This package provides functions to read and write APE-compatible phylogenetic trees in NEXUS and Newick formats, while preserving annotations.

Generate nicely formatted HTML tables to display estimation results for pharmacometric models.

Supports propensity score weighting analysis of observational studies and randomized trials. Enables the estimation and inference of average causal effects with binary and multiple treatments using overlap weights (ATO), inverse probability of treatment weights (ATE), average treatment effect among the treated weights (ATT), matching weights (ATM) and entropy weights (ATEN), with and without propensity score trimming. These weights are members of the family of balancing weights introduced in Li, Morgan and Zaslavsky (2018) <doi:10.1080/01621459.2016.1260466> and Li and Li (2019) <doi:10.1214/19-AOAS1282>.

Clustering analysis for sparse microbiome data, based on a Poisson hurdle model.

This toolkit is designed for manipulation and analysis of peptides. It provides functionalities to assist researchers in peptide engineering and proteomics. Users can manipulate peptides by adding amino acids at every position, count occurrences of each amino acid at each position, and transform amino acid counts based on probabilities. The package offers functionalities to select the best versus the worst peptides and analyze these peptides, which includes counting specific residues, reducing peptide sequences, extracting features through One Hot Encoding (OHE), and utilizing Quantitative Structure-Activity Relationship (QSAR) properties (based in the package Peptides by Osorio et al. (2015) <doi:10.32614/RJ-2015-001>). This package is intended for both researchers and bioinformatics enthusiasts working on peptide-based projects, especially for their use with machine learning.

This package provides a doubly robust precision medicine approach to fit, cross-validate and visualize prediction models for the conditional average treatment effect (CATE). It implements doubly robust estimation and semiparametric modeling approach of treatment-covariate interactions as proposed by Yadlowsky et al. (2020) <doi:10.1080/01621459.2020.1772080>.

This package provides methods for reducing the number of features within a data set. See Bauer JO (2021) <doi:10.1145/3475827.3475832> and Bauer JO, Drabant B (2021) <doi:10.1016/j.jmva.2021.104754> for more information on principal loading analysis.

This package provides a PEP, or Portable Encapsulated Project, is a dataset that subscribes to the PEP structure for organizing metadata. It is written using a simple YAML + CSV format, it is your one-stop solution to metadata management across data analysis environments. This package reads this standardized project configuration structure into R. Described in Sheffield et al. (2021) <doi:10.1093/gigascience/giab077>.

Create and customize interactive phylogenetic trees using the phylocanvas JavaScript library and the htmlwidgets package. These trees can be used directly from the R console, from RStudio', in Shiny apps, and in R Markdown documents. See <http://phylocanvas.org/> for more information on the phylocanvas library.

This package provides functions and data sets for the text Probability and Statistics with R.

The main attribute of PopVar is the prediction of genetic variance in bi-parental populations, from which the package derives its name. PopVar contains a set of functions that use phenotypic and genotypic data from a set of candidate parents to 1) predict the mean, genetic variance, and superior progeny value of all, or a defined set of pairwise bi-parental crosses, and 2) perform cross-validation to estimate genome-wide prediction accuracy of multiple statistical models. More details are available in Mohammadi, Tiede, and Smith (2015, <doi:10.2135/cropsci2015.01.0030>). A dataset think_barley.rda is included for reference and examples.

This package provides advanced algorithms for analyzing pointcloud data from terrestrial laser scanner in forestry applications. Key features include fast voxelization of large datasets; segmentation of point clouds into forest floor, understorey, canopy, and wood components. The package enables efficient processing of large-scale forest pointcloud data, offering insights into forest structure, connectivity, and fire risk assessment. Algorithms to analyze pointcloud data (.xyz input file). For more details, see Ferrara & Arrizza (2025) <https://hdl.handle.net/20.500.14243/533471>. For single tree segmentation details, see Ferrara et al. (2018) <doi:10.1016/j.agrformet.2018.04.008>.

Model-implied simulation-based power estimation (MSPE) for nonlinear (and linear) SEM, path analysis and regression analysis. A theoretical framework is used to approximate the relation between power and sample size for given type I error rates and effect sizes. The package offers an adaptive search algorithm to find the optimal N for given effect sizes and type I error rates. Plots can be used to visualize the power relation to N for different parameters of interest (POI). Theoretical justifications are given in Irmer et al. (2024a) <doi:10.31219/osf.io/pe5bj> and detailed description are given in Irmer et al. (2024b) <doi:10.3758/s13428-024-02476-3>.

The calculation of p-variation of the finite sample data. This package is a realisation of the procedure described in Butkus, V. & Norvaisa, R. Lith Math J (2018). <doi: 10.1007/s10986-018-9414-3> The formal definitions and reference into literature are given in vignette.

Estimate sample size based on precision rather than power. precisely is a study planning tool to calculate sample size based on precision. Power calculations are focused on whether or not an estimate will be statistically significant; calculations of precision are based on the same principles as power calculation but turn the focus to the width of the confidence interval. precisely is based on the work of Rothman and Greenland (2018).

Computes the All-Resolution Inference method in the permutation framework, i.e., simultaneous lower confidence bounds for the number of true discoveries. <doi:10.1002/sim.9725>.

This package provides functions to simulate Pool-seq data under models of demographic formation and to import Pool-seq data from real populations. Implements two ABC algorithms for performing parameter estimation and model selection using Pool-seq data. Cross-validation can also be performed to assess the accuracy of ABC estimates and model choice. Carvalho et al., (2022) <doi:10.1111/1755-0998.13834>.

Using the Bayesian state-space approach, we developed a continuous development model to quantify dynamic incremental changes in the response variable. While the model was originally developed for daily changes in forest green-up, the model can be used to predict any similar process. The CDM can capture both timing and rate of nonlinear processes. Unlike statics methods, which aggregate variations into a single metric, our dynamic model tracks the changing impacts over time. The CDM accommodates nonlinear responses to variation in predictors, which changes throughout development.

This package provides a framework for defining pipelines of functions for applying data transformations, model estimation and inverse-transformations, resulting in predicted value generation (or model-scoring) functions that automatically apply the entire pipeline of functions required to go from input to predicted output.

Phylogenetic comparative methods represent models of continuous trait data associated with the tips of a phylogenetic tree. Examples of such models are Gaussian continuous time branching stochastic processes such as Brownian motion (BM) and Ornstein-Uhlenbeck (OU) processes, which regard the data at the tips of the tree as an observed (final) state of a Markov process starting from an initial state at the root and evolving along the branches of the tree. The PCMBase R package provides a general framework for manipulating such models. This framework consists of an application programming interface for specifying data and model parameters, and efficient algorithms for simulating trait evolution under a model and calculating the likelihood of model parameters for an assumed model and trait data. The package implements a growing collection of models, which currently includes BM, OU, BM/OU with jumps, two-speed OU as well as mixed Gaussian models, in which different types of the above models can be associated with different branches of the tree. The PCMBase package is limited to trait-simulation and likelihood calculation of (mixed) Gaussian phylogenetic models. The PCMFit package provides functionality for inference of these models to tree and trait data. The package web-site <https://venelin.github.io/PCMBase/> provides access to the documentation and other resources.

This package provides an implementation of particle swarm optimisation consistent with the standard PSO 2007/2011 by Maurice Clerc. Additionally a number of ancillary routines are provided for easy testing and graphics.

Calculates the periodogram of a time series, maximum-likelihood fits an Ornstein-Uhlenbeck state space (OUSS) null model and evaluates the statistical significance of periodogram peaks against the OUSS null hypothesis. The OUSS is a parsimonious model for stochastically fluctuating variables with linear stabilizing forces, subject to uncorrelated measurement errors. Contrary to the classical white noise null model for detecting cyclicity, the OUSS model can account for temporal correlations typically occurring in ecological and geological time series. Citation: Louca, Stilianos and Doebeli, Michael (2015) <doi:10.1890/14-0126.1>.

Based on different statistical definitions of discrimination, several methods have been proposed to detect and mitigate social inequality in machine learning models. This package aims to provide an alternative to fairness treatment in predictive models. The ROC method implemented in this package is described by Kamiran, Karim and Zhang (2012) <https://ieeexplore.ieee.org/document/6413831/>.

Fits and analyses time dependent marked point process models with an emphasis on earthquake modelling. For a more detailed introduction to the package, see the topic "PtProcess". A list of recent changes can be found in the topic "Change Log".