This package provides an electrophysiological data analysis library for Python.

PyNWB is a Python package for working with NWB files. It provides a high-level API for efficiently working with Neurodata stored in the NWB format.

A simple python package for fitting L2- and smoothing-penalized generalized linear models. Built primarily because the statsmodels GLM fit_regularized method is built to do elastic net (combination of L1 and L2 penalities), but if you just want to do an L2 or a smoothing penalty (like in generalized additive models), using a penalized iteratively reweighted least squares (p-IRLS) is much faster.

spike sorting pipeline.

This is a Python package for performing representational similarity analysis (RSA) using MNE-Python data structures. The main use-case is to perform RSA using a “searchlight” approach through time and/or a volumetric or surface source space.

This inspector is meant as a companion to the PyNWB validator, which checks for strict schema compliance. This tool attempts to apply some common sense to find components of the file that are technically compliant, but possibly incorrect, suboptimal in their representation, or deviate from best practices.

pyRiemann is a Python machine learning package based on scikit-learn API. It provides a high-level interface for processing and classification of real (resp. complex)-valued multivariate data through the Riemannian geometry of symmetric (resp. Hermitian) positive definite (SPD) (resp. HPD) matrices.

Neo is a package for representing electrophysiology data in Python, together with support for reading a wide range of neurophysiology file formats.

Picard provides Python/Octave/MATLAB code for the preconditionned ICA for real data.

This is an open-source tool which allows to load CURRY data into Python. It supports: raw float (.cdt), ascii (.cdt), legacy raw float (.dat) and legacy ascii (.dat).

SpikeInterface is a Python framework designed to unify preexisting spike sorting technologies into a single code base.

It can:

• read/write many extracellular file formats.

• pre-process extracellular recordings.

• run many popular, semi-automatic spike sorters (kilosort1-4, mountainsort4-5, spykingcircus, tridesclous, ironclust, herdingspikes, yass, waveclus)

• run sorters developed in house (lupin, spkykingcicus2, tridesclous2, simple) that compete with kilosort4

• run theses polar sorters without installation using containers (Docker/Singularity).

• post-process sorted datasets using th SortingAnalyzer

• compare and benchmark spike sorting outputs.

• compute quality metrics to validate and curate spike sorting outputs.

• visualize recordings and spike sorting outputs in several ways (matplotlib, sortingview, jupyter, ephyviewer)

• export a report and/or export to phy

• curate your sorting with several strategies (ml-based, metrics based, manual, ...)

• have powerful sorting components to build your own sorter.

• have a full motion/drift correction framework.

replay_trajectory_classification is a Python package for decoding spatial position represented by neural activity and categorizing the type of trajectory.

It has several advantages over decoders typically used to characterize hippocampal data:

• It allows for moment-by-moment estimation of position using small temporal time bins which allow for rapid movement of neural position and makes fewer assumptions about what downstream cells can integrate.

• The decoded trajectories can change direction and are not restricted to constant velocity trajectories.

• The decoder can use spikes from spike-sorted cells or use clusterless spikes and their associated waveform features to decode.

• The decoder can categorize the type of neural trajectory and give an estimate of the confidence of the model in the type of trajectory.

• Proper handling of complex 1D linearized environments.

• Ability to extract and decode 2D environments.

• Easily installable, documented code with tutorials on how to use the code.

• Fast computation using GPUs.

This package implements both parametric and permutation-based ARI, and is meant to be compatible with the MNE-Python ecosystem.

bycycle is a tool for quantifying features of neural oscillations in the time domain, as opposed to the frequency domain, using a cycle-by-cycle approach.

Meggie is an open-source software designed for intuitive MEG and EEG analysis. With its user-friendly graphical interface, Meggie brings the powerful analysis methods of MNE-Python to researchers without requiring programming skills.

This package provides a Python implementation of a multitaper window method for estimating Wigner spectra for certain locally stationary processes.

This package provides a C++ library for multi-modal time-synched data transmission over the local network.

This package provides a simple open source Python package for EEG microstate segmentation.

This package provides tools for finding sharp-wave ripple events (150-250 Hz) from local field potentials.

This package provides tools for calculating smoothed 2D position, speed, head direction.

YASA is a Python package to analyze polysomnographic sleep recordings.

MNE-Python is an open-source Python package for exploring, visualizing, and analyzing human neurophysiological data such as MEG, EEG, sEEG, ECoG, and more. It includes modules for data input/output, preprocessing, visualization, source estimation, time-frequency analysis, connectivity analysis, machine learning, statistics, and more.

This is a library to automatically reject bad trials and repair bad sensors in magneto-/electroencephalography (M/EEG) data.

XDF is a general-purpose container format for multi-channel time series data with extensive associated meta information. XDF is tailored towards biosignal data such as EEG, EMG, EOG, ECG, GSR, MEG, but it can also handle data with high sampling rate (like audio) or data with a high number of channels (like fMRI or raw video). Meta information is stored as XML.