This package implements a Markov Chain Monte Carlo algorithm to approximate exact conditional inference for logistic regression models. Exact conditional inference is based on the distribution of the sufficient statistics for the parameters of interest given the sufficient statistics for the remaining nuisance parameters. Using model formula notation, users specify a logistic model and model terms of interest for exact inference. See Zamar et al. (2007) <doi:10.18637/jss.v021.i03> for more details.

This package provides a set of extensions for the ergm package to fit multilayer/multiplex/multirelational networks and samples of multiple networks. ergm.multi is a part of the Statnet suite of packages for network analysis. See Krivitsky, Koehly, and Marcum (2020) <doi:10.1007/s11336-020-09720-7> and Krivitsky, Coletti, and Hens (2023) <doi:10.1080/01621459.2023.2242627>.

This package implements a segmentation algorithm for multiple change-point detection in univariate time series using the Ensemble Binary Segmentation of Korkas (2022) <Journal of the Korean Statistical Society, 51(1), pp.65-86.>.

This package provides functions for signal detection and identification designed for Event-Related Potentials (ERP) data in a linear model framework. The functional F-test proposed in Causeur, Sheu, Perthame, Rufini (2018, submitted) for analysis of variance issues in ERP designs is implemented for signal detection (tests for mean difference among groups of curves in One-way ANOVA designs for example). Once an experimental effect is declared significant, identification of significant intervals is achieved by the multiple testing procedures reviewed and compared in Sheu, Perthame, Lee and Causeur (2016, <DOI:10.1214/15-AOAS888>). Some of the methods gathered in the package are the classical FDR- and FWER-controlling procedures, also available using function p.adjust. The package also implements the Guthrie-Buchwald procedure (Guthrie and Buchwald, 1991 <DOI:10.1111/j.1469-8986.1991.tb00417.x>), which accounts for the auto-correlation among t-tests to control erroneous detection of short intervals. The Adaptive Factor-Adjustment method is an extension of the method described in Causeur, Chu, Hsieh and Sheu (2012, <DOI:10.3758/s13428-012-0230-0>). It assumes a factor model for the correlation among tests and combines adaptively the estimation of the signal and the updating of the dependence modelling (see Sheu et al., 2016, <DOI:10.1214/15-AOAS888> for further details).

This is a package for exact Confidence Intervals for the difference between two independent or dependent proportions.

This package implements the Ebrahim-Farrington goodness-of-fit test for logistic regression models, particularly effective for sparse data and binary outcomes. This test provides an improved alternative to the traditional Hosmer-Lemeshow test by using a modified Pearson chi-square statistic with data-dependent grouping. The test is based on Farrington (1996) theoretical framework but simplified for practical implementation with binary data. Includes functions for both the original Farrington test (for grouped data) and the new Ebrahim-Farrington test (for binary data with automatic grouping). For more details see Hosmer (1980) <doi:10.1080/03610928008827941> and Farrington (1996) <doi:10.1111/j.2517-6161.1996.tb02086.x>.

Datasets from Nelson, Coffin and Copeland "Introductory Statistics for Engineering Experimentation" (Elsevier, 2003) with sample code.

This package contains two functions that are intended to make tuning supervised learning methods easy. The eztune function uses a genetic algorithm or Hooke-Jeeves optimizer to find the best set of tuning parameters. The user can choose the optimizer, the learning method, and if optimization will be based on accuracy obtained through validation error, cross validation, or resubstitution. The function eztune.cv will compute a cross validated error rate. The purpose of eztune_cv is to provide a cross validated accuracy or MSE when resubstitution or validation data are used for optimization because error measures from both approaches can be misleading.

Bayesian estimation of spatial weight matrices in spatial econometric panel models. Allows for estimation of spatial autoregressive (SAR), spatial error (SEM), spatial Durbin (SDM), spatial error Durbin (SDEM) and spatially lagged explanatory variable (SLX) type specifications featuring an unknown spatial weight matrix. Methodological details are given in Krisztin and Piribauer (2022) <doi:10.1080/17421772.2022.2095426>.

Create causal models for use in epidemiological studies, including sufficient-component cause models as introduced by Rothman (1976) <doi:10.1093/oxfordjournals.aje.a112335>.

Experiences studies are an integral component of the actuarial control cycle. Regardless of the decrement or policyholder behavior of interest, the analyses conducted is often the same. Ultimately, this package aims to reduce time spent writing the same code used for different experience studies, therefore increasing the time for to uncover new insights inherit within the relevant experience.

Standardises and facilitates the use of eleven established stability properties that have been used to assess systemsâ responses to press or pulse disturbances at different ecological levels (e.g. population, community). There are two sets of functions. The first set corresponds to functions that measure stability at any level of organisation, from individual to community and can be applied to a time series of a systemâ s state variables (e.g., body mass, population abundance, or species diversity). The properties included in this set are: invariability, resistance, extent and rate of recovery, persistence, and overall ecological vulnerability. The second set of functions can be applied to Jacobian matrices. The functions in this set measure the stability of a community at short and long time scales. In the short term, the communityâ s response is measured by maximal amplification, reactivity and initial resilience (i.e. initial rate of return to equilibrium). In the long term, stability can be measured as asymptotic resilience and intrinsic stochastic invariability. Figueiredo et al. (2025) <doi:10.32942/X2M053>.

Implementation of the Edge Selection Algorithm for undirected graph selection. The least angle regression-based algorithm selects edges of an undirected graph based on the projection of the current residuals on the two dimensional edge-planes. The algorithm selects symmetric adjacency matrix, which many other regression-based undirected graph selection procedures cannot do.

An integrated set of tools to analyze and simulate networks based on exponential-family random graph models (ERGMs). ergm is a part of the Statnet suite of packages for network analysis. See Hunter, Handcock, Butts, Goodreau, and Morris (2008) <doi:10.18637/jss.v024.i03> and Krivitsky, Hunter, Morris, and Klumb (2023) <doi:10.18637/jss.v105.i06>.

Presents a statistical method that uses a recursive algorithm for signal extraction. The method handles a non-parametric estimation for the correlation of the errors. See "Krivobokova", "Serra", "Rosales" and "Klockmann" (2021) <arXiv:1812.06948> for details.

An implementation of a variety of escalation with overdose control designs introduced by Babb, Rogatko and Zacks (1998) <doi:10.1002/(SICI)1097-0258(19980530)17:10%3C1103::AID-SIM793%3E3.0.CO;2-9>. It calculates the next dose as a clinical trial proceeds and performs simulations to obtain operating characteristics.

Maximum likelihood estimation of an extended class of row-column (RC) association models for two-dimensional contingency tables, which are formulated by a condition of reduced rank on a matrix of extended association parameters; see Forcina (2019) <arXiv:1910.13848>. These parameters are defined by choosing the logit type for the row and column variables among four different options and a transformation derived from suitable divergence measures.

An R interface to United States Environmental Protection Agency (EPA) Environmental Compliance History Online ('ECHO') Application Program Interface (API). ECHO provides information about EPA permitted facilities, discharges, and other reporting info associated with permitted entities. Data are obtained from <https://echo.epa.gov/>.

Process and analyze electronic health record (EHR) data. The EHR package provides modules to perform diverse medication-related studies using data from EHR databases. Especially, the package includes modules to perform pharmacokinetic/pharmacodynamic (PK/PD) analyses using EHRs, as outlined in Choi, Beck, McNeer, Weeks, Williams, James, Niu, Abou-Khalil, Birdwell, Roden, Stein, Bejan, Denny, and Van Driest (2020) <doi:10.1002/cpt.1787>. Additional modules will be added in future. In addition, this package provides various functions useful to perform Phenome Wide Association Study (PheWAS) to explore associations between drug exposure and phenotypes obtained from EHR data, as outlined in Choi, Carroll, Beck, Mosley, Roden, Denny, and Van Driest (2018) <doi:10.1093/bioinformatics/bty306>.

This package provides tools for integrated sensitivity analysis of evidence factors in observational studies. When an observational study allows for multiple independent or nearly independent inferences which, if vulnerable, are vulnerable to different biases, we have multiple evidence factors. This package provides methods that respect type I error rate control. Examples are provided of integrated evidence factors analysis in a longitudinal study with continuous outcome and in a case-control study. Karmakar, B., French, B., and Small, D. S. (2019)<DOI:10.1093/biomet/asz003>.

The algorithm of semi-supervised learning based on finite Gaussian mixture models with a missing-data mechanism is designed for a fitting g-class Gaussian mixture model via maximum likelihood (ML). It is proposed to treat the labels of the unclassified features as missing-data and to introduce a framework for their missing as in the pioneering work of Rubin (1976) for missing in incomplete data analysis. This dependency in the missingness pattern can be leveraged to provide additional information about the optimal classifier as specified by Bayesâ rule.

This package provides a toolset for generating Ecological Limit Function (ELF) models and evaluating potential species loss resulting from flow change, based on the elfgen framework. ELFs describe the relation between aquatic species richness (fish or benthic macroinvertebrates) and stream size characteristics (streamflow or drainage area). Journal publications are available outlining framework methodology (Kleiner et al. (2020) <doi:10.1111/1752-1688.12876>) and application (Rapp et al. (2020) <doi:10.1111/1752-1688.12877>).

Four ensemble-based methods (SMOTEBoost, RUSBoost, UnderBagging, and SMOTEBagging) for class imbalance problem are implemented for binary classification. Such methods adopt ensemble methods and data re-sampling techniques to improve model performance in presence of class imbalance problem. One special feature offers the possibility to choose multiple supervised learning algorithms to build weak learners within ensemble models. References: Nitesh V. Chawla, Aleksandar Lazarevic, Lawrence O. Hall, and Kevin W. Bowyer (2003) <doi:10.1007/978-3-540-39804-2_12>, Chris Seiffert, Taghi M. Khoshgoftaar, Jason Van Hulse, and Amri Napolitano (2010) <doi:10.1109/TSMCA.2009.2029559>, R. Barandela, J. S. Sanchez, R. M. Valdovinos (2003) <doi:10.1007/s10044-003-0192-z>, Shuo Wang and Xin Yao (2009) <doi:10.1109/CIDM.2009.4938667>, Yoav Freund and Robert E. Schapire (1997) <doi:10.1006/jcss.1997.1504>.

Calculates the empirical likelihood ratio and p-value for a mean-type hypothesis (or multiple mean-type hypotheses) based on two samples with possible censored data.