This package provides a screening process utilizing training and testing samples to filter out uninformative DNA methylation sites. Surrogate variables (SVs) of DNA methylation are included in the filtering process to explain unknown factor effects. This package also provides two screening functions for screening high-dimensional predictors when the events are rare. The firth method is called Rare-Screening which employs a repeated random sampling with replacement and using linear modeling with Bayes adjustment. The Second method is called Firth-ttScreening which uses ttScreening method with additional Firth correction term in the maximum likelihood for the logistic regression model. These methods handle the high-dimensionality and low event rates.

This package provides a novel feature-wise normalization method based on a zero-inflated negative binomial model. This method assumes that the effects of sequencing depth vary for each taxon on their mean and also incorporates a rational link of zero probability and taxon dispersion as a function of sequencing depth. Ziyue Wang, Dillon Lloyd, Shanshan Zhao, Alison Motsinger-Reif (2023) <doi:10.1101/2023.10.31.563648>.

Bootstrapped response and correlation functions, seasonal correlations and evaluation of reconstruction skills for use in dendroclimatology and dendroecology, see Zang and Biondi (2015) <doi:10.1111/ecog.01335>.

This package performs model-based tensor clustering methods including Tensor Gaussian Mixture Model (TGMM), Tensor Envelope Mixture Model (TEMM) by Deng and Zhang (2021) <DOI: 10.1111/biom.13486>, Doubly-Enhanced EM (DEEM) algorithm by Mai, Zhang, Pan and Deng (2021) <DOI: 10.1080/01621459.2021.1904959>.

Tests one hypothesis with several test statistics, correcting for multiple testing. The central function in the package is testtwice(). In a sensitivity analysis, the method has the largest design sensitivity of its component tests. The package implements the method and examples in Rosenbaum, P. R. (2012) <doi:10.1093/biomet/ass032> Testing one hypothesis twice in observational studies. Biometrika, 99(4), 763-774.

Fitting time-varying coefficient models for single and multi-equation regressions, using kernel smoothing techniques.

An implementation of the Thornley transport resistance plant growth model. The package can be used to simulate plant growth as forced by climate system variables. The package provides methods for formatting forcing variables, simulating growth dynamics and calibrating model parameters. For more information see Higgins et al. (2025) TTR.PGM: An R package for modelling the distributions and dynamics of plants using the Thornley transport resistance plant growth model. Methods in Ecology and Evolution. in press.

Calculates topic-specific diagnostics (e.g. mean token length, exclusivity) for Latent Dirichlet Allocation and Correlated Topic Models fit using the topicmodels package. For more details, see Chapter 12 in Airoldi et al. (2014, ISBN:9781466504080), pp 262-272 Mimno et al. (2011, ISBN:9781937284114), and Bischof et al. (2014) <arXiv:1206.4631v1>.

Converts coefficients, standard errors, significance stars, and goodness-of-fit statistics of statistical models into LaTeX tables or HTML tables/MS Word documents or to nicely formatted screen output for the R console for easy model comparison. A list of several models can be combined in a single table. The output is highly customizable. New model types can be easily implemented. Details can be found in Leifeld (2013), JStatSoft <doi:10.18637/jss.v055.i08>.).

This package provides conditional maximum likelihood (CML) item parameter estimation of both sequential and cumulative deterministic multistage designs (Zwitser & Maris, 2015, <doi:10.1007/s11336-013-9369-6>) and probabilistic sequential and cumulative multistage designs (Steinfeld & Robitzsch, 2024, <doi:10.1007/s41237-024-00228-3>). Supports CML item parameter estimation of conventional linear designs and additional functions for the likelihood ratio test (Andersen, 1973, <doi:10.1007/BF02291180>) as well as functions for simulating various types of multistage designs.

This is a small package to provide consistent tick marks for plotting ggplot2 figures. It provides breaks and labels for ggplot2 without requiring ggplot2 to be installed.

This package provides tools to help developers and producers manipulate R objects and outputs. It includes tools for displaying results and objects, and for formatting them in the correct format.

Function for sparse regression on raw text, regressing a labeling vector onto a feature space consisting of all possible phrases.

Helper functions for MASCOTNUM / RT-UQ <https://uq.math.cnrs.fr/> algorithm template, for design of numerical experiments practice: algorithm template parser to support MASCOTNUM specification <https://github.com/MASCOTNUM/algorithms>, ask & tell decoupling injection (inspired by <https://search.r-project.org/CRAN/refmans/sensitivity/html/decoupling.html>) to use "crimped" algorithms (like uniroot(), optim(), ...) from outside R, basic template examples: Brent algorithm for 1 dim root finding and L-BFGS-B from base optim().

The trapezoid package provides dtrapezoid', ptrapezoid', qtrapezoid', and rtrapezoid functions for the trapezoidal distribution.

This package provides a teal_data class as a unified data model for teal applications focusing on reproducibility and relational data.

Our method introduces mathematically well-defined measures for tightness of branches in a hierarchical tree. Statistical significance of the findings is determined, for all branches of the tree, by performing permutation tests, optionally with generalized Pareto p-value estimation.

Estimate and return either the traffic speed or the car entries in the city of Thessaloniki using historical traffic data. It's used in transport pilot of the BigDataEurope project. There are functions for processing these data, training a neural network, select the most appropriate model and predict the traffic speed or the car entries for a selected time date.

Gene and exon information from Ensembl genome builds GRCh38.p13 (104) and GRCh37 (v40) to use with the topr package.

This package provides a general framework of two directional simultaneous inference is provided for high-dimensional as well as the fixed dimensional models with manifest variable or latent variable structure, such as high-dimensional mean models, high- dimensional sparse regression models, and high-dimensional latent factors models. It is making the simultaneous inference on a set of parameters from two directions, one is testing whether the estimated zero parameters indeed are zero and the other is testing whether there exists zero in the parameter set of non-zero. More details can be referred to Wei Liu, et al. (2022) <doi:10.48550/arXiv.2012.11100>.

Trust region algorithm for nonlinear optimization. Efficient when the Hessian of the objective function is sparse (i.e., relatively few nonzero cross-partial derivatives). See Braun, M. (2014) <doi:10.18637/jss.v060.i04>.

This package provides a convenient R interface to the National Health Service NHS Technology Reference Update Distribution (TRUD) API', allowing users to list available releases for their subscribed items, retrieve metadata, and download release files. For more information on the API, see <https://isd.digital.nhs.uk/trud/users/guest/filters/0/api>.

Helps the user to build and register schema descriptions of disorganised (messy) tables. Disorganised tables are tables that are not in a topologically coherent form, where packages such as tidyr could be used for reshaping. The schema description documents the arrangement of input tables and is used to reshape them into a standardised (tidy) output format.

Converting structured data from tables into XML format using predefined templates ensures consistency and flexibility, making it ideal for data exchange, reporting, and automated workflows.