This package provides a tool which aims to help evaluate the effect of external borrowing using an integrated approach described in Lewis et al., (2019) <doi:10.1080/19466315.2018.1497533> that combines propensity score and Bayesian dynamic borrowing methods.

To assist you with troubleshooting internet connection issues and assist in isolating packet loss on your network. It does this by allowing you to retrieve the top trace route destinations your internet provider uses, and recursively ping each server in series while capturing the results and writing them to a log file. Each iteration it queries the destinations again, before shuffling the sequence of destinations to ensure the analysis is unbiased and consistent across each trace route.

Simulate the dynamic of lion populations using a specific Individual-Based Model (IBM) compiled in C.

This package provides functions to generate ensembles of generalized linear models using a greedy projected subset gradient descent algorithm. The sparsity and diversity tuning parameters are selected by cross-validation.

This package provides a package for selecting the most relevant features (genes) in the high-dimensional binary classification problems. The discriminative features are identified using analyzing the overlap between the expression values across both classes. The package includes functions for measuring the proportional overlapping score for each gene avoiding the outliers effect. The used measure for the overlap is the one defined in the "Proportional Overlapping Score (POS)" technique for feature selection. A gene mask which represents a gene's classification power can also be produced for each gene (feature). The set size of the selected genes might be set by the user. The minimum set of genes that correctly classify the maximum number of the given tissue samples (observations) can be also produced.

This package provides methods for building self-organizing maps (SOMs) with a number of distinguishing features such automatic centroid detection and cluster visualization using starbursts. For more details see the paper "Improved Interpretability of the Unified Distance Matrix with Connected Components" by Hamel and Brown (2011) in <ISBN:1-60132-168-6>. The package provides user-friendly access to two models we construct: (a) a SOM model and (b) a centroid based clustering model. The package also exposes a number of quality metrics for the quantitative evaluation of the map, Hamel (2016) <doi:10.1007/978-3-319-28518-4_4>. Finally, we reintroduced our fast, vectorized training algorithm for SOM with substantial improvements. It is about an order of magnitude faster than the canonical, stochastic C implementation <doi:10.1007/978-3-030-01057-7_60>.

This package implements data processing described in <doi:10.1126/sciadv.abk3283> to align modern differentially private data with formatting of older US Census data releases. The primary goal is to read in Census Privacy Protected Microdata Files data in a reproducible way. This includes tools for aggregating to relevant levels of geography by creating geographic identifiers which match the US Census Bureau's numbering. Additionally, there are tools for grouping race numeric identifiers into categories, consistent with OMB (Office of Management and Budget) classifications. Functions exist for downloading and linking to existing sources of privacy protected microdata.

Computes the D', Wn, and conditional asymmetric linkage disequilibrium (ALD) measures for pairs of genetic loci. Performs these linkage disequilibrium (LD) calculations on phased genotype data recorded using Genotype List (GL) String or columnar formats. Alternatively, generates expectation-maximization (EM) estimated haplotypes from phased data, or performs LD calculations on EM estimated haplotypes. Performs sign tests comparing LD values for phased and unphased datasets, and generates heat-maps for each LD measure. Described by Osoegawa et al. (2019a) <doi:10.1016/j.humimm.2019.01.010>, and Osoegawa et. al. (2019b) <doi:10.1016/j.humimm.2019.05.018>.

This is a data-only package, containing data needed to run the CRAN package pathfindR', a package for enrichment analysis utilizing active subnetworks. This package contains protein-protein interaction network data, data related to gene sets and example input/output data.

An extensible repository of accurate, up-to-date functions to score commonly used patient-reported outcome (PRO), quality of life (QOL), and other psychometric and psychological measures. PROscorer', together with the PROscorerTools package, is a system to facilitate the incorporation of PRO measures into research studies and clinical settings in a scientifically rigorous and reproducible manner. These packages and their vignettes are intended to help establish and promote best practices for scoring PRO and PRO-like measures in research. The PROscorer Instrument Descriptions vignette contains descriptions of each instrument scored by PROscorer', complete with references. These instrument descriptions are suitable for inclusion in formal study protocol documents, grant proposals, and manuscript Method sections. Each PROscorer function is composed of helper functions from the PROscorerTools package, and users are encouraged to contribute new functions to PROscorer'. More scoring functions are currently in development and will be added in future updates.

Calculate POTH for treatment hierarchies from frequentist and Bayesian network meta-analysis. POTH quantifies the certainty in a treatment hierarchy. Subset POTH, POTH residuals, and best k treatments POTH can also be calculated to improve interpretation of treatment hierarchies.

Automatic estimation of number of principal components in PCA with PEnalized SEmi-integrated Likelihood (PESEL). See Piotr Sobczyk, Malgorzata Bogdan, Julie Josse "Bayesian dimensionality reduction with PCA using penalized semi-integrated likelihood" (2017) <doi:10.1080/10618600.2017.1340302>.

Collection of functions to get files in parquet format. Parquet is a columnar storage file format <https://parquet.apache.org/>. The files to convert can be of several formats ("csv", "RData", "rds", "RSQLite", "json", "ndjson", "SAS", "SPSS"...).

The pedsuite is a collection of packages for pedigree analysis, covering applications in forensic genetics, medical genetics and more. A detailed presentation of the pedsuite is given in the book Pedigree Analysis in R (Vigeland, 2021, ISBN: 9780128244302).

This package provides a bunch of convenience functions that transform the results of some basic statistical analyses into table format nearly ready for publication. This includes descriptive tables, tables of logistic regression and Cox regression results as well as forest plots.

Like similar profiling tools, the proffer package automatically detects sources of slowness in R code. The distinguishing feature of proffer is its utilization of pprof', which supplies interactive visualizations that are efficient and easy to interpret. Behind the scenes, the profile package converts native Rprof() data to a protocol buffer that pprof understands. For the documentation of proffer', visit <https://r-prof.github.io/proffer/>. To learn about the implementations and methodologies of pprof', profile', and protocol buffers, visit <https://github.com/google/pprof>. <https://protobuf.dev>, and <https://github.com/r-prof/profile>, respectively.

Fits successive Lasso models for several blocks of (omics) data with different priorities and takes the predicted values as an offset for the next block. Also offers options to deal with block-wise missingness in multi-omics data.

The R package povmap supports small area estimation of means and poverty headcount rates. It adds several new features to the emdi package (see "The R Package emdi for Estimating and Mapping Regionally Disaggregated Indicators" by Kreutzmann et al. (2019) <doi:10.18637/jss.v091.i07>). These include new options for incorporating survey weights, ex-post benchmarking of estimates, two additional transformations, several new convenient functions to assist with reporting results, and a wrapper function to facilitate access from Stata'.

Preprocess numeric data matrices into desired transformed representations. Standardization, Unitization, Cubitization and adaptive intervals are offered.

Estimation of panel models for glm-like models: this includes binomial models (logit and probit), count models (poisson and negbin) and ordered models (logit and probit), as described in: Baltagi (2013) Econometric Analysis of Panel Data, ISBN-13:978-1-118-67232-7, Hsiao (2014) Analysis of Panel Data <doi:10.1017/CBO9781139839327> and Croissant and Millo (2018), Panel Data Econometrics with R, ISBN:978-1-118-94918-4.

Useful functions and workflows for proteomics quality control and data analysis of both limited proteolysis-coupled mass spectrometry (LiP-MS) (Feng et. al. (2014) <doi:10.1038/nbt.2999>) and regular bottom-up proteomics experiments. Data generated with search tools such as Spectronaut', MaxQuant and Proteome Discover can be easily used due to flexibility of functions.

This package implements statistical methods for estimating disease penetrance in family-based studies. Penetrance refers to the probability of disease§ manifestation in individuals carrying specific genetic variants. The package provides tools for age-specific penetrance estimation, handling missing data, and accounting for ascertainment bias in family studies. Cite as: Kubista, N., Braun, D. & Parmigiani, G. (2024) <doi:10.48550/arXiv.2411.18816>.

Calculate the Bayesian posterior/predictive probability and determine the sample size and stopping boundaries for single-arm Phase II design.

Smoothing splines with penalties on order m derivatives.