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The Australian Regulatory Guidelines for Prescription Medicines (ARGPM), guidance on "Stability testing for prescription medicines", recommends to predict the shelf life of chemically derived medicines from stability data by taking the worst case situation at batch release into account. Consequently, if a change over time is observed, a release limit needs to be specified. Finding a release limit and the associated shelf life is supported, as well as the standard approach that is recommended by guidance Q1E "Evaluation of stability data" from the International Council for Harmonisation (ICH).
Compute common data quality metrics for accuracy, precision and data loss for screen-based eye trackers. Supports input data both in pixels on the screen and in degrees, output measures are (where appropriate) expressed as angles in degrees.
This package provides tools for transforming R expressions. Provides functions for finding, extracting, and replacing patterns in R language objects, similarly to how regular expressions can be used to find, extract, and replace patterns in text. Also provides functions for generating code using specially-formatted template files and for translating R expressions into similar expressions in other programming languages. The package may be helpful for advanced uses of R expressions, such as developing domain-specific languages.
Density, distribution function, quantile function and random generation for the Kumaraswamy Complementary Weibull Geometric (Kw-CWG) lifetime probability distribution proposed in Afify, A.Z. et al (2017) <doi:10.1214/16-BJPS322>.
This package provides a fast, flexible tool for generating disease surveillance reports from data exported from EpiTrax', a central repository for epidemiological data used by public health officials. It provides functions to manipulate EpiTrax datasets, tailor reports to internal or public use, and export reports in CSV, Excel xlsx', or PDF formats.
Four ensemble-based methods (SMOTEBoost, RUSBoost, UnderBagging, and SMOTEBagging) for class imbalance problem are implemented for binary classification. Such methods adopt ensemble methods and data re-sampling techniques to improve model performance in presence of class imbalance problem. One special feature offers the possibility to choose multiple supervised learning algorithms to build weak learners within ensemble models. References: Nitesh V. Chawla, Aleksandar Lazarevic, Lawrence O. Hall, and Kevin W. Bowyer (2003) <doi:10.1007/978-3-540-39804-2_12>, Chris Seiffert, Taghi M. Khoshgoftaar, Jason Van Hulse, and Amri Napolitano (2010) <doi:10.1109/TSMCA.2009.2029559>, R. Barandela, J. S. Sanchez, R. M. Valdovinos (2003) <doi:10.1007/s10044-003-0192-z>, Shuo Wang and Xin Yao (2009) <doi:10.1109/CIDM.2009.4938667>, Yoav Freund and Robert E. Schapire (1997) <doi:10.1006/jcss.1997.1504>.
An RStudio addin for editing a data.frame or a tibble'. You can delete, add or update a data.frame without coding. You can get resultant data as a data.frame'. In the package, modularized shiny app codes are provided. These modules are intended for reuse across applications.
Some utility functions for validation and data manipulation. These functions can be helpful to reduce internal codes everywhere in package development.
This package provides a collection of curated educational datasets for teaching ecology and agriculture concepts. Includes data on wildlife monitoring, plant treatments, and ecological observations with documentation and examples for educational use. All datasets are derived from published scientific studies and are available under CC0 or compatible licenses.
In the USA, companies file different forms with the U.S. Securities and Exchange Commission (SEC) through EDGAR (Electronic Data Gathering, Analysis, and Retrieval system). The EDGAR database automated system collects all the different necessary filings and makes it publicly available. This package facilitates retrieving, storing, searching, and parsing of all the available filings on the EDGAR server. It downloads filings from SEC server in bulk with a single query. Additionally, it provides various useful functions: extracts 8-K triggering events, extract "Business (Item 1)" and "Management's Discussion and Analysis(Item 7)" sections of annual statements, searches filings for desired keywords, provides sentiment measures, parses filing header information, and provides HTML view of SEC filings.
This package provides a system for importing electrophysiological signal, based on the Waveform Database (WFDB) software package, written by Moody et al 2022 <doi:10.13026/gjvw-1m31>. A R-based system to utilize WFDB functions for reading and writing signal data, as well as functions for visualization and analysis are provided. A stable and broadly compatible class for working with signal data, supporting the reading in of cardiac electrophysiological files such as intracardiac electrograms, is introduced.
An implementation for estimating Effective control to 50% of growth inhibition (EC50) for multi isolates and stratified datasets. It implements functions from the drc package in a way that is displayed a tidy data.frame as output. Info about the drc package is available in Ritz C, Baty F, Streibig JC, Gerhard D (2015) <doi:10.1371/journal.pone.0146021>.
This package provides functions that help with analysis of prognostic study data. This allows users with little experience of developing models to develop models and assess the performance of the prognostic models. This also summarises the information, so the performance of multiple models can be displayed simultaneously. This minor update fixes issues related to memory requirements with large number of simulations and deals with situations when there is overfitting of data. Gurusamy, K (2026)<https://github.com/kurinchi2k/EQUALPrognosis>.
Allows for forward-in-time simulation of epistatic networks with associated phenotypic output.
Analysis of experimental results and automatic report generation in both interactive HTML and LaTeX. This package ships with a rich interface for data modeling and built in functions for the rapid application of statistical tests and generation of common plots and tables with publish-ready quality.
This package provides a system to facilitate designing comparative (and non-comparative) experiments using the grammar of experimental designs <https://emitanaka.org/edibble-book/>. An experimental design is treated as an intermediate, mutable object that is built progressively by fundamental experimental components like units, treatments, and their relation. The system aids in experimental planning, management and workflow.
Life Table Response Experiments (LTREs) are a method of comparative demographic analysis. The purpose is to quantify how the difference or variance in vital rates (stage-specific survival, growth, and fertility) among populations contributes to difference or variance in the population growth rate, "lambda." We provide functions for one-way fixed design and random design LTRE, using either the classical methods that have been in use for several decades, or an fANOVA-based exact method that directly calculates the impact on lambda of changes in matrix elements, for matrix elements and their interactions. The equations and descriptions for the classical methods of LTRE analysis can be found in Caswell (2001, ISBN: 0878930965), and the fANOVA-based exact methods are described in Hernandez et al. (2023) <doi:10.1111/2041-210X.14065>. We also provide some demographic functions, including generation time from Bienvenu and Legendre (2015) <doi:10.1086/681104>. For implementation of exactLTRE where all possible interactions are calculated, we use an operator matrix presented in Poelwijk, Krishna, and Ranganathan (2016) <doi:10.1371/journal.pcbi.1004771>.
Expectile and quantile regression of models with nonlinear effects e.g. spatial, random, ridge using least asymmetric weighed squares / absolutes as well as boosting; also supplies expectiles for common distributions.
Fit models of modularity to morphological landmarks. Perform model selection on results. Fit models with a single within-module correlation or with separate within-module correlations fitted to each module.
Supports designing efficient discrete choice experiments (DCEs). Experimental designs can be formed on the basis of orthogonal arrays or search methods for optimal designs (Federov or mixed integer programs). Various methods for converting these experimental designs into a discrete choice experiment. Many efficiency measures! Draws from literature of Kuhfeld (2010) and Street et. al (2005) <doi:10.1016/j.ijresmar.2005.09.003>.
This package provides a tool to operate a batch of univariate or multivariate Cox models and return tidy result.
This package provides a data package containing a database of epidemiological parameters. It stores the data for the epiparameter R package. Epidemiological parameter estimates are extracted from the literature.
Estimate the effective reproduction number from wastewater and clinical data sources.
This package contains data about emojis with relevant metadata, and functions to work with emojis when they are in strings.