The statistical analysis of circular data using distributions based on symmetric Nonnegative Trigonometric Sums (NNTS). It includes functions to perform empirical analysis and estimate the parameters of density functions. Fernandez-Duran, J.J. and Gregorio-Dominguez, M.M. (2025), "Multimodal Symmetric Circular Distributions Based on Nonnegative Trigonometric Sums and a Likelihood Ratio Test for Reflective Symmetry", <doi:10.48550/arXiv.2412.19501>.

Supplies higher-order coordinatized data specification and fluid transform operators that include pivot and anti-pivot as special cases. The methodology is describe in Zumel', 2018, "Fluid data reshaping with cdata'", <https://winvector.github.io/FluidData/FluidDataReshapingWithCdata.html> , <DOI:10.5281/zenodo.1173299> . This package introduces the idea of explicit control table specification of data transforms. Works on in-memory data or on remote data using rquery and SQL database interfaces.

Enables simultaneous statistical inference for the accuracy of multiple classifiers in multiple subgroups (strata). For instance, allows to perform multiple comparisons in diagnostic accuracy studies with co-primary endpoints sensitivity and specificity (Westphal M, Zapf A. Statistical inference for diagnostic test accuracy studies with multiple comparisons. Statistical Methods in Medical Research. 2024;0(0). <doi:10.1177/09622802241236933>).

Perform state and parameter inference, and forecasting, in stochastic state-space systems using the ctsmTMB class. This class, built with the R6 package, provides a user-friendly interface for defining and handling state-space models. Inference is based on maximum likelihood estimation, with derivatives efficiently computed through automatic differentiation enabled by the TMB'/'RTMB packages (Kristensen et al., 2016) <doi:10.18637/jss.v070.i05>. The available inference methods include Kalman filters, in addition to a Laplace approximation-based smoothing method. For further details of these methods refer to the documentation of the CTSMR package <https://ctsm.info/ctsmr-reference.pdf> and Thygesen (2025) <doi:10.48550/arXiv.2503.21358>. Forecasting capabilities include moment predictions and stochastic path simulations, both implemented in C++ using Rcpp (Eddelbuettel et al., 2018) <doi:10.1080/00031305.2017.1375990> for computational efficiency.

This package provides a collection of coding functions as alternatives to the standard functions in the stats package, which have names starting with contr.'. Their main advantage is that they provide a consistent method for defining marginal effects in factorial models. In a simple one-way ANOVA model the intercept term is always the simple average of the class means.

This package provides a simple way to write ".Rprofile" code in an R Markdown file and have it knit to the correct location for your operating system.

Provide standard tables, listings, and graphs (TLGs) libraries used in clinical trials. This package implements a structure to reformat the data with dunlin', create reporting tables using rtables and tern with standardized input arguments to enable quick generation of standard outputs. In addition, it also provides comprehensive data checks and script generation functionality.

An interactive document on the topic of classification tree analysis using rmarkdown and shiny packages. Runtime examples are provided in the package function as well as at <https://kartikeyab.shinyapps.io/CTShiny/>.

Implementation of the categorical instrumental variable (CIV) estimator proposed by Wiemann (2023) <arXiv:2311.17021>. CIV allows for optimal instrumental variable estimation in settings with relatively few observations per category. To obtain valid inference in these challenging settings, CIV leverages a regularization assumption that implies existence of a latent categorical variable with fixed finite support achieving the same first stage fit as the observed instrument.

Allows the user to apply nice color gradients to shiny elements. The gradients are extracted from the colorffy website. See <https://www.colorffy.com/gradients/catalog>.

Offers a diverse collection of datasets focused on cardiovascular and heart disease research, including heart failure, myocardial infarction, aortic dissection, transplant outcomes, cardiovascular risk factors, drug efficacy, and mortality trends. Designed for researchers, clinicians, epidemiologists, and data scientists, the package features clinical, epidemiological, and simulated datasets covering a wide range of conditions and treatments such as statins, anticoagulants, and beta blockers. It supports analyses related to disease progression, treatment effects, rehospitalization, and public health outcomes across various cardiovascular patient populations.

Estimate the direct and indirect (mediation) effects of treatment on the outcome when intermediate variables (mediators) are compositional and high-dimensional. Sohn, M.B. and Li, H. (2017). Compositional Mediation Analysis for Microbiome Studies. (AOAS: In revision).

Calculate the distance between single-arm observational studies using covariate information to remove heterogeneity in Network Meta-Analysis (NMA) of randomized clinical trials. Facilitate the inclusion of observational data in NMA, enhancing the comprehensiveness and robustness of comparative effectiveness research. Schmitz (2018) <doi:10.1186/s12874-018-0509-7>.

Use frequentist and Bayesian methods to estimate parameters from a binary outcome misclassification model. These methods correct for the problem of "label switching" by assuming that the sum of outcome sensitivity and specificity is at least 1. A description of the analysis methods is available in Hochstedler and Wells (2023) <doi:10.48550/arXiv.2303.10215>.

Augment clinical data with metadata to create output used in conventional publications and reports.

This package provides a function that facilitates fitting three types of models for contrast-based Bayesian Network Meta Analysis. The first model is that which is described in Lu and Ades (2006) <doi:10.1198/016214505000001302>. The other two models are based on a Bayesian nonparametric methods that permit ties when comparing treatment or for a treatment effect to be exactly equal to zero. In addition to the model fits, the package provides a summary of the interplay between treatment effects based on the procedure described in Barrientos, Page, and Lin (2023) <doi:10.48550/arXiv.2207.06561>.

Inference with control function methods for nonlinear outcome models when the model is known ('Guo and Small (2016) <arXiv:1602.01051>) and when unknown but semiparametric ('Li and Guo (2021) <arXiv:2010.09922>).

This package provides functions for nonlinear regression parameters estimation by algorithms based on Controlled Random Search algorithm. Both functions (crs4hc(), crs4hce()) adapt current search strategy by four heuristics competition. In addition, crs4hce() improves adaptability by adaptive stopping condition.

Calculates metrics of proportionality using the logit-normal multinomial model. It can also provide empirical and plugin estimates of these metrics.

Create Pairwise Comparison Matrices for use in the Analytic Hierarchy Process. The Pairwise Comparison Matrix created will be a logical matrix, which unlike a random comparison matrix, is similar to what a rational decision maker would create on the basis of a preference vector for the alternatives considered.

Statistical tests for the comparison between two correlations based on either independent or dependent groups. Dependent correlations can either be overlapping or nonoverlapping. A web interface is available on the website <http://comparingcorrelations.org>. A plugin for the R GUI and IDE RKWard is included. Please install RKWard from <https://rkward.kde.org> to use this feature. The respective R package rkward cannot be installed directly from a repository, as it is a part of RKWard.

This package provides a lightweight data validation and testing toolkit for R. Its guiding philosophy is that adding code-based data checks to users existing workflow should be both quick and intuitive. The suite of functions included therefore mirror the common data checks many users already perform by hand or by eye. Additionally, the checkthat package is optimized to work within tidyverse data manipulation pipelines.

This package provides object-oriented database management tools for working with large datasets across multiple database systems. Features include robust connection management for SQL Server and PostgreSQL databases, advanced table operations with bulk data loading and upsert functionality, comprehensive data validation through customizable field type and content validators, efficient index management, and cross-database compatibility. Designed for high-performance data operations in surveillance systems and large-scale data processing workflows.

This package provides a reliable and efficient tool for cleaning univariate time series data. It implements reliable and efficient procedures for automating the process of cleaning univariate time series data. The package provides integration with already developed and deployed tools for missing value imputation and outlier detection. It also provides a way of visualizing large time-series data in different resolutions.