HDF5 is a data model, library and file format for storing and managing large amounts of data. This package provides a nearly feature complete, object oriented wrapper for the HDF5 API using R6 classes. Additionally, functionality is added so that HDF5 objects behave very similar to their corresponding R counterparts.

This package is an R package designed for QC, analysis, and exploration of single cell RNA-seq data. It easily enables widely-used analytical techniques, including the identification of highly variable genes, dimensionality reduction; PCA, ICA, t-SNE, standard unsupervised clustering algorithms; density clustering, hierarchical clustering, k-means, and the discovery of differentially expressed genes and markers.

Common utilities used in other Mosaic family packages are collected here.

This package provides tools for regression subset selection, including exhaustive search.

It is sometimes useful to perform a computation in a separate R process, without affecting the current R process at all. This package does exactly that.

This package provides tools to fit and compare Gaussian linear and nonlinear mixed-effects models.

Performs unconditional exact tests and power calculations for 2x2 contingency tables. For comparing two independent proportions, performs Barnard's test (1945) using the original CSM test (Barnard (1947)), using Fisher's p-value referred to as Boschloo's test (1970), or using a Z-statistic (Suissa and Shuster (1985)). For comparing two binary proportions, performs unconditional exact test using McNemar's Z-statistic (Berger and Sidik (2003)), using McNemar's Z-statistic with continuity correction, or using CSM test. Calculates confidence intervals for the difference in proportion.

RcppDist provides a header-only C++ library with functions for additional statistical distributions that can be called from C++ when writing code using Rcpp or RcppArmadillo. Functions are available that return a NumericVector as well as doubles, and for multivariate or matrix distributions, Armadillo vectors and matrices.

This package can be used to solve Linear Programming / Linear Optimization problems by using the simplex algorithm.

This package provides functions to perform reproducible parallel foreach loops, using independent random streams as generated by L'Ecuyer's combined multiple-recursive generator. It enables to easily convert standard %dopar% loops into fully reproducible loops, independently of the number of workers, the task scheduling strategy, or the chosen parallel environment and associated foreach backend.

This package implements numerically-stable Gauss-Hermite quadrature rules and utility functions for adaptive GH quadrature.

This is a package for estimating the copula mixture model and plotting correspondence curves in "Measuring reproducibility of high-throughput experiments" (2011), Annals of Applied Statistics, Vol. 5, No. 3, 1752-1779, by Li, Brown, Huang, and Bickel

This package provides tools to integrate nucleotide sequencing data (variant call format, e.g. VCF or BCF) or meta-analysis results in R.

This package aims to provide easy-to-use, efficient, flexible and scalable statistical tools. It provides and uses file-backed big matrices via memory-mapping. It provides for instance matrix operations, Principal Component Analysis, sparse linear supervised models, utility functions and more.

This package provides a set of functions to analyze overdispersed counts or proportions. Most of the methods are already available elsewhere but are scattered in different packages. The proposed functions should be considered as complements to more sophisticated methods such as generalized estimating equations (GEE) or generalized linear mixed effect models (GLMM).

This package is a port of sofia-ml to R. Sofia-ml is a suite of fast incremental algorithms for machine learning that can be used for training models for classification or ranking.

This package provides a collection of tools to deal with statistical models. The functionality is experimental and the user interface is likely to change in the future.

This package provides a basic set of R functions for querying the Cancer Genomics Data Server (CGDS), hosted by the Computational Biology Center at Memorial-Sloan-Kettering Cancer Center (MSKCC).

This package provides a convenience wrapper that uses the rmarkdown package to render small snippets of code to target formats that include both code and output. The goal is to encourage the sharing of small, reproducible, and runnable examples on code-oriented websites or email. reprex also extracts clean, runnable R code from various common formats, such as copy/paste from an R session.

This package estimates previously compiled regression models using the rstan package, which provides the R interface to the Stan C++ library for Bayesian estimation. Users specify models via the customary R syntax with a formula and data.frame plus some additional arguments for priors.

This package provides David Scott's ASH routines ported from S-PLUS to R.

This package allows users to test characteristics of common R objects.

This is a subset of the spatstat package, containing its functionality for spatial data on a linear network.

High dimensional interaction search by brute force requires a quadratic computational cost in the number of variables. The xyz algorithm provably finds strong interactions in almost linear time. For details of the algorithm see: G. Thanei, N. Meinshausen and R. Shah (2016). The xyz algorithm for fast interaction search in high-dimensional data.