Adds an LLM-powered chatbot to your shiny app, that can turn your users natural language questions into SQL queries that run against your data, and return the result as a reactive data frame. Use it to drive reactive calculations, visualizations, downloads, and more.

This function aims to calculate risk of developing cardiovascular disease of individual patients in next 10 years. This unofficial package was based on published open-sourced free risk prediction algorithm QRISK3-2017 <https://qrisk.org/src.php>.

Design of QTL (quantitative trait locus) experiments involves choosing which strains to cross, the type of cross, genotyping strategies, phenotyping strategies, and the number of progeny to raise and phenotype. This package provides tools to help make such choices. Sen and others (2007) <doi:10.1007/s00335-006-0090-y>.

This package provides different functions for quantifying qualitative survey data. It supports the Carlson-Parkin method, the regression approach, the balance approach and the conditional expectations method.

Grows a qualitative interaction tree. Quint is a tool for subgroup analysis, suitable for data from a two-arm randomized controlled trial. More information in Dusseldorp, E., Doove, L., & Van Mechelen, I. (2016) <doi:10.3758/s13428-015-0594-z>.

Helper functions for Qualitative Comparative Analysis: evaluate and plot Boolean formulae on fuzzy set score data, apply Boolean operations, compute consistency and coverage measures.

Primarily, the qcv package computes key indices related to the Quantifying Construct Validity procedure (QCV; Westen & Rosenthal, 2003 <doi:10.1037/0022-3514.84.3.608>; see also Furr & Heuckeroth, in press). The qcv() function is the heart of the qcv package, but additional functions in the package provide useful ancillary information related to the QCV procedure.

This package provides tools for (automated and manual) quality control of the results of Epigenome-Wide Association Studies.

This package provides an infrastructure for efficient processing of large-scale genetic and phenotypic data including core functions for: 1) fitting linear mixed models, 2) constructing marker-based genomic relationship matrices, 3) estimating genetic parameters (heritability and correlation), 4) performing genomic prediction and genetic risk profiling, and 5) single or multi-marker association analyses. Rohde et al. (2019) <doi:10.1101/503631>.

This package provides a re-implementation of quantile kriging. Quantile kriging was described by Plumlee and Tuo (2014) <doi:10.1080/00401706.2013.860919>. With computational savings when dealing with replication from the recent paper by Binois, Gramacy, and Ludovski (2018) <doi:10.1080/10618600.2018.1458625> it is now possible to apply quantile kriging to a wider class of problems. In addition to fitting the model, other useful tools are provided such as the ability to automatically perform leave-one-out cross validation.

This package provides a sigmoidal quantile function estimator based on a newly defined generalized expectile function. The generalized sigmoidal quantile function can estimate quantiles beyond the range of the data, which is important for certain applications given smaller sample sizes. The package is based on the method introduced in Hutson (2024) <doi:10.1080/03610918.2022.2032161>.

Uses the fst package to store genotype probabilities on disk for the qtl2 package. These genotype probabilities are a central data object for mapping quantitative trait loci (QTL), but they can be quite large. The facilities in this package enable the genotype probabilities to be stored on disk, leading to reduced memory usage with only a modest increase in computation time.

Resources, tutorials, and code snippets dedicated to exploring the intersection of quantum computing and artificial intelligence (AI) in the context of analyzing Cluster of Differentiation 4 (CD4) lymphocytes and optimizing antiretroviral therapy (ART) for human immunodeficiency virus (HIV). With the emergence of quantum artificial intelligence and the development of small-scale quantum computers, there's an unprecedented opportunity to revolutionize the understanding of HIV dynamics and treatment strategies. This project leverages the R package qsimulatR (Ostmeyer and Urbach, 2023, <https://CRAN.R-project.org/package=qsimulatR>), a quantum computer simulator, to explore these applications in quantum computing techniques, addressing the challenges in studying CD4 lymphocytes and enhancing ART efficacy.

This package provides a collection of routines for finding reference limits using, where appropriate, QQ methodology. All use a data vector X of cases from the reference population. The default is to get the central 95% reference range of the population, namely the 2.5 and 97.5 percentile, with optional adjustment of the range. Along with the reference limits, we want confidence intervals which, for historical reasons, are typically at 90% confidence. A full analysis provides six numbers: â the upper and the lower reference limits, and - each of their confidence intervals. For application details, see Hawkins and Esquivel (2024) <doi:10.1093/jalm/jfad109>.

Simulating and estimating peer effect models including the quantile-based specification (Houndetoungan, 2025 <doi:10.48550/arXiv.2506.12920>), and the models with Constant Elasticity of Substitution (CES)-based social norm (Boucher et al., 2024 <doi:10.3982/ECTA21048>).

Various quantile-based clustering algorithms: algorithm CU (Common theta and Unscaled variables), algorithm CS (Common theta and Scaled variables through lambda_j), algorithm VU (Variable-wise theta_j and Unscaled variables) and algorithm VW (Variable-wise theta_j and Scaled variables through lambda_j). Hennig, C., Viroli, C., Anderlucci, L. (2019) "Quantile-based clustering." Electronic Journal of Statistics. 13 (2) 4849 - 4883 <doi:10.1214/19-EJS1640>.

This package provides a tool for automatic generation of sibling items from a parent item model defined by the user. It is an implementation of the process automatic item generation (AIG) focused on generating quantitative multiple-choice type of items (see Embretson, Kingston (2018) <doi:10.1111/jedm.12166>).

Developed to perform the estimation and inference for regression coefficient parameters in longitudinal marginal models using the method of quadratic inference functions. Like generalized estimating equations, this method is also a quasi-likelihood inference method. It has been showed that the method gives consistent estimators of the regression coefficients even if the correlation structure is misspecified, and it is more efficient than GEE when the correlation structure is misspecified. Based on Qu, A., Lindsay, B.G. and Li, B. (2000) <doi:10.1093/biomet/87.4.823>.

Create surface forms from matrix or raster data for flexible plotting and conversion to other mesh types. The functions quadmesh or triangmesh produce a continuous surface as a mesh3d object as used by the rgl package. This is used for plotting raster data in 3D (optionally with texture), and allows the application of a map projection without data loss and many processing applications that are restricted by inflexible regular grid rasters. There are discrete forms of these continuous surfaces available with dquadmesh and dtriangmesh functions.

Calculates the number of four-taxon subtrees consistent with a pair of cladograms, calculating the symmetric quartet distance of Bandelt & Dress (1986), Reconstructing the shape of a tree from observed dissimilarity data, Advances in Applied Mathematics, 7, 309-343 <doi:10.1016/0196-8858(86)90038-2>, and using the tqDist algorithm of Sand et al. (2014), tqDist: a library for computing the quartet and triplet distances between binary or general trees, Bioinformatics, 30, 2079â 2080 <doi:10.1093/bioinformatics/btu157> for pairs of binary trees.

This package provides functions are provided that implement the use of the Fieller's formula methodology, for calculating a confidence interval for a ratio of (commonly, correlated) means. See Fieller (1954) <doi:10.1111/j.2517-6161.1954.tb00159.x>. Here, the application of primary interest is to studies of insect mortality response to increasing doses of a fumigant, or, e.g., to time in coolstorage. The formula is used to calculate a confidence interval for the dose or time required to achieve a specified mortality proportion, commonly 0.5 or 0.99. Vignettes demonstrate link functions that may be considered, checks on fitted models, and alternative choices of error family. Note in particular the betabinomial error family. See also Maindonald, Waddell, and Petry (2001) <doi:10.1016/S0925-5214(01)00082-5>.

Helps to perform linear regression analysis by reducing manual effort. Reduces the independent variables based on specified p-value and Variance Inflation Factor (VIF) level.

This package provides functions to plot QTL (quantitative trait loci) analysis results and related diagnostics. Part of qtl2', an upgrade of the qtl package to better handle high-dimensional data and complex cross designs.

This package produces quality scores for each of the US companies from the Russell 3000, following the approach described in "Quality Minus Junk" (Asness, Frazzini, & Pedersen, 2013) <http://www.aqr.com/library/working-papers/quality-minus-junk>. The package includes datasets for users who wish to view the most recently uploaded quality scores. It also provides tools to automatically gather relevant financials and stock price information, allowing users to update their data and customize their universe for further analysis.