This package provides functions that can be used to calculate time-dependent state and parameter sensitivities for both continuous- and discrete-time deterministic models. See Ng et al. (2023) <doi:10.1086/726143> for more information about time-dependent sensitivity analysis.

The aim of the R package treebalance is to provide functions for the computation of a large variety of (im)balance indices for rooted trees. The package accompanies the book Tree balance indices: a comprehensive survey by M. Fischer, L. Herbst, S. Kersting, L. Kuehn and K. Wicke (2023) <ISBN: 978-3-031-39799-8>, <doi:10.1007/978-3-031-39800-1>, which gives a precise definition for the terms balance index and imbalance index (Chapter 4) and provides an overview of the terminology in this manual (Chapter 2). For further information on (im)balance indices, see also Fischer et al. (2021) <https://treebalance.wordpress.com>. Considering both established and new (im)balance indices, treebalance provides (among others) functions for calculating the following 18 established indices and index families: the average leaf depth, the B1 and B2 index, the Colijn-Plazzotta rank, the normal, corrected, quadratic and equal weights Colless index, the family of Colless-like indices, the family of I-based indices, the Rogers J index, the Furnas rank, the rooted quartet index, the s-shape statistic, the Sackin index, the symmetry nodes index, the total cophenetic index and the variance of leaf depths. Additionally, we include 9 tree shape statistics that satisfy the definition of an (im)balance index but have not been thoroughly analyzed in terms of tree balance in the literature yet. These are: the total internal path length, the total path length, the average vertex depth, the maximum width, the modified maximum difference in widths, the maximum depth, the maximum width over maximum depth, the stairs1 and the stairs2 index. As input, most functions of treebalance require a rooted (phylogenetic) tree in phylo format (as introduced in ape 1.9 in November 2006). phylo is used to store (phylogenetic) trees with no vertices of out-degree one. For further information on the format we kindly refer the reader to E. Paradis (2012) <http://ape-package.ird.fr/misc/FormatTreeR_24Oct2012.pdf>.

Perform a Visual Predictive Check (VPC), while accounting for stratification, censoring, and prediction correction. Using piping from magrittr', the intuitive syntax gives users a flexible and powerful method to generate VPCs using both traditional binning and a new binless approach Jamsen et al. (2018) <doi:10.1002/psp4.12319> with Additive Quantile Regression (AQR) and Locally Estimated Scatterplot Smoothing (LOESS) prediction correction.

This package provides functions and example files to calculate the tRNA adaptation index, a measure of the level of co-adaptation between the set of tRNA genes and the codon usage bias of protein-coding genes in a given genome. The methodology is described in dos Reis, Wernisch and Savva (2003) <doi:10.1093/nar/gkg897>, and dos Reis, Savva and Wernisch (2004) <doi:10.1093/nar/gkh834>.

This is a tidy implementation for heatmap. At the moment it is based on the (great) package ComplexHeatmap'. The goal of this package is to interface a tidy data frame with this powerful tool. Some of the advantages are: Row and/or columns colour annotations are easy to integrate just specifying one parameter (column names). Custom grouping of rows is easy to specify providing a grouped tbl. For example: df %>% group_by(...). Labels size adjusted by row and column total number. Default use of Brewer and Viridis palettes.

This package provides the estimation of a time-dependent covariance matrix of returns with the intended use for portfolio optimization. The package offers methods for determining the optimal number of factors to be used in the covariance estimation, a hypothesis test of time-varying covariance, and user-friendly functions for portfolio optimization and rolling window evaluation. The local PCA method, method for determining the number of factors, and associated hypothesis test are based on Su and Wang (2017) <doi:10.1016/j.jeconom.2016.12.004>. The approach to time-varying portfolio optimization follows Fan et al. (2024) <doi:10.1016/j.jeconom.2022.08.007>. The regularisation applied to the residual covariance matrix adopts the technique introduced by Chen et al. (2019) <doi:10.1016/j.jeconom.2019.04.025>.

Comprehensive functions to calculate sample size and power for clinical trials with two co-primary endpoints. The package supports five endpoint combinations: two continuous endpoints (Sozu et al. 2011 <doi:10.1080/10543406.2011.551329>), two binary endpoints using asymptotic methods (Sozu et al. 2010 <doi:10.1002/sim.3972>) and exact methods (Homma and Yoshida 2025 <doi:10.1177/09622802251368697>), mixed continuous and binary endpoints (Sozu et al. 2012 <doi:10.1002/bimj.201100221>), and mixed count and continuous endpoints (Homma and Yoshida 2024 <doi:10.1002/pst.2337>). All methods appropriately account for correlation between endpoints and provide both sample size and power calculation capabilities.

It performs the smoothing approach provided by penalized least squares for univariate and bivariate time series, as proposed by Guerrero (2007) and Gerrero et al. (2017). This allows to estimate the time series trend by controlling the amount of resulting (joint) smoothness. --- Guerrero, V.M (2007) <DOI:10.1016/j.spl.2007.03.006>. Guerrero, V.M; Islas-Camargo, A. and Ramirez-Ramirez, L.L. (2017) <DOI:10.1080/03610926.2015.1133826>.

Helps the R users to get data from Tushare Pro'<https://tushare.pro>. Tushare Pro is a platform as well as a community with a lot of staffs working in financial area. We support financial data such as stock price, financial report statements and digital coins data.

An implementation of the Thornley transport resistance plant growth model. The package can be used to simulate plant growth as forced by climate system variables. The package provides methods for formatting forcing variables, simulating growth dynamics and calibrating model parameters. For more information see Higgins et al. (2025) TTR.PGM: An R package for modelling the distributions and dynamics of plants using the Thornley transport resistance plant growth model. Methods in Ecology and Evolution. in press.

Streamline the processing of Telraam data, sourced from open data mobility sensors. These tools range from data retrieval (without the need for API knowledge) to data visualization, including data preprocessing.

This package provides a framework to work with decision rules. Rules can be extracted from supported models, augmented with (custom) metrics using validation data, manipulated using standard dataframe operations, reordered and pruned based on a metric, predict on unseen (test) data. Utilities include; Creating a rulelist manually, Exporting a rulelist as a SQL case statement and so on. The package offers two classes; rulelist and ruleset based on dataframe.

Tide analysis and prediction of predominantly semi-diurnal tides with two high waters and two low waters during one lunar day (~24.842 hours, ~1.035 days). The analysis should preferably cover an observation period of at least 19 years. For shorter periods, for example, the nodal cycle can not be taken into account, which particularly affects the height calculation. The main objective of this package is to produce tide tables.

Provide a range of functions with multiple criteria for cutting phylogenetic trees at any evolutionary depth. It enables users to cut trees in any orientation, such as rootwardly (from root to tips) and tipwardly (from tips to its root), or allows users to define a specific time interval of interest. It can also be used to create multiple tree pieces of equal temporal width. Moreover, it allows the assessment of novel temporal rates for various phylogenetic indexes, which can be quickly displayed graphically.

Tautulli (<http://tautulli.com>) is a monitoring application for Plex Media Servers (<https://www.plex.tv>) which collects a lot of data about media items and server usage such as play counts. This package interacts with the Tautulli API of any specified server to get said data into R. The Tautulli API documentation is available at <https://github.com/Tautulli/Tautulli/blob/master/API.md>.

This package provides a standardized workflow to reconstruct spatial configurations of altitude-bounded biogeographic systems over time. For example, tabs can model how island archipelagos expand or contract with changing sea levels or how alpine biomes shift in response to tree line movements. It provides functionality to account for various geophysical processes such as crustal deformation and other tectonic changes, allowing for a more accurate representation of biogeographic system dynamics. For more information see De Groeve et al. (2025) <doi:10.21425/fob.18.151677>.

This package implements rank preserving structural failure time model (RPSFTM), iterative parameter estimation (IPE), inverse probability of censoring weights (IPCW), marginal structural model (MSM), simple two-stage estimation (TSEsimp), and improved two-stage estimation with g-estimation (TSEgest) methods for treatment switching in randomized clinical trials.

Bayesian trophic position models using stan by leveraging brms for stable isotope data. Trophic position models are derived by using equations from Post (2002) <doi:10.1890/0012-9658(2002)083[0703:USITET]2.0.CO;2>, Vander Zanden and Vadeboncoeur (2002) <doi:10.1890/0012-9658(2002)083[2152:FAIOBA]2.0.CO;2>, and Heuvel et al. (2024) <doi:10.1139/cjfas-2024-0028>.

Computes the test statistics for examining the significance of autocorrelation in univariate time series, cross-correlation in bivariate time series, Pearson correlations in multivariate series and test statistics for i.i.d. property of univariate series given in Dalla, Giraitis and Phillips (2022), <https://www.cambridge.org/core/journals/econometric-theory/article/abs/robust-tests-for-white-noise-and-crosscorrelation/4D77C12C52433F4C6735E584C779403A>, <https://elischolar.library.yale.edu/cowles-discussion-paper-series/57/>.

This package implements the Maximum Likelihood estimator for baseline, placebo, and treatment groups (three-group) experiments with non-compliance proposed by Gerber, Green, Kaplan, and Kern (2010).

Uses thresholded partial least squares algorithm to create a regression or classification model. For more information, see Lee, Bradlow, and Kable <doi:10.1016/j.crmeth.2022.100227>.

Forecasting of long memory time series in presence of structural break by using TSF algorithm by Papailias and Dias (2015) <doi:10.1016/j.ijforecast.2015.01.006>.

This package provides functions and Examples in Sample Size Calculation in Clinical Research.

This package provides pipeline audit trails and data diagnostics for tidyverse workflows. The audit trail system captures lightweight metadata snapshots at each step of a pipeline, building a structured audit report without storing the data itself. Also includes diagnostic functions for interactive data analysis.