It's a Modern K-Means clustering algorithm which works for data of any number of dimensions, has no limit with the number of clusters expected, offers both methods with and without initial cluster centers, and can start with any initial cluster centers for the method with initial cluster centers.

Fits multi-way component models via alternating least squares algorithms with optional constraints. Fit models include N-way Canonical Polyadic Decomposition, Individual Differences Scaling, Multiway Covariates Regression, Parallel Factor Analysis (1 and 2), Simultaneous Component Analysis, and Tucker Factor Analysis.

Fits and tests meta regression models and generates a number of useful test statistics: next to t- and z-tests, the likelihood ratio, bartlett corrected likelihood ratio and permutation tests are performed on the model coefficients.

To assess a summary survival curve from survival probabilities and number of at-risk patients collected at various points in time in various studies, and to test the between-strata heterogeneity.

Used for general multiple mediation analysis. The analysis method is described in Yu and Li (2022) (ISBN: 9780367365479) "Statistical Methods for Mediation, Confounding and Moderation Analysis Using R and SAS", published by Chapman and Hall/CRC; and Yu et al.(2017) <DOI:10.1016/j.sste.2017.02.001> "Exploring racial disparity in obesity: a mediation analysis considering geo-coded environmental factors", published on Spatial and Spatio-temporal Epidemiology, 21, 13-23.

This package provides tools to simulate morphological traits along phylogenetic trees with branch lengths representing evolutionary distance or time. Includes functions for visualizing evolutionary processes along trees and within morphological character matrices.

An interactive application to visualise meta-analysis data as a physical weighing machine. The interface is based on the Shiny web application framework, though can be run locally and with the user's own data.

BEAST2 (<https://www.beast2.org>) is a widely used Bayesian phylogenetic tool, that uses DNA/RNA/protein data and many model priors to create a posterior of jointly estimated phylogenies and parameters. BEAST2 is commonly accompanied by BEAUti 2 (<https://www.beast2.org>), which, among others, allows one to install BEAST2 package. This package allows to work with BEAST2 packages from R'.

This package performs treatment allocation in two-arm clinical trials by the maximal procedure described by Berger et al. (2003) <doi:10.1002/sim.1538>. To that end, the algorithm provided by Salama et al. (2008) <doi:10.1002/sim.3014> is implemented.

Estimation methods for phase-type distribution (PH) and Markovian arrival process (MAP) from empirical data (point and grouped data) and density function. The tool is based on the following researches: Okamura et al. (2009) <doi:10.1109/TNET.2008.2008750>, Okamura and Dohi (2009) <doi:10.1109/QEST.2009.28>, Okamura et al. (2011) <doi:10.1016/j.peva.2011.04.001>, Okamura et al. (2013) <doi:10.1002/asmb.1919>, Horvath and Okamura (2013) <doi:10.1007/978-3-642-40725-3_10>, Okamura and Dohi (2016) <doi:10.15807/jorsj.59.72>.

This package provides a collection of functions for processing and analyzing metabolite data. The namesake function mrbin() converts 1D or 2D Nuclear Magnetic Resonance data into a matrix of values suitable for further data analysis and performs basic processing steps in a reproducible way. Negative values, a common issue in such data, can be replaced by positive values (<doi:10.1021/acs.jproteome.0c00684>). All used parameters are stored in a readable text file and can be restored from that file to enable exact reproduction of the data at a later time. The function fia() ranks features according to their impact on classifier models, especially artificial neural network models.

This package provides a set of functions to investigate raw data from (metabol)omics experiments intended to be used on a raw data matrix, i.e. following peak picking and signal deconvolution. Functions can be used to normalize data, detect biomarkers and perform sample classification. A detailed description of best practice usage may be found in the publication <doi:10.1007/978-1-4939-7819-9_20>.

Administrative Boundaries of Spain at several levels (Autonomous Communities, Provinces, Municipalities) based on the GISCO Eurostat database <https://ec.europa.eu/eurostat/web/gisco> and CartoBase SIANE from Instituto Geografico Nacional <https://www.ign.es/>. It also provides a leaflet plugin and the ability of downloading and processing static tiles.

Generates internet memes that optionally include a superimposed inset plot and other atypical features, combining the visual impact of an attention-grabbing meme with graphic results of data analysis. The package differs from related packages that focus on imitating and reproducing standard memes. Some packages do this by interfacing with online meme generators whereas others achieve this natively. This package takes the latter approach. It does not interface with online meme generators or require any authentication with external websites. It reads images directly from local files or via URL and meme generation is done by the package. While this is similar to the meme package available on CRAN, it differs in that the focus is on allowing for non-standard meme layouts and hybrids of memes mixed with graphs. While this package can be used to make basic memes like an online meme generator would produce, it caters primarily to hybrid graph-meme plots where the meme presentation can be seen as a backdrop highlighting foreground graphs of data analysis results. The package also provides support for an arbitrary number of meme text labels with arbitrary size, position and other attributes rather than restricting to the standard top and/or bottom text placement. This is useful for proper aesthetic interleaving of plots of data between meme image backgrounds and overlain text labels. The package offers a selection of templates for graph placement and appearance with respect to the underlying meme. Graph templates also permit additional template-specific customization. Animated gif support is provided but this is optional and functional only if the magick package is installed. magick is not required unless gif functionality is desired.

Given a CSV file with titles and abstracts, the package creates a document-term matrix that is lemmatized and stemmed and can directly be used to train machine learning methods for automatic title-abstract screening in the preparation of a meta analysis.

Correct identification and handling of missing data is one of the most important steps in any analysis. To aid this process, mde provides a very easy to use yet robust framework to quickly get an idea of where the missing data lies and therefore find the most appropriate action to take. Graham WJ (2009) <doi:10.1146/annurev.psych.58.110405.085530>.

This package provides methods and tools for deriving spatial summary functions from single-cell imaging data and performing functional data analyses. Functions can be applied to other single-cell technologies such as spatial transcriptomics. Functional regression and functional principal component analysis methods are in the refund package <https://cran.r-project.org/package=refund> while calculation of the spatial summary functions are from the spatstat package <https://spatstat.org/>.

Provide a sample size calculator for micro-randomized trials (MRTs) based on methodology developed in Sample Size Calculations for Micro-randomized Trials in mHealth by Liao et al. (2016) <DOI:10.1002/sim.6847>.

This package provides a graphical user interface (GUI) for performing Multidimensional Scaling applications and interactively analysing the results all within the GUI environment. The MDS-GUI provides means of performing Classical Scaling, Least Squares Scaling, Metric SMACOF, Non-Metric SMACOF, Kruskal's Analysis and Sammon Mapping with animated optimisation.

This package provides an algorithm for creating mandalas. From the perspective of classic mathematical curves and rigid movements on the plane, the package allows you to select curves and produce mandalas from the curve. The algorithm was developed based on the book by Alcoforado et. al. entitled "Art, Geometry and Mandalas with R" (2022) in press by the USP Open Books Portal.

This package offers three important components: (1) to construct a use-defined linear mixed model, (2) to employ one of linear mixed model approaches: minimum norm quadratic unbiased estimation (MINQUE) (Rao, 1971) for variance component estimation and random effect prediction; and (3) to employ a jackknife resampling technique to conduct various statistical tests. In addition, this package provides the function for model or data evaluations.This R package offers fast computations for large data sets analyses for various irregular data structures.

Framework for the Item Response Theory analysis of dichotomous and ordinal polytomous outcomes under the assumption of multidimensionality and discreteness of the latent traits. The fitting algorithms allow for missing responses and for different item parameterizations and are based on the Expectation-Maximization paradigm. Individual covariates affecting the class weights may be included in the new version (since 2.1).

Selects bandwidth for the kernel density estimator with minimum distance method as proposed by Devroye and Lugosi (1996). The minimum distance method directly selects the optimal kernel density estimator from countably infinite kernel density estimators and indirectly selects the optimal bandwidth. This package selects the optimal bandwidth from finite kernel density estimators.

Colour palettes and helper functions for visualising Mycobacterium tuberculosis genomic and epidemiological data with ggplot2 and ggtree'. The package provides predefined palettes, scale functions, tree/cladogram helpers, and convenient preview tools to ensure consistent branding in pathogen-omics visualisations. The palettes were developed as part of the mycolorsTB project <https://github.com/PathoGenOmics-Lab/mycolorsTB>.