ANOVA and REML estimation of linear mixed models is implemented, once following Searle et al. (1991, ANOVA for unbalanced data), once making use of the lme4 package. The primary objective of this package is to perform a variance component analysis (VCA) according to CLSI EP05-A3 guideline "Evaluation of Precision of Quantitative Measurement Procedures" (2014). There are plotting methods for visualization of an experimental design, plotting random effects and residuals. For ANOVA type estimation two methods for computing ANOVA mean squares are implemented (SWEEP and quadratic forms). The covariance matrix of variance components can be derived, which is used in estimating confidence intervals. Linear hypotheses of fixed effects and LS means can be computed. LS means can be computed at specific values of covariables and with custom weighting schemes for factor variables. See ?VCA for a more comprehensive description of the features.

Implementation of the variable banding procedure for modeling local dependence and estimating precision matrices that is introduced in Yu & Bien (2016) and is available at <https://arxiv.org/abs/1604.07451>.

This package produces violin plots with optional nonparametric (Mann-Whitney test) and parametric (Tukey's honest significant difference) mean comparison and linear regression. This package aims to be a simple and quick visualization tool for comparing means and assessing trends of categorical factors.

Describe in words the genealogical relationship between two members of a given pedigree, using the algorithm in Vigeland (2022) <doi:10.1186/s12859-022-04759-y>. verbalisr is part of the pedsuite collection of packages for pedigree analysis. For a demonstration of verbalisr', see the online app QuickPed at <https://magnusdv.shinyapps.io/quickped>.

Automatically selects and visualises statistical hypothesis tests between two vectors, based on their class, distribution, sample size, and a user-defined confidence level (conf.level). Visual outputs - including box plots, bar charts, regression lines with confidence bands, mosaic plots, residual plots, and Q-Q plots - are annotated with relevant test statistics, assumption checks, and post-hoc analyses where applicable. The algorithmic workflow helps the user focus on the interpretation of test results rather than test selection. It is particularly suited for quick data analysis, e.g., in statistical consulting projects or educational settings. The test selection algorithm proceeds as follows: Input vectors of class numeric or integer are considered numerical; those of class factor are considered categorical. Assumptions of residual normality and homogeneity of variances are considered met if the corresponding test yields a p-value greater than the significance level alpha = 1 - conf.level. (1) When the response vector is numerical and the predictor vector is categorical, a test of central tendencies is selected. If the categorical predictor has exactly two levels, t.test() is applied when group sizes exceed 30 (Lumley et al. (2002) <doi:10.1146/annurev.publhealth.23.100901.140546>). For smaller samples, normality of residuals is tested using shapiro.test(); if met, t.test() is used; otherwise, wilcox.test(). If the predictor is categorical with more than two levels, an aov() is initially fitted. Residual normality is evaluated using both shapiro.test() and ad.test(); residuals are considered approximately normal if at least one test yields a p-value above alpha. If this assumption is met, bartlett.test() assesses variance homogeneity. If variances are homogeneous, aov() is used; otherwise oneway.test(). Both tests are followed by TukeyHSD(). If residual normality cannot be assumed, kruskal.test() is followed by pairwise.wilcox.test(). (2) When both the response and predictor vectors are numerical, a simple linear regression model is fitted using lm(). (3) When both vectors are categorical, Cochran's rule (Cochran (1954) <doi:10.2307/3001666>) is applied to test independence either by chisq.test() or fisher.test().

Craft polished tables and plots in Markdown reports. Simply choose whether to treat your data as counts or metrics, and the package will automatically generate well-designed default tables and plots for you. Boiled down to the basics, with labeling features and simple interactive reports. All functions are tidyverse compatible.

This package provides a variety of tools to allow the quantification of videos of the lymphatic vasculature taken under an operating microscope. Lymphatic vessels that have been injected with a variety of blue dyes can be tracked throughout the video to determine their width over time. Code is optimised for efficient processing of multiple large video files. Functions to calculate physiologically relevant parameters and generate graphs from these values are also included.

Position adjustments for ggplot2 to implement "visualize as you randomize" principles, which can be especially useful when plotting experimental data.

The variable importance is calculated using knock off variables. Then output can be provided in numerical and graphical form. Meredith L Wallace (2023) <doi:10.1186/s12874-023-01965-x>.

This package provides a Variational Bayesian algorithm for high-dimensional multi-source heterogeneous linear models. More details have been written up in a paper submitted to the journal Statistics in Medicine, and the details of variational Bayesian methods can be found in Ray and Szabo (2021) <doi:10.1080/01621459.2020.1847121>. It simultaneously performs parameter estimation and variable selection. The algorithm supports two model settings: (1) local models, where variable selection is only applied to homogeneous coefficients, and (2) global models, where variable selection is also performed on heterogeneous coefficients. Two forms of Spike-and-Slab priors are available: the Laplace distribution and the Gaussian distribution as the Slab component.

This package provides a binding for the valection program which offers various ways to sample the outputs of competing algorithms or parameterizations, and fairly assess their performance against each other. The valection C library is required to use this package and can be downloaded from: <http://labs.oicr.on.ca/boutros-lab/software/valection>. Cooper CI, et al; Valection: Design Optimization for Validation and Verification Studies; Biorxiv 2018; <doi:10.1101/254839>.

The goal of vetiver is to provide fluent tooling to version, share, deploy, and monitor a trained model. Functions handle both recording and checking the model's input data prototype, and predicting from a remote API endpoint. The vetiver package is extensible, with generics that can support many kinds of models.

This package implements a set of routines to perform structured matrix factorization with minimum volume constraints. The NMF procedure decomposes a matrix X into a product C * D. Given conditions such that the matrix C is non-negative and has sufficiently spread columns, then volume minimization of a matrix D delivers a correct and unique, up to a scale and permutation, solution (C, D). This package provides both an implementation of volume-regularized NMF and "anchor-free" NMF, whereby the standard NMF problem is reformulated in the covariance domain. This algorithm was applied in Vladimir B. Seplyarskiy Ruslan A. Soldatov, et al. "Population sequencing data reveal a compendium of mutational processes in the human germ line". Science, 12 Aug 2021. <doi:10.1126/science.aba7408>. This package interacts with data available through the simulatedNMF package, which is available in a drat repository. To access this data package, see the instructions at <https://github.com/kharchenkolab/vrnmf>. The size of the simulatedNMF package is approximately 8 MB.

This package provides fast sampling from von Mises-Fisher distribution using the method proposed by Andrew T.A Wood (1994) <doi:10.1080/03610919408813161>.

The base tools union() intersect(), etc., follow the algebraic definition that each element of a set must be unique. Since it's often helpful to compare all elements of two vectors, this toolset treats every element as unique for counting purposes. For ease of use, all functions in vecsets have an argument multiple which, when set to FALSE, reverts them to the base::sets (alias for all the items) tools functionality.

Allows registered VectorSurv <https://vectorsurv.org/> users access to data through the VectorSurv API <https://api.vectorsurv.org/>. Additionally provides functions for analysis and visualization.

This package performs 18 omnibus tests yielding a total of 28 distinct methodological variations for testing the composite hypothesis of variance homogeneity.

This package creates visualization plots for 2D data including ellipse plots, Voronoi tesselation plots, and combined ellipse-Voronoi plots. Designed to visualize class separation in 2D data, raw of from projection techniques like principal component analysis (PCA), partial least squares discriminant analysis (PLS-DA) or others. For more details see Lotsch and Kringel (2026) and Lotsch, J., and Kringel, D. (2026) <doi:10.1371/journal.pone.0333653>.

Various methods to count ballots in voting systems are provided. Functions to check validity of ballots are also provided to ensure flexibility.

R data pipelines commonly require reading and writing data to versioned directories. Each directory might correspond to one step of a multi-step process, where that version corresponds to particular settings for that step and a chain of previous steps that each have their own versions. This package creates a configuration object that makes it easy to read and write versioned data, based on YAML configuration files loaded and saved to each versioned folder.

Designed to help the user to determine the sensitivity of an proposed causal effect to unconsidered common causes. Users can create visualizations of sensitivity, effect sizes, and determine which pattern of effects would support a causal claim for between group differences. Number needed to treat formula from Kraemer H.C. & Kupfer D.J. (2006) <doi:10.1016/j.biopsych.2005.09.014>.

Alternative splicing produces a variety of different protein products from a given gene. VALERIE enables visualisation of alternative splicing events from high-throughput single-cell RNA-sequencing experiments. VALERIE computes percent spliced-in (PSI) values for user-specified genomic coordinates corresponding to alternative splicing events. PSI is the proportion of sequencing reads supporting the included exon/intron as defined by Shiozawa (2018) <doi:10.1038/s41467-018-06063-x>. PSI are inferred from sequencing reads data based on specialised infrastructures for representing and computing annotated genomic ranges by Lawrence (2013) <doi:10.1371/journal.pcbi.1003118>. Computed PSI for each single cell are subsequently presented in the form of a heatmap implemented using the pheatmap package by Kolde (2010) <https://CRAN.R-project.org/package=pheatmap>. Board overview of the mean PSI difference and associated p-values across different user-defined groups of single cells are presented in the form of a line graph using the ggplot2 package by Wickham (2007) <https://CRAN.R-project.org/package=ggplot2>.

This package provides methods for calculating the variance scale exponent to identify memory patterns in time series data. Includes tests for white noise, short memory, and long memory. See Fu, H. et al. (2018) <doi:10.1016/j.physa.2018.06.092>.

Conducts linear regression using variational Bayesian inference, particularly optimized for genome-wide association mapping and whole-genome prediction which use a number of DNA markers as the explanatory variables. Provides seven regression models which select the important variables (i.e., the variables related to response variables) among the given explanatory variables in different ways (i.e., model structures).