Draws gene or genome maps and comparisons between these, in a publication-grade manner. Starting from simple, common files, it will draw postscript or PDF files that can be sent as such to journals.

An implementation of maximum simulated likelihood method for the estimation of multinomial logit models with random coefficients as presented by Sarrias and Daziano (2017) <doi:10.18637/jss.v079.i02>. Specifically, it allows estimating models with continuous heterogeneity such as the mixed multinomial logit and the generalized multinomial logit. It also allows estimating models with discrete heterogeneity such as the latent class and the mixed-mixed multinomial logit model.

This package provides a simple, opinionated toolkit for visualizing genomic variant data using a ggplot2'-native grammar. Accepts VCF files or plain data frames and produces publication-ready lollipop plots, consequence summaries, mutational spectrum charts, and cohort-level comparisons with minimal code. Designed for both wet-lab biologists and experienced bioinformaticians.

Gaussian processes are flexible distributions to model functional data. Whilst theoretically appealing, they are computationally cumbersome except for small datasets. This package implements two methods for scaling Gaussian process inference in Stan'. First, a sparse approximation of the likelihood that is generally applicable and, second, an exact method for regularly spaced data modeled by stationary kernels using fast Fourier methods. Utility functions are provided to compile and fit Stan models using the cmdstanr interface. References: Hoffmann and Onnela (2025) <doi:10.18637/jss.v112.i02>.

Generation of survival data with one (binary) time-dependent covariate. Generation of survival data arising from a progressive illness-death model.

This package contains the framework of the estimation, sampling, and hypotheses testing for two special distributions (Exponentiated Exponential-Pareto and Exponentiated Inverse Gamma-Pareto) within the family of Generalized Exponentiated Composite distributions. The detailed explanation and the applications of these two distributions were introduced in Bowen Liu, Malwane M.A. Ananda (2022) <doi:10.1080/03610926.2022.2050399>, Bowen Liu, Malwane M.A. Ananda (2022) <doi:10.3390/math10111895>, and Bowen Liu, Malwane M.A. Ananda (2022) <doi:10.3390/app13010645>.

Implementations of the algorithms present article Generalized Spatial-Time Sequence Miner, original title (Castro, Antonio; Borges, Heraldo ; Pacitti, Esther ; Porto, Fabio ; Coutinho, Rafaelli ; Ogasawara, Eduardo . Generalização de Mineração de Sequências Restritas no Espaço e no Tempo. In: XXXVI SBBD - Simpósio Brasileiro de Banco de Dados, 2021 <doi:10.5753/sbbd.2021.17891>).

This package provides a novel statistical model to detect the joint genetic and dynamic gene-environment (GxE) interaction with continuous traits in genetic association studies. It uses varying-coefficient models to account for different GxE trajectories, regardless whether the relationship is linear or not. The package includes one function, GxEtest(), to test a single genetic variant (e.g., a single nucleotide polymorphism or SNP), and another function, GxEscreen(), to test for a set of genetic variants. The method involves a likelihood ratio test described in Crainiceanu, C. M., and Ruppert, D. (2004) <doi:10.1111/j.1467-9868.2004.00438.x>.

An event-Based framework for building Shiny apps. Instead of relying on standard Shiny reactive objects, this package allow to relying on a lighter set of triggers, so that reactive contexts can be invalidated with more control.

Generalized Order-Restricted Information Criterion (GORIC) value for a set of hypotheses in multivariate linear models and generalised linear models.

This package performs genetic algorithm (Scrucca, L (2013) <doi:10.18637/jss.v053.i04>) assisted genomic best liner unbiased prediction for genomic selection. It also provides a binning method in natural population for genomic selection under the principle of linkage disequilibrium for dimensional reduction.

This package provides functions are provided for quantifying evolution and selection on complex traits. The package implements effective handling and analysis algorithms scaled for genome-wide data and calculates a composite statistic, denoted Ghat, which is used to test for selection on a trait. The package provides a number of simple examples for handling and analysing the genome data and visualising the output and results. Beissinger et al., (2018) <doi:10.1534/genetics.118.300857>.

Bayesian nonlinear regression under a range of likelihood models using generalized Bayesian adaptive smoothing splines. Robust regression with Student's t likelihoods, quantile regression, and related latent-scale models are included as special cases.

This package provides stat_isotonic() to add weighted univariate isotonic regression curves.

Connecting spatiotemporal exposure to individual and population-level risk via source-to-outcome continuum modeling. The package, methods, and case-studies are described in Messier, Reif, and Marvel (2025) <doi:10.1186/s40246-024-00711-8> and Eccles et al. (2023) <doi:10.1016/j.scitotenv.2022.158905>.

The accurate annotation of genes and Quantitative Trait Loci (QTLs) located within candidate markers and/or regions (haplotypes, windows, CNVs, etc) is a crucial step the most common genomic analyses performed in livestock, such as Genome-Wide Association Studies or transcriptomics. The Genomic Annotation in Livestock for positional candidate LOci (GALLO) is an R package designed to provide an intuitive and straightforward environment to annotate positional candidate genes and QTLs from high-throughput genetic studies in livestock. Moreover, GALLO allows the graphical visualization of gene and QTL annotation results, data comparison among different grouping factors (e.g., methods, breeds, tissues, statistical models, studies, etc.), and QTL enrichment in different livestock species including cattle, pigs, sheep, and chicken, among others.

Utilities to cost and evaluate Australian tax policy, including fast projections of personal income tax collections, high-performance tax and transfer calculators, and an interface to common indices from the Australian Bureau of Statistics. Written to support Grattan Institute's Australian Perspectives program, and related projects. Access to the Australian Taxation Office's sample files of personal income tax returns is assumed.

The GeneCycle package implements the approaches of Wichert et al. (2004) <doi:10.1093/bioinformatics/btg364>, Ahdesmaki et al. (2005) <doi:10.1186/1471-2105-6-117> and Ahdesmaki et al. (2007) <DOI:10.1186/1471-2105-8-233> for detecting periodically expressed genes from gene expression time series data.

This package provides a simple API for downloading and reading xml data directly from Lattes <http://lattes.cnpq.br/>.

The aim of this package is to offer more variability of graphics based on the self-organizing maps.

This package provides functions for performing graphical difference testing. Differences are generated between raster images. Comparisons can be performed between different package versions and between different R versions.

Conducts hierarchical partitioning to calculate individual contributions of each predictor towards adjusted R2 and explained deviance for generalized additive models based on output of gam() and bam() in mgcv package, applying the algorithm in this paper: Lai(2024) <doi:10.1016/j.pld.2024.06.002>.

Understanding how features influence a specific response variable becomes crucial in classification problems, with applications ranging from medical diagnosis to customer behavior analysis. This packages provides tools to compute such an influence measure grounded on game theory concepts. In particular, the influence measures presented in Davila-Pena, Saavedra-Nieves, and Casas-Méndez (2024) <doi:10.48550/arXiv.2408.02481> can be obtained.

We propose a fully efficient sieve maximum likelihood method to estimate genotype-specific distribution of time-to-event outcomes under a nonparametric model. We can handle missing genotypes in pedigrees. We estimate the time-dependent hazard ratio between two genetic mutation groups using B-splines, while applying nonparametric maximum likelihood estimation to the reference baseline hazard function. The estimators are calculated via an expectation-maximization algorithm.