This package provides statistical methods for network meta-analysis of diagnostic tests to simultaneously compare multiple tests within a missing data framework, including: - Bayesian hierarchical model for network meta-analysis of multiple diagnostic tests (Ma, Lian, Chu, Ibrahim, and Chen (2018) <doi:10.1093/biostatistics/kxx025>) - Bayesian Hierarchical Summary Receiver Operating Characteristic Model for Network Meta-Analysis of Diagnostic Tests (Lian, Hodges, and Chu (2019) <doi:10.1080/01621459.2018.1476239>).

Automated population pharmacokinetic modeling framework for data-driven initialisation, model evaluation, and metaheuristic optimization. Supports genetic algorithms, ant colony optimization, tabu search, and stepwise procedures for automated model selection and parameter estimation within the nlmixr2 ecosystem.

Routines for fitting and simulating data under autoregressive fractionally integrated moving average (ARFIMA) models, without the constraint of covariance stationarity. Two fitting methods are implemented, a pseudo-maximum likelihood method and a minimum distance estimator. Mayoral, L. (2007) <doi:10.1111/j.1368-423X.2007.00202.x>. Beran, J. (1995) <doi:10.1111/j.2517-6161.1995.tb02054.x>.

Semissupervised model for geographical document classification (Watanabe 2018) <doi:10.1080/21670811.2017.1293487>. This package currently contains seed dictionaries in English, German, French, Spanish, Italian, Russian, Hebrew, Arabic, Turkish, Japanese and Chinese (Simplified and Traditional).

Constructs (non)additive genetic relationship matrices, and their inverses, from a pedigree to be used in linear mixed effect models (A.K.A. the animal model'). Also includes other functions to facilitate the use of animal models. Some functions have been created to be used in conjunction with the R package asreml for the ASReml software, which can be obtained upon purchase from VSN international (<https://vsni.co.uk/software/asreml>).

This package performs nonparametric estimation in mixture cure models when the cure status is partially known. For details, see Safari et al (2021) <doi:10.1002/bimj.202100156>, Safari et al (2022) <doi:10.1177/09622802221115880> and Safari et al (2023) <doi:10.1007/s10985-023-09591-x>.

Access the United States National Provider Identifier Registry API <https://npiregistry.cms.hhs.gov/api/>. Obtain and transform administrative data linked to a specific individual or organizational healthcare provider, or perform advanced searches based on provider name, location, type of service, credentials, and other attributes exposed by the API.

This package provides a small multilayer perceptron implementation for R'. It supports regression and classification, multiple hidden layers, mini-batch training, Adam, SGD, momentum, Nesterov, RPROP, GRPROP and L-BFGS optimizers, dropout, L2 regularization, early stopping, convergence thresholds, gradient clipping, sample and class weights, callback hooks, target scaling and robust Huber loss for regression, Rcpp forward-pass kernels, formula interfaces, model evaluation with balanced classification metrics, cross-validation, compact tuning, permutation importance, model persistence helpers, and S3 prediction methods. Methods follow Rumelhart, Hinton and Williams (1986) <doi:10.1038/323533a0>, with optimizers including Riedmiller and Braun (1993) <doi:10.1109/ICNN.1993.298623>, Nocedal (1980) <doi:10.1090/S0025-5718-1980-0572855-7>, and Kingma and Ba (2014) <doi:10.48550/arXiv.1412.6980>.

This package creates and detects nonlinear relations using the methods described in Slipetz, Qiu, Sun, and Henry (2026) <doi:10.48550/arXiv.2411.02763>. Use the netgen() function to generate a nonlinear network and the dcor_res() function for a residualization procedure for detecting nonlinear relations.

Assist novice developers when preparing a single package or a set of integrated packages to submit to CRAN. Automate the following individual or batch processing: check local source packages; build local .tar.gz source files; install packages from local .tar.gz files; detect conflicts between function names in the environment.

Various visual and numerical diagnosis methods for the nonlinear mixed effect model, including visual predictive checks, numerical predictive checks, and coverage plots (Karlsson and Holford, 2008, <https://www.page-meeting.org/?abstract=1434>).

This package provides functions to compute the non-negative garrote estimator as proposed by Breiman (1995) <https://www.jstor.org/stable/1269730> with the penalized initial estimators extension as proposed by Yuan and Lin (2007) <https://www.jstor.org/stable/4623260>.

Combines Autoencoders with the STATIS (Structuring Three-way Arrays in Statistics) methodology for dimensional reduction and visualization of multi-way data (tables x individuals x variables). Methods are based on L'Hermier des Plantes (1976) and Carrera Buri & Galindo-Villardón (2026) <https://www.mdpi.com/1999-4893/19/8/637/pdf>.

This package implements the nonparametric causality-in-quantiles test (in mean or variance), returning a test object with an S3 plot() method. The current implementation uses one lag of each series (first-order Granger causality setup). Methodology is based on Balcilar, Gupta, and Pierdzioch (2016a) <doi:10.1016/j.resourpol.2016.04.004> and Balcilar et al. (2016) <doi:10.1007/s11079-016-9388-x>.

This package implements methods in Mathur and VanderWeele (in preparation) to characterize global evidence strength across W correlated ordinary least squares (OLS) hypothesis tests. Specifically, uses resampling to estimate a null interval for the total number of rejections in, for example, 95% of samples generated with no associations (the global null), the excess hits (the difference between the observed number of rejections and the upper limit of the null interval), and a test of the global null based on the number of rejections.

Fits regularization paths for linear regression, GLM, and Cox regression models using lasso or nonconvex penalties, in particular the minimax concave penalty (MCP) and smoothly clipped absolute deviation (SCAD) penalty, with options for additional L2 penalties (the "elastic net" idea). Utilities for carrying out cross-validation as well as post-fitting visualization, summarization, inference, and prediction are also provided. For more information, see Breheny and Huang (2011) <doi:10.1214/10-AOAS388> or visit the ncvreg homepage <https://pbreheny.github.io/ncvreg/>.

Native rasters are a core R image format which use a compact color representation. This color representation closely aligns with graphics device internals meaning that these images can be rendered quickly. This package provides functions to quickly create, manipulate and composite native rasters.

This package provides a unified, programmatic interface for searching, browsing, and retrieving metadata from various international organization data repositories that use the National Data Archive ('NADA') software, such as the World Bank, FAO', and the International Household Survey Network ('IHSN'). Functions allow users to discover available data collections, country codes, and access types, perform complex searches using keyword and spatial/temporal filters, and retrieve detailed study information, including file lists and variable-level data dictionaries. It simplifies access to microdata for researchers and policy analysts globally.

Fit multinomial logistic regression with a penalty on the nuclear norm of the estimated regression coefficient matrix, using proximal gradient descent.

This package provides a fast algorithm for solving non-negative least squares problems. It implements the Fast Non-Negative Least Squares algorithm. of Bro and De Jong (1997)<doi:10.1002/(SICI)1099-128X(199709/10)11:53.0.CO;2-L>.

This data package contains the Item Response Theory (IRT) parameters for the National Center for Education Statistics (NCES) items used on the National Assessment of Education Progress (NAEP) from 1990 to 2015. The values in these tables are used along with NAEP data to turn student item responses into scores and include information about item difficulty, discrimination, and guessing parameter for 3 parameter logit (3PL) items. Parameters for Generalized Partial Credit Model (GPCM) items are also included. The adjustments table contains the information regarding the treatment of items (e.g., deletion of an item or a collapsing of response categories), when these items did not appear to fit the item response models used to describe the NAEP data. Transformation constants change the score estimates that are obtained from the IRT scaling program to the NAEP reporting metric. Values from the years 2000 - 2013 were taken from the NCES website <https://nces.ed.gov/nationsreportcard/> and values from 1990 - 1998 and 2015 were extracted from their NAEP data files. All subtest names were reduced and homogenized to one word (e.g. "Reading to gain information" became "information"). The various subtest names for univariate transformation constants were all homogenized to "univariate".

This package implements the high-dimensional clustering technique Thresholding After Random Projections (n-TARP). Provides functionality to iteratively decompose larger datasets using contextual variables or within-cluster sum of squares. See Tarun & Boutin (2018) <doi:10.48550/arXiv.1806.05297> and Tarun & Boutin (2018) <doi:10.4231/R74B2ZJV> for the original method and applications.

This package provides streamlined installation for packages from the natverse', a suite of R packages for computational neuroanatomy built on top of the nat NeuroAnatomy Toolbox package. Installation of the complete natverse suite requires a GitHub user account and personal access token GITHUB_PAT'. natmanager will help the end user set this up if necessary.

This package provides neutrosophic statistical methods for interval-valued data from completely randomized and randomized complete block designs. Methods include neutrosophic analysis of variance, analysis of covariance, multivariate analysis of variance, pooled analysis of variance, Levene's test, and Aitken transformation. When the lower and upper bounds are equal (crisp data), the methods reduce to their corresponding classical statistical analyses. The basic concept of neutrosophic statistics is based on Smarandache (2014) <https://fs.unm.edu/NeutrosophicStatistics.pdf>, while the statistical analysis procedures implemented in this package are newly developed.