This package contains functions for testing for significant differences between multiple coefficients of variation. Includes Feltz and Miller's (1996) <DOI:10.1002/(SICI)1097-0258(19960330)15:6%3C647::AID-SIM184%3E3.0.CO;2-P> asymptotic test and Krishnamoorthy and Lee's (2014) <DOI:10.1007/s00180-013-0445-2> modified signed-likelihood ratio test. See the vignette for more, including full details of citations.

This package provides functions to perform comparative causal mediation analysis to compare the mediation effects of different treatments via a common mediator. Results contain the estimates and confidence intervals for the two comparative causal mediation analysis estimands, as well as the ATE and ACME for each treatment. Functions provided in the package will automatically assess the comparative causal mediation analysis scope conditions (i.e. for each comparative causal mediation estimand, a numerator and denominator that are both estimated with the desired statistical significance and of the same sign). Results will be returned for each comparative causal mediation estimand only if scope conditions are met for it. See details in Bansak(2020)<doi:10.1017/pan.2019.31>.

Enables user interactivity with large-language models ('LLM') inside the RStudio integrated development environment (IDE). The user can interact with the model using the shiny app included in this package, or directly in the R console. It comes with back-ends for OpenAI', GitHub Copilot', and LlamaGPT'.

This package provides functions to check whether a vector of p-values respects the assumptions of FDR (false discovery rate) control procedures and to compute adjusted p-values.

This package provides a one-stop shop for intuitive and dependency-free color and palette creation and modification. Includes palettes and functionality from popular packages such as viridis', RColorBrewer', and base R grDevices', as well as ggplot2 plot bindings. Users can generate perceptually uniform and colorblind-friendly palettes, adjust palettes in HSL and RGB color spaces, map color gradients to value ranges, and create color-generating functions.

Toolkit for processing and calling interactions in capture Hi-C data. Converts BAM files into counts of reads linking restriction fragments, and identifies pairs of fragments that interact more than expected by chance. Significant interactions are identified by comparing the observed read count to the expected background rate from a count regression model.

Many modern C/C++ development tools in the clang toolchain, such as clang-tidy or clangd', rely on the presence of a compilation database in JSON format <https://clang.llvm.org/docs/JSONCompilationDatabase.html>. This package temporarily injects additional build flags into the R build process to generate such a compilation database.

This package provides functions for clustering regions that form convergence clubs, according to the definition of Phillips and Sul (2009) <doi:10.1002/jae.1080>. A package description is available in Sichera and Pizzuto (2019).

An algorithm for identifying candidate driver combinations in cancer. CRSO is based on a theoretical model of cancer in which a cancer rule is defined to be a collection of two or more events (i.e., alterations) that are minimally sufficient to cause cancer. A cancer rule set is a set of cancer rules that collectively are assumed to account for all of ways to cause cancer in the population. In CRSO every event is designated explicitly as a passenger or driver within each patient. Each event is associated with a patient-specific, event-specific passenger penalty, reflecting how unlikely the event would have happened by chance, i.e., as a passenger. CRSO evaluates each rule set by assigning all samples to a rule in the rule set, or to the null rule, and then calculating the total statistical penalty from all unassigned event. CRSO uses a three phase procedure find the best rule set of fixed size K for a range of Ks. A core rule set is then identified from among the best rule sets of size K as the rule set that best balances rule set size and statistical penalty. Users should consult the crso vignette for an example walk through of a full CRSO run. The full description, of the CRSO algorithm is presented in: Klein MI, Cannataro V, Townsend J, Stern DF and Zhao H. "Identifying combinations of cancer driver in individual patients." BioRxiv 674234 [Preprint]. June 19, 2019. <doi:10.1101/674234>. Please cite this article if you use crso'.

Interface to easily access Cropland Data Layer (CDL) data for any area of interest via the CropScape <https://nassgeodata.gmu.edu/CropScape/> web service.

Integrates two numerical omics data sets from the same samples using partial correlations. The output can be represented as a network, bipartite graph or a hypergraph structure. The method used in the package refers to Klaus et al (2021) <doi:10.1016/j.molmet.2021.101295>.

Code for a variety of nonlinear conditional independence tests: Kernel conditional independence test (Zhang et al., UAI 2011, <arXiv:1202.3775>), Residual Prediction test (based on Shah and Buehlmann, <arXiv:1511.03334>), Invariant environment prediction, Invariant target prediction, Invariant residual distribution test, Invariant conditional quantile prediction (all from Heinze-Deml et al., <arXiv:1706.08576>).

Utilizes spatial association marginal contributions derived from spatial stratified heterogeneity to capture the degree of correlation between spatial patterns.

This package implements the estimation and inference methods for counterfactual analysis described in Chernozhukov, Fernandez-Val and Melly (2013) <DOI:10.3982/ECTA10582> "Inference on Counterfactual Distributions," Econometrica, 81(6). The counterfactual distributions considered are the result of changing either the marginal distribution of covariates related to the outcome variable of interest, or the conditional distribution of the outcome given the covariates. They can be applied to estimate quantile treatment effects and wage decompositions.

Implementations of canonical associative learning models, with tools to run experiment simulations, estimate model parameters, and compare model representations. Experiments and results are represented using S4 classes and methods.

Download and read data on United States congressional proceedings. Data is read from the Library of Congress's Congress.gov Application Programming Interface (<https://github.com/LibraryOfCongress/api.congress.gov/>). Functions exist for all version 3 endpoints, including for bills, amendments, congresses, summaries, members, reports, communications, nominations, and treaties.

CUR/CX decomposition factorizes a matrix into two factor matrices and Multidimensional CX Decomposition factorizes a tensor into a core tensor and some factor matrices. See the reference section of GitHub README.md <https://github.com/rikenbit/ccTensor>, for details of the methods.

This package provides functions for estimating and reporting multi-year averages and corresponding confidence intervals and distributions. A potential use case is reporting the chemical and ecological status of surface waters according to the European Water Framework Directive.

This package implements a semi-parametric GEE estimator accounting for missing data with Inverse-probability weighting (IPW) and for imbalance in covariates with augmentation (AUG). The estimator IPW-AUG-GEE is Doubly robust (DR).

Perform Nonlinear Mixed-Effects (NLME) Modeling using Certara's NLME-Engine. Access the same Maximum Likelihood engines used in the Phoenix platform, including algorithms for parametric methods, individual, and pooled data analysis. The Quasi-Random Parametric Expectation-Maximization Method (QRPEM) is also supported <https://www.page-meeting.org/default.asp?abstract=2338>. Execution is supported both locally or on remote machines. Remote execution includes support for Linux Sun Grid Engine (SGE), Simple Linux Utility for Resource Management (SLURM) grids, Linux and Windows multicore, and individual runs.

Copula-based imputation methods: parametric and nonparametric algorithms for missing multivariate data through conditional copulas.

Randomization-Based Inference for customized experiments. Computes Fisher-Exact P-Values alongside null randomization distributions. Retrieves counternull sets and generates counternull distributions. Computes Fisher Intervals and Fisher-Adjusted P-Values. Package includes visualization of randomization distributions and Fisher Intervals. Users can input custom test statistics and their own methods for randomization. Rosenthal and Rubin (1994) <doi:10.1111/j.1467-9280.1994.tb00281.x>.

This package provides tools for detecting cellwise outliers and robust methods to analyze data which may contain them. Contains the implementation of the algorithms described in Rousseeuw and Van den Bossche (2018) <doi:10.1080/00401706.2017.1340909> (open access) Hubert et al. (2019) <doi:10.1080/00401706.2018.1562989> (open access), Raymaekers and Rousseeuw (2021) <doi:10.1080/00401706.2019.1677270> (open access), Raymaekers and Rousseeuw (2021) <doi:10.1007/s10994-021-05960-5> (open access), Raymaekers and Rousseeuw (2021) <doi:10.52933/jdssv.v1i3.18> (open access), Raymaekers and Rousseeuw (2022) <doi:10.1080/01621459.2023.2267777> (open access) Rousseeuw (2022) <doi:10.1016/j.ecosta.2023.01.007> (open access). Examples can be found in the vignettes: "DDC_examples", "MacroPCA_examples", "wrap_examples", "transfo_examples", "DI_examples", "cellMCD_examples" , "Correspondence_analysis_examples", and "cellwise_weights_examples".

Predicts 3 to 12 months prognosis in Chronic Obstructive Pulmonary Disease (COPD) patients hospitalized for severe exacerbations, as described in Almagro et al. (2014) <doi:10.1378/chest.13-1328>.