This package provides functions for the evaluation of surrogate endpoints when both the surrogate and the true endpoint are failure time variables. The approaches implemented are: (1) the two-step approach (Burzykowski et al, 2001) <DOI:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at the first step and either a linear regression of log-hazard ratios at the second step (either adjusted or not for measurement error); (2) mixed proportional hazard models estimated via mixed Poisson GLM (Rotolo et al, 2017 <DOI:10.1177/0962280217718582>).

This package provides functions for generating Standardized Climate Indices (SCI). Functions for generating Standardized Climate Indices (SCI). SCI is a transformation of (smoothed) climate (or environmental) time series that removes seasonality and forces the data to take values of the standard normal distribution. SCI was originally developed for precipitation. In this case it is known as the Standardized Precipitation Index (SPI).

This package implements variable selection procedures for low to moderate size generalized linear regressions models. It includes the STOPES functions for linear regression (Capanu M, Giurcanu M, Begg C, Gonen M, Optimized variable selection via repeated data splitting, Statistics in Medicine, 2020, 19(6):2167-2184) as well as subsampling based optimization methods for generalized linear regression models (Marinela Capanu, Mihai Giurcanu, Colin B Begg, Mithat Gonen, Subsampling based variable selection for generalized linear models).

This package performs inference for a class of measures to compare competing risk prediction models with censored survival data. The class includes the integrated discrimination improvement index (IDI) and category-less net reclassification index (NRI).

Fit Cox non-proportional hazards models with time-varying coefficients. Both unpenalized procedures (Newton and proximal Newton) and penalized procedures (P-splines and smoothing splines) are included using B-spline basis functions for estimating time-varying coefficients. For penalized procedures, cross validations, mAIC, TIC or GIC are implemented to select tuning parameters. Utilities for carrying out post-estimation visualization, summarization, point-wise confidence interval and hypothesis testing are also provided. For more information, see Wu et al. (2022) <doi: 10.1007/s10985-021-09544-2> and Luo et al. (2023) <doi:10.1177/09622802231181471>.

Use of Knock Out and Round Robin Techniques in preparing tournament fixtures as discussed in the Book Health and Physical Education by Dr. V K Sharma'(2018,ISBN:978-93-5272-134-4).

We designed this package to provide several functions for area level of small area estimation using hierarchical Bayesian (HB) method. This package provides model using panel data for variable interest.This package also provides a dataset produced by a data generation. The rjags package is employed to obtain parameter estimates. Model-based estimators involves the HB estimators which include the mean and the variation of mean. For the reference, see Rao and Molina (2015).

This package provides utilities for generating SQL queries (particularly CREATE TABLE statements) from R model objects. The most important use case is generating SQL to score a generalized linear model or related model represented as an R object, in which case the package handles parsing formula operators and including the model's response function.

This package performs simulations of binary spatial raster data using the Ising model (Ising (1925) <doi:10.1007/BF02980577>; Onsager (1944) <doi:10.1103/PhysRev.65.117>). It allows to set a few parameters that represent internal and external pressures, and the number of simulations (Stepinski and Nowosad (2023) <doi:10.1098/rsos.231005>).

Recently, regularized variable selection has emerged as a powerful tool to identify and dissect gene-environment interactions. Nevertheless, in longitudinal studies with high dimensional genetic factors, regularization methods for GÃ E interactions have not been systematically developed. In this package, we provide the implementation of sparse group variable selection, based on both the quadratic inference function (QIF) and generalized estimating equation (GEE), to accommodate the bi-level selection for longitudinal GÃ E studies with high dimensional genomic features. Alternative methods conducting only the group or individual level selection have also been included. The core modules of the package have been developed in C++.

Rapidly build accurate genetic prediction models for genome-wide association or whole-genome sequencing study data by smooth-threshold multivariate genetic prediction (STMGP) method. Variable selection is performed using marginal association test p-values with an optimal p-value cutoff selected by Cp-type criterion. Quantitative and binary traits are modeled respectively via linear and logistic regression models. A function that works through PLINK software (Purcell et al. 2007 <DOI:10.1086/519795>, Chang et al. 2015 <DOI:10.1186/s13742-015-0047-8>) <https://www.cog-genomics.org/plink2> is provided. Covariates can be included in regression model.

For biparental, three and four-way crosses Identity by Descent (IBD) probabilities can be calculated using Hidden Markov Models and inheritance vectors following Lander and Green (<https://www.jstor.org/stable/29713>) and Huang (<doi:10.1073/pnas.1100465108>). One of a series of statistical genetic packages for streamlining the analysis of typical plant breeding experiments developed by Biometris.

RegLog system provides a set of shiny modules to handle register procedure for your users, alongside with login, edit credentials and password reset functionality. It provides support for popular SQL databases and optionally googlesheet-based database for easy setup. For email sending it provides support for emayili and gmailr backends. Architecture makes customizing usability pretty straightforward. The authentication system created with shiny.reglog is designed to be optional: user don't need to be logged-in to access your application, but when logged-in the user data can be used to read from and write to relational databases.

This package provides a set of spatial accessibility measures from a set of locations (demand) to another set of locations (supply). It aims, among others, to support research on spatial accessibility to health care facilities. Includes the locations and some characteristics of major public hospitals in Greece.

This package provides data about the Star Wars movie franchise in a set of relational tables or as a complete DuckDB database. All data was collected from the open source Star Wars API.

In stability selection (N Meinshausen, P Bühlmann (2010) <doi:10.1111/j.1467-9868.2010.00740.x>) and consensus clustering (S Monti et al (2003) <doi:10.1023/A:1023949509487>), resampling techniques are used to enhance the reliability of the results. In this package (B Bodinier et al (2025) <doi:10.18637/jss.v112.i05>), hyper-parameters are calibrated by maximising model stability, which is measured under the null hypothesis that all selection (or co-membership) probabilities are identical (B Bodinier et al (2023a) <doi:10.1093/jrsssc/qlad058> and B Bodinier et al (2023b) <doi:10.1093/bioinformatics/btad635>). Functions are readily implemented for the use of LASSO regression, sparse PCA, sparse (group) PLS or graphical LASSO in stability selection, and hierarchical clustering, partitioning around medoids, K means or Gaussian mixture models in consensus clustering.

Sparse Linear Method(SLIM) predicts ratings and top-n recommendations suited for sparse implicit positive feedback systems. SLIM is decomposed into multiple elasticnet optimization problems which are solved in parallel over multiple cores. The package is based on "SLIM: Sparse Linear Methods for Top-N Recommender Systems" by Xia Ning and George Karypis <doi:10.1109/ICDM.2011.134>.

Statistical methods for the modeling and monitoring of time series of counts, proportions and categorical data, as well as for the modeling of continuous-time point processes of epidemic phenomena. The monitoring methods focus on aberration detection in count data time series from public health surveillance of communicable diseases, but applications could just as well originate from environmetrics, reliability engineering, econometrics, or social sciences. The package implements many typical outbreak detection procedures such as the (improved) Farrington algorithm, or the negative binomial GLR-CUSUM method of Hoehle and Paul (2008) <doi:10.1016/j.csda.2008.02.015>. A novel CUSUM approach combining logistic and multinomial logistic modeling is also included. The package contains several real-world data sets, the ability to simulate outbreak data, and to visualize the results of the monitoring in a temporal, spatial or spatio-temporal fashion. A recent overview of the available monitoring procedures is given by Salmon et al. (2016) <doi:10.18637/jss.v070.i10>. For the retrospective analysis of epidemic spread, the package provides three endemic-epidemic modeling frameworks with tools for visualization, likelihood inference, and simulation. hhh4() estimates models for (multivariate) count time series following Paul and Held (2011) <doi:10.1002/sim.4177> and Meyer and Held (2014) <doi:10.1214/14-AOAS743>. twinSIR() models the susceptible-infectious-recovered (SIR) event history of a fixed population, e.g, epidemics across farms or networks, as a multivariate point process as proposed by Hoehle (2009) <doi:10.1002/bimj.200900050>. twinstim() estimates self-exciting point process models for a spatio-temporal point pattern of infective events, e.g., time-stamped geo-referenced surveillance data, as proposed by Meyer et al. (2012) <doi:10.1111/j.1541-0420.2011.01684.x>. A recent overview of the implemented space-time modeling frameworks for epidemic phenomena is given by Meyer et al. (2017) <doi:10.18637/jss.v077.i11>.

This package contains functions and datasets for math taught in school. A main focus is set to prime-calculation.

This package provides basic functions that support an implementation of object case (Case 1) best-worst scaling: a function for converting a two-level orthogonal main-effect design/balanced incomplete block design into questions; two functions for creating a data set suitable for analysis; a function for calculating count-based scores; a function for calculating shares of preference; and a function for generating artificial responses to questions. See Louviere et al. (2015) <doi:10.1017/CBO9781107337855> for details on best-worst scaling, and Aizaki and Fogarty (2023) <doi:10.1016/j.jocm.2022.100394> for the package.

This package implements a suite of sensitivity analysis tools that extends the traditional omitted variable bias framework and makes it easier to understand the impact of omitted variables in regression models, as discussed in Cinelli, C. and Hazlett, C. (2020), "Making Sense of Sensitivity: Extending Omitted Variable Bias." Journal of the Royal Statistical Society, Series B (Statistical Methodology) <doi:10.1111/rssb.12348>.

Species sensitivity distributions are cumulative probability distributions which are fitted to toxicity concentrations for different species as described by Posthuma et al.(2001) <isbn:9781566705783>. The ssdtools package uses Maximum Likelihood to fit distributions such as the gamma, log-logistic, log-normal and log-normal log-normal mixture. Multiple distributions can be averaged using Akaike Information Criteria. Confidence intervals on hazard concentrations and proportions are produced by bootstrapping.

Performance of functional kriging, cokriging, optimal sampling and simulation for spatial prediction of functional data. The framework of spatial prediction, optimal sampling and simulation are extended from scalar to functional data. SpatFD is based on the Karhunen-Loève expansion that allows to represent the observed functions in terms of its empirical functional principal components. Based on this approach, the functional auto-covariances and cross-covariances required for spatial functional predictions and optimal sampling, are completely determined by the sum of the spatial auto-covariances and cross-covariances of the respective score components. The package provides new classes of data and functions for modeling spatial dependence structure among curves. The spatial prediction of curves at unsampled locations can be carried out using two types of predictors, and both of them report, the respective variances of the prediction error. In addition, there is a function for the determination of spatial locations sampling configuration that ensures minimum variance of spatial functional prediction. There are also two functions for plotting predicted curves at each location and mapping the surface at each time point, respectively. References Bohorquez, M., Giraldo, R., and Mateu, J. (2016) <doi:10.1007/s10260-015-0340-9>, Bohorquez, M., Giraldo, R., and Mateu, J. (2016) <doi:10.1007/s00477-016-1266-y>, Bohorquez M., Giraldo R. and Mateu J. (2021) <doi:10.1002/9781119387916>.

This package provides a suite of helper functions to support Bayesian Kernel Machine Regression (BKMR) analyses in environmental health research. It enables the simulation of realistic multivariate exposure data using Multivariate Skewed Gamma distributions, estimation of distributional parameters by subgroup, and application of adaptive, data-driven thresholds for feature selection via Posterior Inclusion Probabilities (PIPs). It is especially suited for handling skewed exposure data and enhancing the interpretability of BKMR results through principled variable selection. The methodology is shown in Hasan et. al. (2025) <doi:10.1101/2025.04.14.25325822>.