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This package provides tools for plotting gene clusters and transcripts by importing data from GenBank, FASTA, and GFF files. It performs BLASTP and MUMmer alignments [Altschul et al. (1990) <doi:10.1016/S0022-2836(05)80360-2>; Delcher et al. (1999) <doi:10.1093/nar/27.11.2369>] and displays results on gene arrow maps. Extensive customization options are available, including legends, labels, annotations, scales, colors, tooltips, and more.
Generalized factor model is implemented for ultra-high dimensional data with mixed-type variables. Two algorithms, variational EM and alternate maximization, are designed to implement the generalized factor model, respectively. The factor matrix and loading matrix together with the number of factors can be well estimated. This model can be employed in social and behavioral sciences, economy and finance, and genomics, to extract interpretable nonlinear factors. More details can be referred to Wei Liu, Huazhen Lin, Shurong Zheng and Jin Liu. (2021) <doi:10.1080/01621459.2021.1999818>.
An extension of ggplot2 that makes it easy to add raw grid output, such as customised annotations, to a ggplot2 plot.
Fit linear mixed-effects models using restricted (or residual) maximum likelihood (REML) and with generalized inverse matrices to specify covariance structures for random effects. In particular, the package is suited to fit quantitative genetic mixed models, often referred to as animal models'. Implements the average information algorithm as the main tool to maximize the restricted log-likelihood, but with other algorithms available.
Wrappers for functions in the gRain package to emulate some RHugin functionality, allowing the building of Bayesian networks consisting on discrete chance nodes incrementally, through adding nodes, edges and conditional probability tables, the setting of evidence, both hard (boolean) or soft (likelihoods), querying marginal probabilities and normalizing constants, and generating sets of high-probability configurations. Computations will typically not be so fast as they are with RHugin', but this package should assist users without access to Hugin to use code written to use RHugin'.
Supplies a set of functions to interface with bikeshare data following the General Bikeshare Feed Specification, allowing users to query and accumulate tidy datasets for specified cities/bikeshare programs.
It provides a better alternative for stacked bar plot by creating a segmented total bar plot with custom annotations and labels. It is useful for visualizing the total of a variable and its segments in a single bar, making it easier to compare the segments and their contributions to the total.
Supply implementation to model generalized multivariate functional data using Bayesian additive mixed models of R package bamlss via a latent Gaussian process (see Umlauf, Klein, Zeileis (2018) <doi:10.1080/10618600.2017.1407325>).
This package provides a function built on ggplot2 that visualizes pairwise BLAST alignment results as chord diagrams, intuitively displaying homologous regions between query and subject sequences.
Graphical approach provides a useful framework for multiplicity adjustment in clinical trials with multiple endpoints. This package includes statistical methods to optimize sample size over initial weight and transition probability in a graphical approach under a common setting, which is to use marginal power for each endpoint in a trial design. See Zhang, F. and Gou, J. (2023). Sample size optimization for clinical trials using graphical approaches for multiplicity adjustment, Technical Report.
Simple interface to query gitignore.io to fetch gitignore templates that can be included in the .gitignore file. More than 450 templates are currently available.
Interfaces GAMS data (*.gdx) files with data.table's using the GAMS R package gdxrrw'. The gdxrrw package is available on the GAMS wiki: <https://support.gams.com/doku.php?id=gdxrrw:interfacing_gams_and_r>.
This package provides the following types of models: Models for contingency tables (i.e. log-linear models) Graphical Gaussian models for multivariate normal data (i.e. covariance selection models) Mixed interaction models. Documentation about gRim is provided by vignettes included in this package and the book by Højsgaard, Edwards and Lauritzen (2012, <doi:10.1007/978-1-4614-2299-0>); see citation("gRim") for details.
This package provides a genetic algorithm for finding variable subsets in high dimensional data with high prediction performance. The genetic algorithm can use ordinary least squares (OLS) regression models or partial least squares (PLS) regression models to evaluate the prediction power of variable subsets. By supporting different cross-validation schemes, the user can fine-tune the tradeoff between speed and quality of the solution.
Find all hierarchical models of specified generalized linear model with information criterion (AIC, BIC, or AICc) within specified cutoff of minimum value. Alternatively, find all such graphical models. Use branch and bound algorithm so we do not have to fit all models.
This package implements readers and writers for file formats associated with genetics data. Reading and writing Plink BED/BIM/FAM and GCTA binary GRM formats is fully supported, including a lightning-fast BED reader and writer implementations. Other functions are readr wrappers that are more constrained, user-friendly, and efficient for these particular applications; handles Plink and Eigenstrat tables (FAM, BIM, IND, and SNP files). There are also make functions for FAM and BIM tables with default values to go with simulated genotype data.
Data sets and scripts used in the book Generalized Additive Models: An Introduction with R', Wood (2006,2017) CRC.
Identifies biomarkers that exhibit differential response dynamics by time across groups and estimates kinetic properties of biomarkers.
Sequential change-point tests, parameters estimation, and goodness-of-fit tests for generalized Ornstein-Uhlenbeck processes.
This package provides a method to predict and report gender from Brazilian first names using the Brazilian Institute of Geography and Statistics Census data (<https://censo2010.ibge.gov.br/nomes/>).
Accurate and computationally efficient p-value calculation methods for a general family of Fisher type statistics (GFisher). The GFisher covers Fisher's combination, Good's statistic, Lancaster's statistic, weighted Z-score combination, etc. It allows a flexible weighting scheme, as well as an omnibus procedure that automatically adapts proper weights and degrees of freedom to a given data. The new p-value calculation methods are based on novel ideas of moment-ratio matching and joint-distribution approximation. The technical details can be found in Hong Zhang and Zheyang Wu (2020) <arXiv:2003.01286>.
This package purposes to deal with public survey data of Japanese government via their Application Programming Interface (http://statdb.nstac.go.jp/).
Computes the probability density function (pdf), cumulative distribution function (cdf), quantile function (qf) and generates random values (rg) for the following general models : mixture models, composite models, folded models, skewed symmetric models and arc tan models.
Includes a collection of geographical analysis functions aimed primarily at ecology and conservation science studies, allowing processing of both point and raster data. Now integrates SPECTRE (<https://biodiversityresearch.org/spectre/>), a dataset of global geospatial threat data, developed by the authors.