Proposes a torch implementation of Graph Net architecture allowing different options for message passing and feature embedding.

Estimate the regression coefficients and the baseline hazard of proportional hazard Cox models with left, right or interval censored survival data using maximum penalised likelihood. A non-parametric smooth estimate of the baseline hazard function is provided.

Easily create alerts, notifications, modals, info tips and loading screens in Shiny'. Includes several options to customize alerts and notifications by including text, icons, images and buttons. When wrapped around a Shiny output, loading screen is automatically displayed while the output is being recalculated.

Implementation of the SRCS method for a color-based visualization of the results of multiple pairwise tests on a large number of problem configurations, proposed in: I.G. del Amo, D.A. Pelta. SRCS: a technique for comparing multiple algorithms under several factors in dynamic optimization problems. In: E. Alba, A. Nakib, P. Siarry (Eds.), Metaheuristics for Dynamic Optimization. Series: Studies in Computational Intelligence 433, Springer, Berlin/Heidelberg, 2012.

This package provides drop-in replacements for functions from the stringr package, with the same user interface. These functions have no external dependencies and can be copied directly into your package code using the staticimports package.

This package provides a customizable timer widget for shiny applications. Key features include countdown and count-up mode, multiple display formats (including simple seconds, minutes-seconds, hours-minutes-seconds, and minutes-seconds-centiseconds), ability to pause, resume, and reset the timer. shinytimer widget can be particularly useful for creating interactive and time-sensitive applications, tracking session times, setting time limits for tasks or quizzes, and more.

This statistical method uses the nearest neighbor algorithm to estimate absolute distances between single cells based on a chosen constellation of surface proteins, with these distances being a measure of the similarity between the two cells being compared. Based on Sen, N., Mukherjee, G., and Arvin, A.M. (2015) <DOI:10.1016/j.ymeth.2015.07.008>.

Implement K-nearest neighbor classifier, weighted nearest neighbor classifier, bagged nearest neighbor classifier, optimal weighted nearest neighbor classifier and stabilized nearest neighbor classifier, and perform model selection via 5 fold cross-validation for them. This package also provides functions for computing the classification error and classification instability of a classification procedure.

Taxonomic dictionaries, formative element lists, and functions related to the maintenance, development and application of U.S. Soil Taxonomy. Data and functionality are based on official U.S. Department of Agriculture sources including the latest edition of the Keys to Soil Taxonomy. Descriptions and metadata are obtained from the National Soil Information System or Soil Survey Geographic databases. Other sources are referenced in the data documentation. Provides tools for understanding and interacting with concepts in the U.S. Soil Taxonomic System. Most of the current utilities are for working with taxonomic concepts at the "higher" taxonomic levels: Order, Suborder, Great Group, and Subgroup.

Supplementary functions for item response models aiming to complement existing R packages. The functionality includes among others multidimensional compensatory and noncompensatory IRT models (Reckase, 2009, <doi:10.1007/978-0-387-89976-3>), MCMC for hierarchical IRT models and testlet models (Fox, 2010, <doi:10.1007/978-1-4419-0742-4>), NOHARM (McDonald, 1982, <doi:10.1177/014662168200600402>), Rasch copula model (Braeken, 2011, <doi:10.1007/s11336-010-9190-4>; Schroeders, Robitzsch & Schipolowski, 2014, <doi:10.1111/jedm.12054>), faceted and hierarchical rater models (DeCarlo, Kim & Johnson, 2011, <doi:10.1111/j.1745-3984.2011.00143.x>), ordinal IRT model (ISOP; Scheiblechner, 1995, <doi:10.1007/BF02301417>), DETECT statistic (Stout, Habing, Douglas & Kim, 1996, <doi:10.1177/014662169602000403>), local structural equation modeling (LSEM; Hildebrandt, Luedtke, Robitzsch, Sommer & Wilhelm, 2016, <doi:10.1080/00273171.2016.1142856>).

S4 class object for creating and managing group sequential designs. It calculates the efficacy and futility boundaries at each look. It allows modifying the design and tracking the design update history.

Perform a probabilistic linkage of two data files using a scaling procedure using the methods described in Goldstein, H., Harron, K. and Cortina-Borja, M. (2017) <doi:10.1002/sim.7287>.

This package implements Additive Logistic Transformation (alr) for Small Area Estimation under Fay Herriot Model. Small Area Estimation is used to borrow strength from auxiliary variables to improve the effectiveness of a domain sample size. This package uses Empirical Best Linear Unbiased Prediction (EBLUP). The Additive Logistic Transformation (alr) are based on transformation by Aitchison J (1986). The covariance matrix for multivariate application is based on covariance matrix used by Esteban M, Lombardà a M, López-Vizcaà no E, Morales D, and Pérez A <doi:10.1007/s11749-019-00688-w>. The non-sampled models are modified area-level models based on models proposed by Anisa R, Kurnia A, and Indahwati I <doi:10.9790/5728-10121519>, with univariate model using model-3, and multivariate model using model-1. The MSE are estimated using Parametric Bootstrap approach. For non-sampled cases, MSE are estimated using modified approach proposed by Haris F and Ubaidillah A <doi:10.4108/eai.2-8-2019.2290339>.

This package provides a subgroup identification method for precision medicine based on quantitative objectives. This method can handle continuous, binary and survival endpoint for both prognostic and predictive case. For the predictive case, the method aims at identifying a subgroup for which treatment is better than control by at least a pre-specified or auto-selected constant. For the prognostic case, the method aims at identifying a subgroup that is at least better than a pre-specified/auto-selected constant. The derived signature is a linear combination of predictors, and the selected subgroup are subjects with the signature > 0. The false discover rate when no true subgroup exists is controlled at a user-specified level.

This package provides a computing tool is developed to automated identify somatic mutation-driven immune cells. The operation modes including: i) inferring the relative abundance matrix of tumor-infiltrating immune cells and integrating it with a particular gene mutation status, ii) detecting differential immune cells with respect to the gene mutation status and converting the abundance matrix of significant differential immune cell into two binary matrices (one for up-regulated and one for down-regulated), iii) identifying somatic mutation-driven immune cells by comparing the gene mutation status with each immune cell in the binary matrices across all samples, and iv) visualization of immune cell abundance of samples in different mutation status..

Load and export SomaScan data via the SomaLogic Operating Co., Inc. structured text file called an ADAT ('*.adat'). For file format see <https://github.com/SomaLogic/SomaLogic-Data/blob/main/README.md>. The package also exports auxiliary functions for manipulating, wrangling, and extracting relevant information from an ADAT object once in memory.

Landsat satellites collect important data about global forest conditions. Documentation about Landsat's role in forest disturbance estimation is available at the site <https://landsat.gsfc.nasa.gov/>. By constrained quadratic B-splines, this package delivers an optimal shape-restricted trajectory to a time series of Landsat imagery for the purpose of modeling annual forest disturbance dynamics to behave in an ecologically sensible manner assuming one of seven possible "shapes", namely, flat, decreasing, one-jump (decreasing, jump up, decreasing), inverted vee (increasing then decreasing), vee (decreasing then increasing), linear increasing, and double-jump (decreasing, jump up, decreasing, jump up, decreasing). The main routine selects the best shape according to the minimum Bayes information criterion (BIC) or the cone information criterion (CIC), which is defined as the log of the estimated predictive squared error. The package also provides parameters summarizing the temporal pattern including year(s) of inflection, magnitude of change, pre- and post-inflection rates of growth or recovery. In addition, it contains routines for converting a flat map of disturbance agents to time-series disturbance maps and a graphical routine displaying the fitted trajectory of Landsat imagery.

Algorithms for the implementation and evaluation of Monte Carlo tests, as well as for their use in multiple testing procedures.

Send email using Sendgrid <https://sendgrid.com/> mail API(v3) <https://docs.sendgrid.com/api-reference/how-to-use-the-sendgrid-v3-api/authentication>.

This package provides a programmatic interface to many species occurrence data sources, including Global Biodiversity Information Facility ('GBIF'), iNaturalist', eBird', Integrated Digitized Biocollections ('iDigBio'), VertNet', Ocean Biogeographic Information System ('OBIS'), and Atlas of Living Australia ('ALA'). Includes functionality for retrieving species occurrence data, and combining those data.

Use R to interface with the Charles Schwab Trade API <https://developer.schwab.com/>. Functions include authentication, trading, price requests, account information, and option chains. A user will need a Schwab brokerage account and Schwab Individual Developer app. See README for authentication process and examples.

Data sets and code blocks for the book Statistical Analysis of Network Data with R, 2nd Edition'.

Spatial transcriptomics iterative hierarchical clustering ('stIHC'), is a method for identifying spatial gene co-expression modules, defined as groups of genes with shared spatial expression patterns. The method is applicable across spatial transcriptomics technologies with differing spatial resolution, and provides a framework for investigating the spatial organisation of gene expression in tissues. For further details, see Higgins C., Li J.J., Carey M. <doi:10.1002/qub2.70011>.

This package provides a framework for evaluation of clinical trial safety. Users can interactively explore their data using the included Shiny application.