This package provides the ability to create interaction maps, discover CNV map domains (edges), gene annotate interactions, and create interactive visualizations of these CNV interaction maps.

This package provides a collection of functions to pre-process amplification curve data from polymerase chain reaction (PCR) or isothermal amplification reactions. Contains functions to normalize and baseline amplification curves, to detect both the start and end of an amplification reaction, several smoothers (e.g., LOWESS, moving average, cubic splines, Savitzky-Golay), a function to detect false positive amplification reactions and a function to determine the amplification efficiency. Quantification point (Cq) methods include the first (FDM) and second approximate derivative maximum (SDM) methods (calculated by a 5-point-stencil) and the cycle threshold method. Data sets of experimental nucleic acid amplification systems ('VideoScan HCU', capillary convective PCR (ccPCR)) and commercial systems are included. Amplification curves were generated by helicase dependent amplification (HDA), ccPCR or PCR. As detection system intercalating dyes (EvaGreen, SYBR Green) and hydrolysis probes (TaqMan) were used. For more information see: Roediger et al. (2015) <doi:10.1093/bioinformatics/btv205>.

Computes conditional multivariate normal densities, probabilities, and random deviates.

This package provides tools for analyzing performances of cricketers based on stats in ESPN Cricinfo Statsguru. The toolset can be used for analysis of Tests,ODIs and Twenty20 matches of both batsmen and bowlers. The package can also be used to analyze team performances.

Cellular cooperation compromises the plating efficiency-based analysis of clonogenic survival data. This tool provides functions that enable a robust analysis of colony formation assay (CFA) data in presence or absence of cellular cooperation. The implemented method has been described in Brix et al. (2020). (Brix, N., Samaga, D., Hennel, R. et al. "The clonogenic assay: robustness of plating efficiency-based analysis is strongly compromised by cellular cooperation." Radiat Oncol 15, 248 (2020). <doi:10.1186/s13014-020-01697-y>) Power regression for parameter estimation, calculation of survival fractions, uncertainty analysis and plotting functions are provided.

Users can declare causal models over binary nodes, update beliefs about causal types given data, and calculate arbitrary queries. Updating is implemented in stan'. See Humphreys and Jacobs, 2023, Integrated Inferences (<DOI: 10.1017/9781316718636>) and Pearl, 2009 Causality (<DOI:10.1017/CBO9780511803161>).

This package provides a method for determining groups in multiple curves with an automatic selection of their number based on k-means or k-medians algorithms. The selection of the optimal number is provided by bootstrap methods. The methodology can be applied both in regression and survival framework. Implemented methods are: Grouping multiple survival curves described by Villanueva et al. (2018) <doi:10.1002/sim.8016>.

Adjusts the loglikelihood of common econometric models for clustered data based on the estimation process suggested in Chandler and Bate (2007) <doi:10.1093/biomet/asm015>, using the chandwich package <https://cran.r-project.org/package=chandwich>, and provides convenience functions for inference on the adjusted models.

Hierarchical and partitioning algorithms to cluster blocks of variables. The partitioning algorithm includes an option called noise cluster to set aside atypical blocks of variables. Different thresholds per cluster can be sets. The CLUSTATIS method (for quantitative blocks) (Llobell, Cariou, Vigneau, Labenne & Qannari (2020) <doi:10.1016/j.foodqual.2018.05.013>, Llobell, Vigneau & Qannari (2019) <doi:10.1016/j.foodqual.2019.02.017>) and the CLUSCATA method (for Check-All-That-Apply data) (Llobell, Cariou, Vigneau, Labenne & Qannari (2019) <doi:10.1016/j.foodqual.2018.09.006>, Llobell, Giacalone, Labenne & Qannari (2019) <doi:10.1016/j.foodqual.2019.05.017>) are the core of this package. The CATATIS methods allows to compute some indices and tests to control the quality of CATA data. Multivariate analysis and clustering of subjects for quantitative multiblock data, CATA, RATA, Free Sorting and JAR experiments are available. Clustering of rows in multi-block context (notably with ClusMB strategy) is also included.

This package provides a shiny app to discover cocktails. The app allows one to search for cocktails by ingredient, filter on rating, and number of ingredients. The package also contains data with the ingredients of nearly 26 thousand cocktails scraped from the web.

Flexible framework for trait-based simulation of community assembly, where components could be replaced by user-defined function and that allows variation of traits within species.

Routines for the graphical representation of correlation matrices by means of correlograms, MDS maps and biplots obtained by PCA, PFA or WALS (weighted alternating least squares); See Graffelman & De Leeuw (2023) <doi: 10.1080/00031305.2023.2186952>.

This package provides a simple way to manage application settings by loading configuration values from .env or .ini files. It supports default values, type casting, and environment variable overrides, enabling a clean separation of configuration from code. Ideal for managing credentials, API keys, and deployment-specific settings.

This package implements a semi-parametric GEE estimator accounting for missing data with Inverse-probability weighting (IPW) and for imbalance in covariates with augmentation (AUG). The estimator IPW-AUG-GEE is Doubly robust (DR).

An automated and streamlined workflow for predictive climate mapping using climate station data. Works within an environment the user provides a destined path to - otherwise it's tempdir(). Quick and relatively easy creation of resilient and reproducible climate models, predictions and climate maps, shortening the usually long and complicated work of predictive modelling. For more information, please find the provided URL. Many methods in this package are new, but the main method is based on a workflow from Meyer (2019) <doi:10.1016/j.ecolmodel.2019.108815> and Meyer (2022) <doi:10.1038/s41467-022-29838-9> , however, it was generalized and adjusted in the context of this package.

Interactive shiny application for running classical test theory (item analysis).

This package provides functions and Data to support Context Driven Exploratory Projection Pursuit.

Central limit theorem experiments presented by data frames or plots. Functions include generating theoretical sample space, corresponding probability, and simulated results as well.

This package provides a collection of tools to easily analyze clinical data, including functions for correlation analysis, and statistical testing. The package facilitates the integration of clinical metadata with other omics layers, enabling exploration of quantitative variables. It also includes the utility for frequency matching samples across a dataset based on patient variables.

Publicly available COVID-19 data for Norway cleaned and merged into one dataset, including PCR confirmed cases, tests, hospitalisation and vaccination.

Check your R code for some of the most common layout flaws. Many tried to teach us how to write code less dreadful, be it implicitly as B. W. Kernighan and D. M. Ritchie (1988) <ISBN:0-13-110362-8> in The C Programming Language did, be it explicitly as R.C. Martin (2008) <ISBN:0-13-235088-2> in Clean Code: A Handbook of Agile Software Craftsmanship did. So we should check our code for files too long or wide, functions with too many lines, too wide lines, too many arguments or too many levels of nesting. Note: This is not a static code analyzer like pylint or the like. Checkout <https://cran.r-project.org/package=lintr> instead.

This package performs survival analysis using general non-linear models. Risk models can be the sum or product of terms. Each term is the product of exponential/linear functions of covariates. Additionally sub-terms can be defined as a sum of exponential, linear threshold, and step functions. Cox Proportional hazards, Poisson, and Fine-Gray competing risks regression are supported. This work was sponsored by NASA Grants 80NSSC19M0161 and 80NSSC23M0129 through a subcontract from the National Council on Radiation Protection and Measurements (NCRP). The computing for this project was performed on the Beocat Research Cluster at Kansas State University, which is funded in part by NSF grants CNS-1006860, EPS-1006860, EPS-0919443, ACI-1440548, CHE-1726332, and NIH P20GM113109.

Retorna detalhes de dados de CEPs brasileiros, bairros, logradouros e tal. (Returns info of Brazilian postal codes, city names, addresses and so on.).

Estimation, prediction, and simulation of nonstationary Gaussian process with modular covariate-based covariance functions. Sources of nonstationarity, such as spatial mean, variance, geometric anisotropy, smoothness, and nugget, can be considered based on spatial characteristics. An induced compact-supported nonstationary covariance function is provided, enabling fast and memory-efficient computations when handling densely sampled domains.