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This package performs two-sample comparisons using the restricted mean survival time (RMST) as a summary measure of the survival time distribution. Three kinds of between-group contrast metrics (i.e., the difference in RMST, the ratio of RMST and the ratio of the restricted mean time lost (RMTL)) are computed. It performs an ANCOVA-type covariate adjustment as well as unadjusted analyses for those measures.
This package provides a unified workflow for building, fitting using external engines, and evaluating ordinary differential equation (ODE)-based pharmacokinetic/pharmacodynamic (PK/PD) models. Supports generation of estimation scenarios and control files for external engines (e.g., Monolix'), simulation of models using rxode2', and creation of goodness-of-fit diagnostics. Includes tools for covariate modeling, virtual population design, and local and global sensitivity analyses.
Penalized spatial median regression using LASSO. The iteratively reweighted least squares algorithm is used to solve the spatial median regression problem and weighted LASSO is employed.
This package provides R bindings for the Stencila Schema <https://schema.stenci.la>. This package is primarily aimed at R developers wanting to programmatically generate, or modify, executable documents.
This package provides functions for the collection of 3D points and curves using a stereo camera setup.
This package provides an integrated suite of tools for handling single nucleotide polymorphism (SNP) genotype data in large-scale genetic studies. Supports importing and merging genotype files, performing quality control on SNP markers and samples, and preparing data for downstream analyses using popular software such as FImpute and PLINK'. Offers S4 classes and methods to efficiently encapsulate SNP data, along with utilities for generating genotype summary statistics and visualization. Additional functionalities include anticlustering approaches for batch effect control, automated script generation for external software, and streamlined workflows for large datasets commonly encountered in animal and plant breeding programs. Designed to facilitate reproducible and scalable SNP data analyses in quantitative and statistical genetics.
Wrapping and supplementing commonly used functions in the R ecosystem related to spatial data science, while serving as a basis for other packages maintained by Wenbo Lv.
Data in multidimensional systems is obtained from operational systems and is transformed to adapt it to the new structure. Frequently, the operations to be performed aim to transform a flat table into a star schema. Transformations can be carried out using professional extract, transform and load tools or tools intended for data transformation for end users. With the tools mentioned, this transformation can be carried out, but it requires a lot of work. The main objective of this package is to define transformations that allow obtaining stars from flat tables easily. In addition, it includes basic data cleaning, dimension enrichment, incremental data refresh and query operations, adapted to this context.
This package provides a consistently well behaved method of interpolation based on piecewise rational functions using Stineman's algorithm.
Mixed-effect proportional hazards models for multistage stratified, cluster-sampled, unequally weighted survey samples. Provides variance estimation by Taylor series linearisation or replicate weights.
This package performs inference for a class of measures to compare competing risk prediction models with censored survival data. The class includes the integrated discrimination improvement index (IDI) and category-less net reclassification index (NRI).
This package provides a comprehensive suite of functions for interfacing with the Survey Solutions APIs (<https://demo.mysurvey.solutions/apidocs/index.html> and <https://docs.mysurvey.solutions/>). It supports all the current POST, GET, and PATCH requests of the REST API and extends its capabilities by integrating selected GraphQL API queries and mutations when REST API equivalents are not available. Designed for ease of use, it includes several convenience functions to streamline operations. The package ensures that data retrieved from the API is automatically transformed into a single, easy-to-use data frame or data table, optimizing it for subsequent analysis and processing. Additionally, it is specifically designed to facilitate seamless integration into shiny applications, enhancing the interactive web application development experience. Built on the robust httr2 package, this version supersedes the previous httr'-based implementation. Recognizing the needs of large-scale data operations such as censuses, the package also incorporates features for parallel processing, enhancing its efficiency and scalability.
This package performs a sentiment analysis of textual contents in R. This implementation utilizes various existing dictionaries, such as Harvard IV, or finance-specific dictionaries. Furthermore, it can also create customized dictionaries. The latter uses LASSO regularization as a statistical approach to select relevant terms based on an exogenous response variable.
Set of functions that access information about deputies and votings in Polish diet from webpage <http://www.sejm.gov.pl>. The package was developed as a result of an internship in MI2 Group - <http://mi2.mini.pw.edu.pl>, Faculty of Mathematics and Information Science, Warsaw University of Technology.
This package provides a pipeline to perform small area estimation and prevalence mapping of binary indicators using health and demographic survey data, described in Dong et al. (2026) <doi:10.1093/jssam/smaf048>, Wakefield et al. (2025) <doi:10.48550/arXiv.2110.09576> and Wakefield et al. (2020) <doi:10.1111/insr.12400>.
This package performs parametric and non-parametric estimation and simulation for multi-state discrete-time semi-Markov processes. For the parametric estimation, several discrete distributions are considered for the sojourn times: Uniform, Geometric, Poisson, Discrete Weibull and Negative Binomial. The non-parametric estimation concerns the sojourn time distributions, where no assumptions are done on the shape of distributions. Moreover, the estimation can be done on the basis of one or several sample paths, with or without censoring at the beginning or/and at the end of the sample paths. Reliability indicators such as reliability, maintainability, availability, BMP-failure rate, RG-failure rate, mean time to failure and mean time to repair are available as well. The implemented methods are described in Barbu, V.S., Limnios, N. (2008) <doi:10.1007/978-0-387-73173-5>, Barbu, V.S., Limnios, N. (2008) <doi:10.1080/10485250701261913> and Trevezas, S., Limnios, N. (2011) <doi:10.1080/10485252.2011.555543>. Estimation and simulation of discrete-time k-th order Markov chains are also considered.
S4 class object for creating and managing group sequential designs. It calculates the efficacy and futility boundaries at each look. It allows modifying the design and tracking the design update history.
Offers Bayesian semiparametric density estimation and tail-index estimation for heavy tailed data, by using a parametric, tail-respecting transformation of the data to the unit interval and then modeling the transformed data with a purely nonparametric logistic Gaussian process density prior. Based on Tokdar et al. (2022) <doi:10.1080/01621459.2022.2104727>.
This data-driven phylogenetic comparative method fits stabilizing selection models to continuous trait data, building on the ouch methodology of Butler and King (2004) <doi:10.1086/426002>. The main functions fit a series of Hansen models using stepwise AIC, then identify cases of convergent evolution where multiple lineages have shifted to the same adaptive peak. For more information see Ingram and Mahler (2013) <doi:10.1111/2041-210X.12034>.
Seamless and standardized interaction with data exported from the clinical data management system (CDMS) secuTrial'<https://www.secutrial.com>. The primary data export the package works with is a standard non-rectangular export.
Fitting the full likelihood proportional hazards model and extracting the residuals.
This package provides a computational framework for analyzing mutations in immunoglobulin (Ig) sequences. Includes methods for Bayesian estimation of antigen-driven selection pressure, mutational load quantification, building of somatic hypermutation (SHM) models, and model-dependent distance calculations. Also includes empirically derived models of SHM for both mice and humans. Citations: Gupta and Vander Heiden, et al (2015) <doi:10.1093/bioinformatics/btv359>, Yaari, et al (2012) <doi:10.1093/nar/gks457>, Yaari, et al (2013) <doi:10.3389/fimmu.2013.00358>, Cui, et al (2016) <doi:10.4049/jimmunol.1502263>.
Derives stratified prevalence tables from the condition, procedure, and drug records in OMOP CDM (Observational Medical Outcomes Partnership Common Data Model) databases, computes log2 prevalence ratios between paired datasets, and synthesizes them via random-effects meta-analysis at multiple aggregation levels (year, age group, and sex). Between-study variance is estimated with the Paule-Mandel method, as described in Paule and Mandel (1982) <doi:10.6028/jres.087.022>.
Provide estimation, simulation, and model selection tools for the skew-unit family discussed based on Mukhopadhyay and Brani (1995) <doi:10.2307/2348710>. The family contains extensions for popular distributions such as the ArcSin discussed in Arnold and Groeneveld (1980) <doi:10.1080/01621459.1980.10477449>, triangular, U-quadratic and Johnson-SB proposed in Cortina-Borja (2006) <doi:10.1111/j.1467-985X.2006.00446_12.x> distributions, among others.