The heterogeneous treatment effect estimation procedure proposed by Imai and Ratkovic (2013)<DOI: 10.1214/12-AOAS593>. The proposed method is applicable, for example, when selecting a small number of most (or least) efficacious treatments from a large number of alternative treatments as well as when identifying subsets of the population who benefit (or are harmed by) a treatment of interest. The method adapts the Support Vector Machine classifier by placing separate LASSO constraints over the pre-treatment parameters and causal heterogeneity parameters of interest. This allows for the qualitative distinction between causal and other parameters, thereby making the variable selection suitable for the exploration of causal heterogeneity. The package also contains a class of functions, CausalANOVA, which estimates the average marginal interaction effects (AMIEs) by a regularized ANOVA as proposed by Egami and Imai (2019). It contains a variety of regularization techniques to facilitate analysis of large factorial experiments.

This package implements shape-based clustering algorithms for multidimensional longitudinal data based on the Fréchet distance. It implements two main methods: MFKmL (Multidimensional Fréchet distance-based K-means for Longitudinal data), an extension of the K-means algorithm using the Fréchet distance originally developed in the kmlShape package, adapted for multidimensional trajectories; and SFKmL (Sparse multidimensional Fréchet distance-based K-medoids for Longitudinal data), a K-medoids-based clustering algorithm that incorporates variable selection. These tools are designed to enhance clustering performance in high-dimensional longitudinal data settings, particularly those with time delays, variations in trajectory speed, irregular sampling intervals, and noise. This package implements methods derived from Kang et al. (2023) <doi:10.1007/s11222-023-10237-z>.

Analysis of Fluorescence Recovery After Photobleaching (FRAP) experiments using nonlinear mixed-effects regression models and analysis of the results. FRApp is not limited to the analysis of FRAP experiments only. Any nonlinear mixed-effects models with an asymptotic exponential functional relationship to hierarchical data in various domains can be fitted. The analysis of data available in the package is presented in Di Credico, G., Pelucchi, S., Pauli, F. et al. (2025) <doi:10.1038/s41598-025-87154-w>.

An R client for the "fixer.io" currency conversion and exchange rate API. The API requires registration and some features are only available on paid accounts. The full API documentation is available at <https://fixer.io/documentation>.

It implements an improved and computationally faster version of the original Stepwise Gaussian Graphical Algorithm for estimating the Omega precision matrix from high-dimensional data. Zamar, R., Ruiz, M., Lafit, G. and Nogales, J. (2021) <doi:10.52933/jdssv.v1i2.11>.

This package provides tools to quickly compile taxonomic and distribution data from the Brazilian Flora 2020.

This package performs dose assignment and trial simulation for the FBCRM (Fully Bayesian Continual Reassessment Method) and MFBCRM (Mixture Fully Bayesian Continual Reassessment Method) phase I clinical trial designs. These trial designs extend the Continual Reassessment Method (CRM) and Bayesian Model Averaging Continual Reassessment Method (BMA-CRM) by allowing the prior toxicity skeleton itself to be random, with posterior distributions obtained from Markov Chain Monte Carlo. On average, the FBCRM and MFBCRM methods outperformed the CRM and BMA-CRM methods in terms of selecting an optimal dose level across thousands of randomly generated simulation scenarios. Details on the methods and results of this simulation study are available on request, and the manuscript is currently under review.

This package provides functions for creating, analyzing, and visualizing event study models using fixed-effects regression. Supports staggered adoption, multiple confidence intervals, flexible clustering, and panel/time transformations in a simple workflow.

This package provides functions for the flexible integration of heterogeneous scRNA-seq datasets across multiple tissue types, platforms, and experimental batches. Implements the method described in Ming (2022) <doi:10.1093/bib/bbac167>. The package incorporates modified C++ source code from the flashpca library (Abraham, 2014-2016 <https://github.com/gabraham/flashpca>) for efficient principal component analysis, and the Spectra library (Qiu, 2016-2025) for large-scale eigenvalue and singular value decomposition; see inst/COPYRIGHTS for details on third-party code.

Calculates the fused extended two-way fixed effects (FETWFE) estimator for unbiased and efficient estimation of difference-in-differences in panel data with staggered treatment adoption. This estimator eliminates bias inherent in conventional two-way fixed effects estimators, while also employing a novel bridge regression regularization approach to improve efficiency and yield valid standard errors. Also implements extended TWFE (etwfe) and bridge-penalized ETWFE (betwfe). Provides S3 classes for streamlined workflow and supports flexible tuning (ridge and rank-condition guarantees), automatic covariate centering/scaling, and detailed overall and cohort-specific effect estimates with valid standard errors. Includes simulation and formatting utilities, extensive diagnostic tools, vignettes, and examples. See Faletto (2025) (<doi:10.48550/arXiv.2312.05985>).

This package provides tools for quickly processing and analyzing field observation data and air quality data. This tools contain functions that facilitate analysis in atmospheric chemistry (especially in ozone pollution). Some functions of time series are also applicable to other fields. For detail please view homepage<https://github.com/tianshu129/foqat>. Scientific Reference: 1. The Hydroxyl Radical (OH) Reactivity: Roger Atkinson and Janet Arey (2003) <doi:10.1021/cr0206420>. 2. Ozone Formation Potential (OFP): <http://ww2.arb.ca.gov/sites/default/files/barcu/regact/2009/mir2009/mir10.pdf>, Zhang et al.(2021) <doi:10.5194/acp-21-11053-2021>. 3. Aerosol Formation Potential (AFP): Wenjing Wu et al. (2016) <doi:10.1016/j.jes.2016.03.025>. 4. TUV model: <https://www2.acom.ucar.edu/modeling/tropospheric-ultraviolet-and-visible-tuv-radiation-model>.

Developed by CDC/ATSDR (Centers for Disease Control and Prevention/ Agency for Toxic Substances and Disease Registry), Social Vulnerability Index (SVI) serves as a tool to assess the resilience of communities by taking into account socioeconomic and demographic factors. Provided with year(s), region(s) and a geographic level of interest, findSVI retrieves required variables from US census data and calculates SVI for communities in the specified area based on CDC/ATSDR SVI documentation. Reference for the calculation methods: Flanagan BE, Gregory EW, Hallisey EJ, Heitgerd JL, Lewis B (2011) <doi:10.2202/1547-7355.1792>.

Samples generalized random product graphs, a generalization of a broad class of network models. Given matrices X, S, and Y with with non-negative entries, samples a matrix with expectation X S Y^T and independent Poisson or Bernoulli entries using the fastRG algorithm of Rohe et al. (2017) <https://www.jmlr.org/papers/v19/17-128.html>. The algorithm first samples the number of edges and then puts them down one-by-one. As a result it is O(m) where m is the number of edges, a dramatic improvement over element-wise algorithms that which require O(n^2) operations to sample a random graph, where n is the number of nodes.

Probabilistic distance clustering (PD-clustering) is an iterative, distribution-free, probabilistic clustering method. PD-clustering assigns units to a cluster according to their probability of membership under the constraint that the product of the probability and the distance of each point to any cluster center is a constant. PD-clustering is a flexible method that can be used with elliptical clusters, outliers, or noisy data. PDQ is an extension of the algorithm for clusters of different sizes. GPDC and TPDC use a dissimilarity measure based on densities. Factor PD-clustering (FPDC) is a factor clustering method that involves a linear transformation of variables and a cluster optimizing the PD-clustering criterion. It works on high-dimensional data sets.

To help you access, transform, analyze, and visualize ForestGEO data, we developed a collection of R packages (<https://forestgeo.github.io/fgeo/>). This package, in particular, helps you to implement analyses of plot species distributions, topography, demography, and biomass. It also includes a torus translation test to determine habitat associations of tree species as described by Zuleta et al. (2018) <doi:10.1007/s11104-018-3878-0>. To learn more about ForestGEO visit <https://forestgeo.si.edu/>.

This package provides a guarded resampling workflow for training and evaluating machine-learning models. When the guarded resampling path is used, preprocessing and model fitting are re-estimated within each resampling split to reduce leakage risk. Supports multiple resampling schemes, integrates with established engines in the tidymodels ecosystem, and aims to improve evaluation reliability by coordinating preprocessing, fitting, and evaluation within supported workflows. Offers a lightweight AutoML-style workflow by automating model training, resampling, and tuning across multiple algorithms, while keeping evaluation design explicit and user-controlled.

This package provides methods for matrix factorization based on Wang and Stephens (2021) <https://jmlr.org/papers/v22/20-589.html>.

Routines for the estimation or simultaneous estimation and variable selection in several functional semiparametric models with scalar responses are provided. These models include the functional single-index model, the semi-functional partial linear model, and the semi-functional partial linear single-index model. Additionally, the package offers algorithms for handling scalar covariates with linear effects that originate from the discretization of a curve. This functionality is applicable in the context of the linear model, the multi-functional partial linear model, and the multi-functional partial linear single-index model.

Optimal experimental designs for functional linear and functional generalised linear models, for scalar responses and profile/dynamic factors. The designs are optimised using the coordinate exchange algorithm. The methods are discussed by Michaelides (2023) <https://eprints.soton.ac.uk/474982/1/Thesis_DamianosMichaelides_Final_pdfa_1_.pdf>.

Parse static-chamber greenhouse gas measurement files generated by a variety of instruments; compute flux rates using multi-observation metadata; and generate diagnostic metrics and plots. Designed to be easy to integrate into reproducible scientific workflows.

This package provides a wrapper for the API of the Danish Parliament. It makes it possible to get data from the API easily into a data frame. Learn more at <http://www.ft.dk/dokumenter/aabne_data>.

This package provides tools to study lineages, grandparenthood, loss of close relatives, kinship networks and other topics in multi-generation populations.

Estimation and inference using the Fractionally Cointegrated Vector Autoregressive (VAR) model. It includes functions for model specification, including lag selection and cointegration rank selection, as well as a comprehensive set of options for hypothesis testing, including tests of hypotheses on the cointegrating relations, the adjustment coefficients and the fractional differencing parameters. An article describing the FCVAR model with examples is available on the Webpage <https://sites.google.com/view/mortennielsen/software>.

An implementation of regression models with partial differential regularizations, making use of the Finite Element Method. The models efficiently handle data distributed over irregularly shaped domains and can comply with various conditions at the boundaries of the domain. A priori information about the spatial structure of the phenomenon under study can be incorporated in the model via the differential regularization. See Sangalli, L. M. (2021) <doi:10.1111/insr.12444> "Spatial Regression With Partial Differential Equation Regularisation" for an overview. The release 1.1-9 requires R (>= 4.2.0) to be installed on windows machines.