Perform sample size, power calculation and subsequent analysis for Immuno-oncology (IO) trials composed of responders and non-responders.

An open-source toolbox for storing, validating, managing, and exploring transportation infrastructure data. Provides a relational data model for binders, aggregates, mixtures, and test results, with a human-readable file format (.pavdata) aligned with FAIR principles.

Phylogenetic comparative methods represent models of continuous trait data associated with the tips of a phylogenetic tree. Examples of such models are Gaussian continuous time branching stochastic processes such as Brownian motion (BM) and Ornstein-Uhlenbeck (OU) processes, which regard the data at the tips of the tree as an observed (final) state of a Markov process starting from an initial state at the root and evolving along the branches of the tree. The PCMBase R package provides a general framework for manipulating such models. This framework consists of an application programming interface for specifying data and model parameters, and efficient algorithms for simulating trait evolution under a model and calculating the likelihood of model parameters for an assumed model and trait data. The package implements a growing collection of models, which currently includes BM, OU, BM/OU with jumps, two-speed OU as well as mixed Gaussian models, in which different types of the above models can be associated with different branches of the tree. The PCMBase package is limited to trait-simulation and likelihood calculation of (mixed) Gaussian phylogenetic models. The PCMFit package provides functionality for inference of these models to tree and trait data. The package web-site <https://venelin.github.io/PCMBase/> provides access to the documentation and other resources.

Provision of a set of models and methods for use in the allocation and management of capital in financial portfolios.

Calculating Pst values to assess differentiation among populations from a set of quantitative traits is the primary purpose of such a package. The bootstrap method provides confidence intervals and distribution histograms of Pst. Variations of Pst in function of the parameter c/h^2 are studied as well. Finally, the package proposes different transformations especially to eliminate any variation resulting from allometric growth (calculation of residuals from linear regressions, Reist standardizations or Aitchison transformation).

Palettes inspired by Paris 2024 Olympic and Paralympic Games for data visualizations. Length of color palettes is configurable.

Create a parallel coordinates plot, using `htmlwidgets` package and `d3.js`.

This package provides an easy-to-use yet adaptable set of tools to conduct person-center analysis using a two-step clustering procedure. As described in Bergman and El-Khouri (1999) <DOI:10.1002/(SICI)1521-4036(199910)41:6%3C753::AID-BIMJ753%3E3.0.CO;2-K>, hierarchical clustering is performed to determine the initial partition for the subsequent k-means clustering procedure.

Easy function for text-mining the PubMed repository based on defined sets of terms. The relationship between fix-terms (related to your research topic) and pub-terms (terms which pivot around your research focus) is calculated using the pointwise mutual information algorithm ('PMI'). Church, Kenneth Ward and Hanks, Patrick (1990) <https://www.aclweb.org/anthology/J90-1003/> A text file is generated with the PMI'-scores for each fix-term. Then for each collocation pairs (a fix-term + a pub-term), a text file is generated with related article titles and publishing years. Additional Author section will follow in the next version updates.

Interactively annotate base R graphics plots with freehand drawing, symbols (points, lines, arrows, rectangles, circles, ellipses), and text. This is useful for teaching, for example to visually explain certain plot elements, and creating quick sketches.

Computes sample size and power for causal inference studies that use propensity score (PS) weighting. Supports continuous, binary, and time-to-event (survival) outcomes under four estimands: average treatment effect (ATE), average treatment effect on the treated (ATT), average treatment effect on the controls (ATC), and average treatment effect on the overlap population (ATO). For continuous and binary outcomes, the asymptotic variance of the Hajek inverse probability weighting estimator is derived under a logit-normal propensity score model, approximated by a Beta distribution matched through the Bhattacharyya overlap coefficient. For survival outcomes, the asymptotic variance of the propensity-score- weighted partial likelihood estimator is used for randomized trials and observational studies. The Schoenfeld formula is also available for randomized trial settings.

This package provides a collection of easy-to-use tools for regression analysis of survival data with a cure fraction proposed in Su et al. (2022) <doi:10.1177/09622802221108579>. The modeling framework is based on the Cox proportional hazards mixture cure model and the bounded cumulative hazard (promotion time cure) model. The pseudo-observations approach is utilized to assess covariate effects and embedded in the variable selection procedure.

This package provides a fully legal chess move generator and game engine implemented in C++17 via Rcpp'. Provides FEN (Forsyth-Edwards Notation) parsing, PGN (Portable Game Notation) replay, position feature enrichment, and a multi-game registry backed by a bitboard representation.

Implement surrogate-assisted feature extraction (SAFE) and common machine learning approaches to train and validate phenotyping models. Background and details about the methods can be found at Zhang et al. (2019) <doi:10.1038/s41596-019-0227-6>, Yu et al. (2017) <doi:10.1093/jamia/ocw135>, and Liao et al. (2015) <doi:10.1136/bmj.h1885>.

This package implements the Penalized Youden Index Estimator (PYE) and the Covariate-Adjusted Youden Index Estimator (covYI), providing a novel framework for feature and covariate selection and combination in high-dimensional binary classification problems. Methodologies are based on Salaroli and Pardo (2023) <doi:10.1016/j.chemolab.2023.104786> and an unpublished manuscript by Salaroli and Pardo (2026) under review.

Based on (but not identical to) the no-longer-maintained package phyext', provides enhancements to phylobase classes, specifically for use by package SigTree'; provides classes and methods which help users manipulate branch-annotated trees (as in SigTree'); also provides support for a few other extra features.

Check a data frame for personal information, including names, location, disability status, and geo-coordinates.

Spatial Analysis for exploration of Pakistan Population Census 2017 (<https://www.pbs.gov.pk/content/population-census>). It uses data from R package PakPC2017'.

The PBIB designs are important type of incomplete block designs having wide area of their applications for example in agricultural experiments, in plant breeding, in sample surveys etc. This package constructs various series of PBIB designs and assists in checking all the necessary conditions of PBIB designs and the association scheme on which these designs are based on. It also assists in calculating the efficiencies of PBIB designs with any number of associate classes. The package also constructs Youden-m square designs which are Row-Column designs for the two-way elimination of heterogeneity. The incomplete columns of these Youden-m square designs constitute PBIB designs. With the present functionality, the package will be of immense importance for the researchers as it will help them to construct PBIB designs, to check if their PBIB designs and association scheme satisfy various necessary conditions for the existence, to calculate the efficiencies of PBIB designs based on any association scheme and to construct Youden-m square designs for the two-way elimination of heterogeneity. R. C. Bose and K. R. Nair (1939) <http://www.jstor.org/stable/40383923>.

This package provides a unified framework for generating, submitting, and analyzing pairwise comparisons of writing quality using large language models (LLMs). The package supports live and/or batch evaluation workflows across multiple providers ('OpenAI', Anthropic', Google Gemini', Together AI', and locally-hosted Ollama models), includes bias-tested prompt templates and a flexible template registry, and offers tools for constructing forward and reversed comparison sets to analyze consistency and positional bias. Results can be modeled using Bradleyâ Terry (1952) <doi:10.2307/2334029> or Elo rating methods to derive writing quality scores. For information on the method of pairwise comparisons, see Thurstone (1927) <doi:10.1037/h0070288> and Heldsinger & Humphry (2010) <doi:10.1007/BF03216919>. For information on Elo ratings, see Clark et al. (2018) <doi:10.1371/journal.pone.0190393>.

This package provides functionality to support data preparation and exploration for palaeobiological analyses, improving code reproducibility and accessibility. The wider aim of palaeoverse is to bring the palaeobiological community together to establish agreed standards. The package currently includes functionality for data cleaning, binning (time and space), exploration, summarisation and visualisation. Reference datasets (i.e. Geological Time Scales <https://stratigraphy.org/chart/>) and auxiliary functions are also provided. Details can be found in: Jones et al., (2023) <doi: 10.1111/2041-210X.14099>.

Market odds from from Pinnacle, an online sports betting bookmaker (see <https://www.pinnacle.com> for more information). Included are datasets for the Major League Baseball (MLB) 2016 season and the USA election 2016. These datasets can be used to build models and compare statistical information with the information from prediction markets.The Major League Baseball (MLB) 2016 dataset can be used for sabermetrics analysis and also can be used in conjunction with other popular Major League Baseball (MLB) datasets such as Retrosheets or the Lahman package by merging by GameID.

Interactive shiny application for working with Probability Distributions. Calculations and Graphs are provided.

The main function, plot_mm(), is used for (gg)plotting output from mixture models, including both densities and overlaying mixture weight component curves from the fit models in line with the tidy principles. The package includes several additional functions for added plot customization. Supported model objects include: mixtools', EMCluster', and flexmix', with more from each in active dev. Supported mixture model specifications include mixtures of univariate Gaussians, multivariate Gaussians, Gammas, logistic regressions, linear regressions, and Poisson regressions.