This package provides a large number of measurements generate count data. This is a statistical data type that only assumes non-negative integer values and is generated by counting. Typically, counting data can be found in biomedical applications, such as the analysis of DNA double-strand breaks. The number of DNA double-strand breaks can be counted in individual cells using various bioanalytical methods. For diagnostic applications, it is relevant to record the distribution of the number data in order to determine their biomedical significance (Roediger, S. et al., 2018. Journal of Laboratory and Precision Medicine. <doi:10.21037/jlpm.2018.04.10>). The software offers functions for a comprehensive automated evaluation of distribution models of count data. In addition to programmatic interaction, a graphical user interface (web server) is included, which enables fast and interactive data-scientific analyses. The user is supported in selecting the most suitable counting distribution for his own data set.

Direct sparse covariance matrix estimation via the covariance graphical lasso by Bien, Tibshirani (2011) <doi:10.1093/biomet/asr054> using the fast coordinate descent algorithm of Wang (2014) <doi:10.1007/s11222-013-9385-5>.

Estimates sugar beet canopy closure with remotely sensed leaf area index and estimates when action might be needed to protect the crop from a Leaf Spot epidemic with a negative prognosis model based on published models.

Calculate the R-squared, aka explained randomness, based on the partial likelihood ratio statistic under the Cox Proportional Hazard model [J O'Quigley, R Xu, J Stare (2005) <doi:10.1002/sim.1946>].

This package contains the prepared data that is needed for the shiny application examples in the canvasXpress package. This package also includes datasets used for automated testthat tests. Scotto L, Narayan G, Nandula SV, Arias-Pulido H et al. (2008) <doi:10.1002/gcc.20577>. Davis S, Meltzer PS (2007) <doi:10.1093/bioinformatics/btm254>.

Computing elliptical joint confidence regions at a specified confidence level. It provides the flexibility to estimate either classical or robust confidence regions, which can be visualized in 2D or 3D plots. The classical approach assumes normality and uses the mean and covariance matrix to define the confidence regions. Alternatively, the robustified version employs estimators like minimum covariance determinant (MCD) and M-estimator, making them less sensitive to outliers and departures from normality. Furthermore, the functions allow users to group the dataset based on categorical variables and estimate separate confidence regions for each group. This capability is particularly useful for exploring potential differences or similarities across subgroups within a dataset. Varmuza and Filzmoser (2009, ISBN:978-1-4200-5947-2). Johnson and Wichern (2007, ISBN:0-13-187715-1). Raymaekers and Rousseeuw (2019) <DOI:10.1080/00401706.2019.1677270>.

It computes full conformal, split conformal and multi split conformal prediction regions when the response has functional nature. Moreover, the package also contain a plot function to visualize the output of the split conformal. To guarantee consistency, the package structure mimics the univariate conformalInference package of professor Ryan Tibshirani. The main references for the code are: Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2102.06746>, Diquigiovanni, Fontana, and Vantini (2021) <arXiv:2106.01792>, Solari, and Djordjilovic (2021) <arXiv:2103.00627>.

Use the US Census API to collect summary data tables for SF1 and ACS datasets at arbitrary geographies.

This package provides automated small-cell suppression for one- and two-way frequency tables. Cells falling below a user-defined frequency threshold are masked, with suppression propagated to secondary cells to prevent indirect disclosure. Designed for clinical and health administrative data, the package supports a range of tabular structures and fits into reproducible reporting pipelines, reducing manual review while applying consistent suppression rules across data sharing workflows.

The Certifiably Optimal RulE ListS (Corels) learner by Angelino et al described in <doi:10.48550/arXiv.1704.01701> provides interpretable decision rules with an optimality guarantee, and is made available to R with this package. See the file AUTHORS for a list of copyright holders and contributors.

Unified access to carbon market data from compliance emissions trading systems ('EU ETS', UK ETS', RGGI', California Cap-and-Trade) and voluntary carbon markets (Verra, Gold Standard, American Carbon Registry, Climate Action Reserve, via the Berkeley Voluntary Registry Offsets Database and the CarbonPlan OffsetsDB API). Includes cross-market price data from the International Carbon Action Partnership ('ICAP') Allowance Price Explorer <https://icapcarbonaction.com/en/ets-prices>, global carbon pricing from the World Bank Carbon Pricing Dashboard <https://carbonpricingdashboard.worldbank.org/>, and the historical RFF World Carbon Pricing Database following Dolphin, Pollitt and Newbery (2020) <doi:10.1038/s41597-022-01659-x>. Data is downloaded from public sources on first use and cached locally.

This package provides an alternative approach to multiple testing by calculating a simultaneous upper confidence bounds for the number of true null hypotheses among any subset of the hypotheses of interest, using the methods of Goeman and Solari (2011) <doi:10.1214/11-STS356>.

Browser cookies are name-value pairs that are saved in a user's browser by a website. Cookies allow websites to persist information about the user and their use of the website. Here we provide tools for working with cookies in shiny apps, in part by wrapping the js-cookie JavaScript library <https://github.com/js-cookie/js-cookie>.

An R implementation of the algorithms described in Reingold and Dershowitz (4th ed., Cambridge University Press, 2018) <doi:10.1017/9781107415058>, allowing conversion between many different calendar systems. Cultural and religious holidays from several calendars can be calculated.

Proposed by Harrell, the C index or concordance C, is considered an overall measure of discrimination in survival analysis between a survival outcome that is possibly right censored and a predictive-score variable, which can represent a measured biomarker or a composite-score output from an algorithm that combines multiple biomarkers. This package aims to statistically compare two C indices with right-censored survival outcome, which commonly arise from a paired design and thus resulting two correlated C indices.

Reduction-based techniques for cost-sensitive multi-class classification, in which each observation has a different cost for classifying it into one class, and the goal is to predict the class with the minimum expected cost for each new observation. Implements Weighted All-Pairs (Beygelzimer, A., Langford, J., & Zadrozny, B., 2008, <doi:10.1007/978-0-387-79361-0_1>), Weighted One-Vs-Rest (Beygelzimer, A., Dani, V., Hayes, T., Langford, J., & Zadrozny, B., 2005, <https://dl.acm.org/citation.cfm?id=1102358>) and Regression One-Vs-Rest. Works with arbitrary classifiers taking observation weights, or with regressors. Also implements cost-proportionate rejection sampling for working with classifiers that don't accept observation weights.

Enables DBI compliant packages to integrate with the RStudio connections pane, and the pins package. It automates the display of schemata, tables, views, as well as the preview of the table's top 1000 records.

Decorate functions to make them return enhanced output. The enhanced output consists in an object of type chronicle containing the result of the function applied to its arguments, as well as a log detailing when the function was run, what were its inputs, what were the errors (if the function failed to run) and other useful information. Tools to handle decorated functions are included, such as a forward pipe operator that makes chaining decorated functions possible.

Features tools for exploring congruent phylogenetic birth-death models. It can construct the pulled speciation- and net-diversification rates from a reference model. Given alternative speciation- or extinction rates, it can construct new models that are congruent with the reference model. Functionality is included to sample new rate functions, and to visualize the distribution of one congruence class. See also Louca & Pennell (2020) <doi:10.1038/s41586-020-2176-1>.

Terrestrial maps with simplified topologies for Census Divisions, Agricultural Regions, Economic Regions, Federal Electoral Divisions and Provinces.

Enables simultaneous statistical inference for the accuracy of multiple classifiers in multiple subgroups (strata). For instance, allows to perform multiple comparisons in diagnostic accuracy studies with co-primary endpoints sensitivity and specificity (Westphal M, Zapf A. Statistical inference for diagnostic test accuracy studies with multiple comparisons. Statistical Methods in Medical Research. 2024;0(0). <doi:10.1177/09622802241236933>).

This package provides functions for loading large (10M+ lines) CSV and other delimited files, similar to read.csv, but typically faster and using less memory than the standard R loader. While not entirely general, it covers many common use cases when the types of columns in the CSV file are known in advance. In addition, the package provides a class int64', which represents 64-bit integers exactly when reading from a file. The latter is useful when working with 64-bit integer identifiers exported from databases. The CSV file loader supports common column types including integer', double', string', and int64', leaving further type transformations to the user.

Convert text into synthesized speech and get a list of supported voices for a region. Microsoft's Cognitive Services Text to Speech REST API <https://learn.microsoft.com/en-us/azure/cognitive-services/speech-service/rest-text-to-speech?tabs=streaming> supports neural text to speech voices, which support specific languages and dialects that are identified by locale.

This package provides a workflow to generate and analyze signatures based on copy number data using non-negative matrix factorization (NMF) in an approach similar to that used in mutational signatures. It can be used to extract features from Copy number segment data and use that to find a subset of copy number signatures which can be further used to correlate with other relevant data. For more on NMF see Gaujoux (2013) <doi:10.1186/1471-2105-11-367>.