Simplifies the execution of command line interface (CLI) tools within isolated and reproducible environments. It enables users to effortlessly manage Conda environments, execute command line tools, handle dependencies, and ensure reproducibility in their data analysis workflows.

Supplies higher-order coordinatized data specification and fluid transform operators that include pivot and anti-pivot as special cases. The methodology is describe in Zumel', 2018, "Fluid data reshaping with cdata'", <https://winvector.github.io/FluidData/FluidDataReshapingWithCdata.html> , <DOI:10.5281/zenodo.1173299> . This package introduces the idea of explicit control table specification of data transforms. Works on in-memory data or on remote data using rquery and SQL database interfaces.

Simple interpolation methods designed to be used from C code. Supports constant, linear and spline interpolation. An R wrapper is included but this package is primarily designed to be used from C code using LinkingTo'. The spline calculations are classical cubic interpolation, e.g., Forsythe, Malcolm and Moler (1977) <ISBN: 9780131653320>.

Estimate coefficients of Cox proportional hazards model using stochastic gradient descent algorithm for batch data.

Estimation and goodness-of-fit functions for copula-based models of bivariate data with arbitrary distributions (discrete, continuous, mixture of both types). The copula families considered here are the Gaussian, Student, Clayton, Frank, Gumbel, Joe, Plackett, BB1, BB6, BB7,BB8, together with the following non-central squared copula families in Nasri (2020) <doi:10.1016/j.spl.2020.108704>: ncs-gaussian, ncs-clayton, ncs-gumbel, ncs-frank, ncs-joe, and ncs-plackett. For theoretical details, see, e.g., Nasri and Remillard (2023) <arXiv:2301.13408>.

Assignment of cell type labels to single-cell RNA sequencing (scRNA-seq) clusters is often a time-consuming process that involves manual inspection of the cluster marker genes complemented with a detailed literature search. This is especially challenging when unexpected or poorly described populations are present. The clustermole R package provides methods to query thousands of human and mouse cell identity markers sourced from a variety of databases.

This package provides functions for reading in and manipulating CRU TS3.21: Climatic Research Unit (CRU) Time-Series (TS) Version 3.21 data.

The currentSurvival package contains functions for the estimation of the current cumulative incidence (CCI) and the current leukaemia-free survival (CLFS). The CCI is the probability that a patient is alive and in any disease remission (e.g. complete cytogenetic remission in chronic myeloid leukaemia) after initiating his or her therapy (e.g. tyrosine kinase therapy for chronic myeloid leukaemia). The CLFS is the probability that a patient is alive and in any disease remission after achieving the first disease remission.

We propose a consistent monitoring procedure to detect a structural change from a cointegrating relationship to a spurious relationship. The procedure is based on residuals from modified least squares estimation, using either Fully Modified, Dynamic or Integrated Modified OLS. It is inspired by Chu et al. (1996) <DOI:10.2307/2171955> in that it is based on parameter estimation on a pre-break "calibration" period only, rather than being based on sequential estimation over the full sample. See the discussion paper <DOI:10.2139/ssrn.2624657> for further information. This package provides the monitoring procedures for both the cointegration and the stationarity case (while the latter is just a special case of the former one) as well as printing and plotting methods for a clear presentation of the results.

Detect and quantify community assembly processes using trait values of individuals or populations, the T-statistics and other metrics, and dedicated null models.

This package provides a set of common functions to be used for displaying messages, checking variables, finding absolute paths, starting applications, etc. More functions will be added later.

Solving the problem of project management using CPM (Critical Path Method), PERT (Program Evaluation and Review Technique) and LESS (Least Cost Estimating and Scheduling) methods. The package sets the critical path, schedule and Gantt chart. In addition, it allows to draw a graph even with marked critical activities. For more information about project management see: Taha H. A. "Operations Research. An Introduction" (2017, ISBN:978-1-292-16554-7), Rama Murthy P. "Operations Research" (2007, ISBN:978-81-224-2944-2), Yuval Cohen & Arik Sadeh (2006) "A New Approach for Constructing and Generating AOA Networks", Journal of Engineering, Computing and Architecture 1. 1-13, Konarzewska I., Jewczak M., Kucharski A. (2020, ISBN:978-83-8220-112-3), MiszczyÅ ska D., MiszczyÅ ski M. "Wybrane metody badaÅ operacyjnych" (2000, ISBN:83-907712-0-9).

Data recorded as paths or trajectories may be suitably described by curves, which are independent of their parametrization. For the space of such curves, the package provides functionalities for reading curves, sampling points on curves, calculating distance between curves and for computing Tukey curve depth of a curve w.r.t. to a bundle of curves. For details see Lafaye De Micheaux, Mozharovskyi, and Vimond (2021) <doi:10.48550/arXiv.1901.00180>.

Pull raw and pre-cleaned versions of national and state-level COVID-19 time-series data from covid19india.org <https://www.covid19india.org>. Easily obtain and merge case count data, testing data, and vaccine data. Also assists in calculating the time-varying effective reproduction number with sensible parameters for COVID-19.

Wrapper functions to model and extract various quantitative information from absorption spectra of chromophoric dissolved organic matter (CDOM).

In the context of paid research studies and clinical trials, budget considerations and patient sampling from available populations are subject to inherent constraints. We introduce the CDsampling package, which integrates optimal design theories within the framework of constrained sampling. This package offers the possibility to find both D-optimal approximate and exact allocations for samplings with or without constraints. Additionally, it provides functions to find constrained uniform sampling as a robust sampling strategy with limited model information. Our package offers functions for the computation of the Fisher information matrix under generalized linear models (including regular linear regression model) and multinomial logistic models.To demonstrate the applications, we also provide a simulated dataset and a real dataset embedded in the package. Yifei Huang, Liping Tong, and Jie Yang (2025)<doi:10.5705/ss.202022.0414>.

Calculate the likelihood ratio test p-value and likelihood confidence intervals for misspecified Cox models, as described in Shao and Guo (2025) <doi:10.48550/arXiv.2508.11851>.

This package performs simulation-based inference as an alternative to the delta method for obtaining valid confidence intervals and p-values for regression post-estimation quantities, such as average marginal effects and predictions at representative values. This framework for simulation-based inference is especially useful when the resulting quantity is not normally distributed and the delta method approximation fails. The methodology is described in Greifer, et al. (2025) <doi:10.32614/RJ-2024-015>. clarify is meant to replace some of the functionality of the archived package Zelig'; see the vignette "Translating Zelig to clarify" for replicating this functionality.

Record and generate a gif of your R sessions plots. When creating a visualization, there is inevitably iteration and refinement that occurs. Automatically save the plots made to a specified directory, previewing them as they would be saved. Then combine all plots generated into a gif to show the plot refinement over time.

Merging data from multiple sources is a relevant approach for comprehensively evaluating complex systems. However, the inherent problems encountered when analyzing single tables are amplified with the generation of multi-block datasets, and finding the relationships between data layers of increasing complexity constitutes a challenging task. For that purpose, a generic methodology is proposed by combining the strength of established data analysis strategies, i.e. multi-block approaches and the Orthogonal Partial Least Squares (OPLS) framework to provide an efficient tool for the fusion of data obtained from multiple sources. The package enables quick and efficient implementation of the consensus OPLS model for any horizontal multi-block data structures (observation-based matching). Moreover, it offers an interesting range of metrics and graphics to help to determine the optimal number of components and check the validity of the model through permutation tests. Interpretation tools include score and loading plots, Variable Importance in Projection (VIP), functionality predict for SHAP computing, and performance coefficients such as R2, Q2, and DQ2 coefficients. J. Boccard and D.N. Rutledge (2013) <doi:10.1016/j.aca.2013.01.022>.

The data and meta data from Statistics Netherlands (<https://www.cbs.nl>) can be browsed and downloaded. The client uses the open data API of Statistics Netherlands.

An algorithm for identifying candidate driver combinations in cancer. CRSO is based on a theoretical model of cancer in which a cancer rule is defined to be a collection of two or more events (i.e., alterations) that are minimally sufficient to cause cancer. A cancer rule set is a set of cancer rules that collectively are assumed to account for all of ways to cause cancer in the population. In CRSO every event is designated explicitly as a passenger or driver within each patient. Each event is associated with a patient-specific, event-specific passenger penalty, reflecting how unlikely the event would have happened by chance, i.e., as a passenger. CRSO evaluates each rule set by assigning all samples to a rule in the rule set, or to the null rule, and then calculating the total statistical penalty from all unassigned event. CRSO uses a three phase procedure find the best rule set of fixed size K for a range of Ks. A core rule set is then identified from among the best rule sets of size K as the rule set that best balances rule set size and statistical penalty. Users should consult the crso vignette for an example walk through of a full CRSO run. The full description, of the CRSO algorithm is presented in: Klein MI, Cannataro V, Townsend J, Stern DF and Zhao H. "Identifying combinations of cancer driver in individual patients." BioRxiv 674234 [Preprint]. June 19, 2019. <doi:10.1101/674234>. Please cite this article if you use crso'.

Convex Partition is a black-box optimisation algorithm for single objective real-parameters functions. The basic principle is to progressively estimate and exploit a regression tree similar to a CART (Classification and Regression Tree) of the objective function. For more details see de Paz (2024) <doi:10.1007/978-3-031-62836-8_3> and Loh (2011) <doi:10.1002/widm.8> .

This package provides a tidied subset of the US College Scorecard dataset, containing institutional characteristics, enrollment, student aid, costs, and student outcomes at institutions of higher education in the United States.