimensional structural equation models. The naivereg is nonparametric version of ivregress in Stata with IV selection and high dimensional features. The package is based on the paper by Q. Fan and W. Zhong, "Nonparametric Additive Instrumental Variable Estimator: A Group Shrinkage Estimation Perspective" (2018), Journal of Business & Economic Statistics <doi:10.1080/07350015.2016.1180991> as well as a series of working papers led by the same authors.

The Dirichlet (aka NBD-Dirichlet) model describes the purchase incidence and brand choice of consumer products. We estimate the model and summarize various theoretical quantities of interest to marketing researchers. Also provides functions for making tables that compare observed and theoretical statistics.

The Nordklim dataset 1.0 is a unique and useful achievement for climate analysis. It includes observations of twelve different climate elements from more than 100 stations in the Nordic region, in time span over 100 years. The project contractors were NORDKLIM/NORDMET on behalf of the National meteorological services in Denmark (DMI), Finland (FMI), Iceland (VI), Norway (DNMI) and Sweden (SMHI).

This package provides a JAGS extension module provides neo-normal distributions family including MSNBurr, MSNBurr-IIa, GMSNBurr, Lunetta Exponential Power, Fernandez-Steel Skew t, Fernandez-Steel Skew Normal, Fernandez-Osiewalski-Steel Skew Exponential Power, Jones Skew Exponential Power. References: Choir, A. S. (2020). "The New Neo-Normal Distributions and Their Properties".Unpublished Dissertation. Denwood, M.J. (2016) <doi:10.18637/jss.v071.i09>. Fernandez, C., Osiewalski, J., & Steel, M. F. (1995) <doi:10.1080/01621459.1995.10476637>. Fernandez, C., & Steel, M. F. (1998) <doi:10.1080/01621459.1998.10474117>. Iriawan, N. (2000). "Computationally Intensive Approaches to Inference in NeoNormal Linear Models".Unpublished Dissertation. Mineo, A., & Ruggieri, M. (2005) <doi:10.18637/jss.v012.i04>. Rigby, R. A., & Stasinopoulos, D. M. (2005) <doi:10.1111/j.1467-9876.2005.00510.x>. Lunetta, G. (1963). "Di una Generalizzazione dello Schema della Curva Normale". Rigby, R. A., Stasinopoulos, M. D., Heller, G. Z., & Bastiani, F. D. (2019) <doi:10.1201/9780429298547>.

Fast and Accurate Trisomy Prediction in Non-Invasive Prenatal Testing.

This package provides statistical methods for network meta-analysis of 1â 5 diagnostic tests to simultaneously compare multiple tests within a missing data framework, including: - Bayesian hierarchical model for network meta-analysis of multiple diagnostic tests (Ma, Lian, Chu, Ibrahim, and Chen (2018) <doi:10.1093/biostatistics/kxx025>) - Bayesian Hierarchical Summary Receiver Operating Characteristic Model for Network Meta-Analysis of Diagnostic Tests (Lian, Hodges, and Chu (2019) <doi:10.1080/01621459.2018.1476239>).

NNS (Nonlinear Nonparametric Statistics) leverages partial moments â the fundamental elements of variance that asymptotically approximate the area under f(x) â to provide a robust foundation for nonlinear analysis while maintaining linear equivalences. NNS delivers a comprehensive suite of advanced statistical techniques, including: Numerical integration, Numerical differentiation, Clustering, Correlation, Dependence, Causal analysis, ANOVA, Regression, Classification, Seasonality, Autoregressive modeling, Normalization, Stochastic dominance and Advanced Monte Carlo sampling. All routines based on: Viole, F. and Nawrocki, D. (2013), Nonlinear Nonparametric Statistics: Using Partial Moments (ISBN: 1490523995).

This package performs combination tests and sample size calculation for fixed design with survival endpoints using combination tests under either proportional hazards or non-proportional hazards. The combination tests include maximum weighted log-rank test and projection test. The sample size calculation procedure is very flexible, allowing for user-defined hazard ratio function and considering various trial conditions like staggered entry, drop-out etc. The sample size calculation also applies to various cure models such as proportional hazards cure model, cure model with (random) delayed treatments effects. Trial simulation function is also provided to facilitate the empirical power calculation. The references for projection test and maximum weighted logrank test include Brendel et al. (2014) <doi:10.1111/sjos.12059> and Cheng and He (2021) <arXiv:2110.03833>. The references for sample size calculation under proportional hazard include Schoenfeld (1981) <doi:10.1093/biomet/68.1.316> and Freedman (1982) <doi:10.1002/sim.4780010204>. The references for calculation under non-proportional hazards include Lakatos (1988) <doi:10.2307/2531910> and Cheng and He (2023) <doi:10.1002/bimj.202100403>.

Non linear dot plots are diagrams that allow dots of varying size to be constructed, so that columns with a large number of samples are reduced in height. Implementation of algorithm described in: Nils Rodrigues and Daniel Weiskopf, "Nonlinear Dot Plots", IEEE Transactions on Visualization and Computer Graphics, vol. 24, no. 1, pp. 616-625, 2018. <doi:10.1109/TVCG.2017.2744018>.

Estimating the number of essential genes in a genome on the basis of data from a random transposon mutagenesis experiment, through the use of a Gibbs sampler. Lamichhane et al. (2003) <doi:10.1073/pnas.1231432100>.

This package provides number-theoretic functions for factorization, prime numbers, twin primes, primitive roots, modular logarithm and inverses, extended GCD, Farey series and continued fractions. Includes Legendre and Jacobi symbols, some divisor functions, Euler's Phi function, etc.

This package provides functions to fit linear mixed models based on convolutions of the generalized Laplace (GL) distribution. The GL mixed-effects model includes four special cases with normal random effects and normal errors (NN), normal random effects and Laplace errors (NL), Laplace random effects and normal errors (LN), and Laplace random effects and Laplace errors (LL). The methods are described in Geraci and Farcomeni (2020, Statistical Methods in Medical Research) <doi:10.1177/0962280220903763>.

Analysis functions to quantify inputs importance in neural network models. Functions are available for calculating and plotting the inputs importance and obtaining the activation function of each neuron layer and its derivatives. The importance of a given input is defined as the distribution of the derivatives of the output with respect to that input in each training data point <doi:10.18637/jss.v102.i07>.